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Conference Paper: DTI detection of microstructural changes induced by sleep deprivation
Title | DTI detection of microstructural changes induced by sleep deprivation |
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Authors | |
Issue Date | 2012 |
Publisher | International Society of Magnetic Resonance in Medicine. |
Citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of 20th ISMRM, 2012, no. 0910 How to Cite? |
Abstract | Rapid eye movement (REM) sleep is believed to be critical for memory consolidation. To probe the microstructural changes after sleep deprivation (SD) in vivo, REM-SD and DTI were employed in this study. Significant axial, radial and mean diffusivity decreases were found bilaterally in various locations in hippocampus, suggesting specific layers of hippocampus such as dentate gyrus and CA1 may be more susceptible to SD. Significant FA, axial and mean diffusivity decreases were also detected in cortex. Our results indicated that DTI is sensitive for probing microstructural changes, and can provide insights into the microstructural plasticity associated with sleep and memory. |
Description | Theme: Adapting MR in a Changing World Traditional Poster Session - Neuro A: Animal Models of Brain Disease Other Than Stroke: no. 0910 |
Persistent Identifier | http://hdl.handle.net/10722/165174 |
DC Field | Value | Language |
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dc.contributor.author | Ding, AY | en_US |
dc.contributor.author | Zhou, IY | en_US |
dc.contributor.author | Lee, FYH | en_US |
dc.contributor.author | Wu, EX | en_US |
dc.date.accessioned | 2012-09-20T08:16:02Z | - |
dc.date.available | 2012-09-20T08:16:02Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of 20th ISMRM, 2012, no. 0910 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/165174 | - |
dc.description | Theme: Adapting MR in a Changing World | - |
dc.description | Traditional Poster Session - Neuro A: Animal Models of Brain Disease Other Than Stroke: no. 0910 | - |
dc.description.abstract | Rapid eye movement (REM) sleep is believed to be critical for memory consolidation. To probe the microstructural changes after sleep deprivation (SD) in vivo, REM-SD and DTI were employed in this study. Significant axial, radial and mean diffusivity decreases were found bilaterally in various locations in hippocampus, suggesting specific layers of hippocampus such as dentate gyrus and CA1 may be more susceptible to SD. Significant FA, axial and mean diffusivity decreases were also detected in cortex. Our results indicated that DTI is sensitive for probing microstructural changes, and can provide insights into the microstructural plasticity associated with sleep and memory. | - |
dc.language | eng | en_US |
dc.publisher | International Society of Magnetic Resonance in Medicine. | - |
dc.relation.ispartof | Proceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012 | en_US |
dc.title | DTI detection of microstructural changes induced by sleep deprivation | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Zhou, IY: iriszhou@eee.hku.hk | en_US |
dc.identifier.email | Lee, FYH: frankyhlee@gmail.com | - |
dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
dc.identifier.authority | Wu, EX=rp00193 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.hkuros | 207246 | en_US |
dc.publisher.place | Australia | - |
dc.description.other | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of 20th ISMRM, 2012, no. 0910 | - |