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Patent History
- ApplicationUS 12/3437584 2012-04-02
- PublicationUS 2012190029 2012-07-26
Patent Family
- AT 353977 (T) 2007-03-15
- AU 2002324135 (A1) 2003-03-18
- CA 2456140 (A1) 2003-03-13
- CN 1665936 (A) 2005-09-07
- CN 100352939 (C) 2007-12-05
- DE 60218182 (T2) 2008-02-07
- DK 1421211 (T3) 2007-05-29
- EP 1421211 (A2) 2004-05-26
- ES 2280562 (T3) 2007-09-16
- HK 1076840 (A1) 2008-05-23
- JP 2005501566 (A) 2005-01-20
- PT 1421211 (E) 2007-03-30
- US 2003044388 (A1) 2003-03-06
- US 6927028 (B2) 2005-08-09
- US 2009170102 (A1) 2009-07-02
- US 8168382 (B2) 2012-05-01
- US 2005282185 (A1) 2005-12-22
- US 2012190029 (A1) 2012-07-26
- WO 03020974 (A2) 2003-03-13
Supplementary
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published patent: METHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS
Title | METHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS |
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Priority Date | 2012-04-02 US 12/3437584 2008-10-13 US 12/250480 2005-03-07 US 11/075092 2001-08-31 US 09/944951 |
Inventors | |
Issue Date | 30-Nov-2012 |
Citation | US Published patent application US 2012190029. Washington, DC: US Patent and Trademark Office (USPTO), 2012 How to Cite? |
Abstract | In a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA of an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from a mother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample. |
Persistent Identifier | http://hdl.handle.net/10722/177024 |
References |
DC Field | Value | Language |
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dc.date.accessioned | 2012-11-30T08:38:57Z | - |
dc.date.available | 2012-11-30T08:38:57Z | - |
dc.date.issued | 2012-11-30 | - |
dc.identifier.citation | US Published patent application US 2012190029. Washington, DC: US Patent and Trademark Office (USPTO), 2012 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/177024 | - |
dc.description.abstract | In a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA of an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from a mother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample. | en_HK |
dc.title | METHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS | en_HK |
dc.type | Patent | en_US |
dc.description.nature | published_or_final_version | en_US |
dc.contributor.inventor | Lo Dennis Yuk Ming | en_HK |
dc.contributor.inventor | Poon Lit Man | en_HK |
patents.identifier.application | US 12/3437584 | en_HK |
patents.description.assignee | UNIV HONG KONG CHINESE [HK] | en_HK |
patents.description.country | United States of America | en_HK |
patents.date.publication | 2012-07-26 | en_HK |
dc.relation.references | US 2006019278 (A1) 2006-01-26 | en_HK |
dc.relation.references | US 7709194 (B2) 2010-05-04 | en_HK |
dc.relation.references | US 2007275402 (A1) 2007-11-29 | en_HK |
dc.relation.references | US 7901884 (B2) 2011-03-08 | en_HK |
dc.relation.references | US 2010323352 (A1) 2010-12-23 | en_HK |
dc.relation.references | US 8026067 (B2) 2011-09-27 | en_HK |
dc.relation.references | US 6927028 (B2) 2005-08-09 | en_HK |
dc.relation.references | US 2003044388 (A1) 2003-03-06 | en_HK |
patents.date.application | 2012-04-02 | en_HK |
patents.date.priority | 2012-04-02 US 12/3437584 | en_HK |
patents.date.priority | 2008-10-13 US 12/250480 | en_HK |
patents.date.priority | 2005-03-07 US 11/075092 | en_HK |
patents.date.priority | 2001-08-31 US 09/944951 | en_HK |
patents.description.cc | US | en_HK |
patents.identifier.publication | US 2012190029 | en_HK |
patents.relation.family | AT 353977 (T) 2007-03-15 | en_HK |
patents.relation.family | AU 2002324135 (A1) 2003-03-18 | en_HK |
patents.relation.family | CA 2456140 (A1) 2003-03-13 | en_HK |
patents.relation.family | CN 1665936 (A) 2005-09-07 | en_HK |
patents.relation.family | CN 100352939 (C) 2007-12-05 | en_HK |
patents.relation.family | DE 60218182 (T2) 2008-02-07 | en_HK |
patents.relation.family | DK 1421211 (T3) 2007-05-29 | en_HK |
patents.relation.family | EP 1421211 (A2) 2004-05-26 | en_HK |
patents.relation.family | ES 2280562 (T3) 2007-09-16 | en_HK |
patents.relation.family | HK 1076840 (A1) 2008-05-23 | en_HK |
patents.relation.family | JP 2005501566 (A) 2005-01-20 | en_HK |
patents.relation.family | PT 1421211 (E) 2007-03-30 | en_HK |
patents.relation.family | US 2003044388 (A1) 2003-03-06 | en_HK |
patents.relation.family | US 6927028 (B2) 2005-08-09 | en_HK |
patents.relation.family | US 2009170102 (A1) 2009-07-02 | en_HK |
patents.relation.family | US 8168382 (B2) 2012-05-01 | en_HK |
patents.relation.family | US 2005282185 (A1) 2005-12-22 | en_HK |
patents.relation.family | US 2012190029 (A1) 2012-07-26 | en_HK |
patents.relation.family | WO 03020974 (A2) 2003-03-13 | en_HK |
patents.description.kind | A1 | en_HK |
patents.type | Patent_published | en_HK |