Name Card
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Professor Lung, Maria Li 龍李梅瑞

Title:
Director, Laboratory of Cancer Molecular Genomics
Professor, Chair of Cancer Molecular Genomics, Clinical Oncology
Professor

Contact Information
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Office:

Professor Lung, Maria Li 龍李梅瑞

Title:
Director, Laboratory of Cancer Molecular Genomics
Professor, Chair of Cancer Molecular Genomics, Clinical Oncology
Professor

Curriculum Vitae:

Research Interests:(click to check for cognate researchers)

Also Cited As:
Lung, M

Biography

Maria Lung attended Cornell University in New York for her bachelor’s degree and obtained her PhD from Stanford University in California. After being a postdoctoral fellow at the Massachusetts Institute of Technology in Massachusetts, she joined the Department of Microbiology at the University of Hong Kong. She subsequently moved to the Department of Biology at the Hong Kong University of Science & Technology and became one of its founding members. In 2009, she moved back to the University of Hong Kong and became Chair Professor in the Department of Clinical Oncology.

 
Honours, Awards & Prizes
AwardeesAward DateHonours / Awards / PrizesCategory
2014-06-01Small Project Funding - “Study of alternative splicing of esophageal squamous cell carcinoma through transcriptome analysis in Hong Kong” HK$46,327: University Research Committee
Research Achievement
2014-05-01Advanced Study Institute: Croucher Foundation
Research Achievement
2014-06-01Research Grant 2013-2015 - “Genomic studies of esophageal squamous cell carcinoma familial genetic susceptibility and diagnostic biomarkers” HK$800,000: Asian Cancer Research Fund
Research Achievement
2014-05-01Advances in Nasopharyngeal Carcinoma Studies: Croucher Foundation Advanced Study Institute
Research Achievement
2014-06-01Research Grant 2013-2015 - “The SAA1 polymorphism vs risk factors in ESCC” $785,624 (Co-investigator): Health Medical Research Fund
Research Achievement
2010-06-01Molecular genetics and clinical advances in the study of esophageal and gastric cancers: Advanced Studies Institute: Croucher Foundation
Research Achievement
2014-06-01Research Grant 2014-2015 - “Genomic studies of esophageal squamous cell carcinoma familial genetic susceptibility and diagnostic biomarkers” HK$345,000: Asian Cancer Research Fund
Research Achievement
2014-06-01Research Grant 2013-2015 - “Elucidating the genetic basis for early-age onset NPC in Hong Kong” $1,000,000: Health Medical Research Fund
Research Achievement
2014-06-01GRF Research Grant 2014 - "Secretory NID2, a basement membrane protein facilitating cell adhesion, migration, and metastasis in human cancers" HK$1,122,210: Research Grants Council
Research Achievement
2005-03-01Croucher Senior Research Fellowship: Croucher Foundation
Research Achievement
2014-06-01Research Grant 2013-2015 - “Genetic studies of NPC” $2,155,000: Hong Kong Cancer Fund
Research Achievement
1992-01-01American Academy of Microbiology: American Academy of Microbiology
Research Achievement
2014-02-01Seed Funding Programme for Basic Research - “Establishment of human nasopharyngeal carcinoma in 3D invasion and angiogenesis organotypic culture to study hypoxia-induced tumor invasion and angiogenesis” HK$47,900
Research Achievement
2015-02-01Small Project Funding - “Functional validation of a novel DUB3 somatic mutation in tumors of NPC” HK$80,000: HKU University Research Committee
Research Achievement
2015-05-01Advanced Studies Institute: Croucher Foundation
Research Achievement
2015-02-01(Co-I), Research Grant 2015-2017 - “The effects of IKKbeta-specific inhibitor PS1145 on tumor formation and metastasis in NPC” HK$1,000,000: Health Medical Research Fund
Research Achievement
2014-12-01OncoSeek Dec 2014-Mar 2015, HK$650,000: Technology Start-up Support Scheme for Universities
Research Achievement
2015-06-01Gordon Research Conference, NPC Research Conference, $19,125 USD (2016, alternative years)
Research Achievement
2015-06-01OncoSeek 2015-2017, HK$860,000: Hong Kong Science Park Incubator program
Research Achievement
2015-02-01(Co-I), Research Grant 2015-2017 - “The clinical relevance of telomere attrition and NPC genetic susceptibility” HK$997,845: Health Medical Research Fund
Research Achievement
2015-04-01OncoSeek April 2015-Mar 2016, HK$300,000: Technology Start-up Support Scheme for Universities
Research Achievement
2015-11-01Corporate Sponsor: Lee’s Pharmaceutical (HK) Ltd. 2015-2017 - “Regulation and clinical implication of PD-L1 expression in esophageal tumor cells subjected to chemotherapy” HK$2,598,540: Innovation and Technology Commission
Research Achievement
2015-09-01GRF Research Grant (Competitive Earmarked Research Grant) 2015-2018 - “Functional and mechanistic characterizations of a Candidate Tumor Suppressor Gene, Mirror Image Polydactyly 1, in Nasopharyngeal Carcinoma” HK$971,461 (Transferred from PI to Co-I, due to departure of PI): Research Grants Council
Research Achievement
2016-06-01Research Grant 2016-2019 - “Targeted Genomics and Functional Studies of Novel Cancer Predisposing Genes for Esophageal Squamous Cell Carcinoma” HK$7,570,304: RGC Collaborative Research Fund
Research Achievement
2015-09-01GRF Research Grant 2015-2017 - “Functional and mechanistic investigation of frequent p53 gain-of-function mutations in esophageal squamous cell carcinoma” HK$1,168,311: Research Grants Council
Research Achievement
2014-06-01Small Project Funding - “Pilot Study for Deciphering Methylome of Nasopharyngeal Carcinoma (NPC)” HK$51,732: University Research Committee
Research Achievement
2017-04-01(CO-I), Research grant, "Optimizing the selection of patients with metastatic colorectal cancer for liver resection - An immuno-clinical scoring system incorporating circulating tumor cell enumeration and clinical factors" HK$946,064: Health Medical Research Fund
Research Achievement
2018-06-01Research grant, “Clinical application of enumeration and genomic characterization for non-invasive detection and real-time monitoring of circulating tumor cells for esophageal carcinoma” HK$1,199,732: Health Medical Research Fund
Research Achievement
2018-01-01(Co-I), GRF Research Grant, “Genomic and functional study of rare deleterious germline mutations in candidate genes associated with familial risk for esophageal carcinoma” HK$971,720: Research Grants Council
Research Achievement
2018-03-01“Non-invasive real-time monitoring and next-generation sequencing of circulating tumor cells for improved personalized treatment of metastatic colorectal cancer patients” HK$956,000: SK Yee Medical Foundation
Research Achievement
2017-06-01"Establishing platform technology for use of circulating tumor cells for cancer diagnostics & drug testing" HK$1,000,000: Platform Technology Funding
Research Achievement
2017-02-01"Centre for Nasopharyngeal Carcinoma Research" HK$707,783: FIL Foundation
Research Achievement
2017-07-01“Translational Studies for Elucidation the Tumor Heterogeneity and Molecular Evolution in Metastatic Gastrointestinal Tract Cancers for Personalized Medicine” HK$33,333,000: Theme-based Research Scheme
Research Achievement
2020-07-01(Co-I), Health and Medical Research Fund, "A Computational Framework Using Genomic and Transcriptomic Features for Predicting Resistance to PD-1/PDL-1 Checkpoint Inhibition in Gastrointestinal Tract (GIT) cancer", HK$851,952: Food and Health Bureau (FHB)
Research Achievement
2020-07-01(Co-I), Health and Medical Research Fund, "Molecular classification based on microsatellite instability and RAS pathway status as prognostic biomarkers for risk stratification of metastatic relapse in colon carcinoma patients", HK$$1,499,750: Food and Health Bureau (FHB)
Research Achievement
2015-02-01Small Project Funding - “Functional and mechanistic analysis of PHF11 in ESCC epigenetics” HK$42,256: HKU University Research Committee
Research Achievement
2021-01-01(Co-I), "Clinical significance of real-time longitudinal monitoring of liquid biopsies for advanced colorectal cancer" 2021-2024: Health Medical Research Fund
Research Achievement
2022-02-01(Co-I), “Understanding NPC Molecular Subtypes Associated with Clinical Outcome and Their Impact on Tumor Microenvironment” 2022-2025: Health Medical Research Fund
Research Achievement
2022-01-01(Co-I), “Redefining resectability for colorectal liver metastasis: the role of circulating tumor cells and its molecular characteristics” 2022-2025: Health Medical Research Fund
Research Achievement
2020-01-01(Co-I), GRF research grant, “Redefining resectability for colorectal liver metastasis: the role of circulating tumor cells and its molecular characteristics” HK$820,060: Research Grants Council
Research Achievement
2019-01-01(Co-I), GRF research grant, “Genomic and functional study by targeting MST1R and its related chromosome 3p21.3 regions associated with genetic susceptibility in NPC” HK$956,853: Research Grants Council
Research Achievement
2020-01-01(Co-I), GRF research grant, “An Epigenetic Landscape Study: Unraveling the Role of Loss of CCCTC-binding Factor CTCF in Epigenetic Dysregulation in Epstein-Barr Virus-positive Nasopharyngeal Carcinoma” HK$1,100,023: Research Grants Council
Research Achievement
2019-06-01(Co-I), Research grant, “Establishment of a patient-derived organoid in vivo drug testing model in ESCC and a pilot study for tumor-associated macrophage targeted therapy” HK$1,484,832: Health Medical Research Fund
Research Achievement
Professional Societies
Term PeriodPositionProfessional Societies
07/2009-Expert PanelInnovation and Technology Support Programme for Industry Department
08/2010-07/2013Biomedical Engineering Programme Advisory CommitteeCUHK
07/2006-07/2012Technology Advisory PanelIncu-Tech Program organized by Hong Kong Science and Technology Parks Corporation (HKSTP)
2013-2020ReviewerGrants Review Board for HMRF
1992FellowAcademy of Microbiology
2017-2020Editorial Board memberAnnals of Nasopharynx Cancer
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