Clinical utility of epigenomic profiling for primary liver tumors in Chinese children
Grant Data
Project Title
Clinical utility of epigenomic profiling for primary liver tumors in Chinese children
Principal Investigator
Professor Chiang, Alan Kwok Shing
(Principal Investigator (PI))
Co-Investigator(s)
Professor Yuan Xiaojun
(Co-Investigator)
Dr. Liu Pak Yin Anthony
(Co-Investigator)
Professor Chiang Alan Kwok Shing
(Co-Investigator)
Professor Yang Wanling
(Co-Investigator)
Professor Chung Brian Hon Yin
(Co-Investigator)
Professor Lo Cheuk Lam Regina
(Co-Investigator)
Professor Chung Ho Yu
(Co-Investigator)
Professor To Ka Fai
(Co-Investigator)
Duration
36
Start Date
2022-07-01
Amount
1472344
Conference Title
Clinical utility of epigenomic profiling for primary liver tumors in Chinese children
Keywords
children, epigenomics, hepatoblastoma, hepatocellular carcinoma, prognosis, stratification
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
09201706
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2021
Status
On-going
Objectives
Primary liver tumors in children include hepatoblastoma (HB) and hepatocellular carcinoma (HCC) and are more common in Asians. A robust clinical risk-stratification schema has been developed but biological heterogeneity among these entities and within HB has not been comprehensively evaluated. Our proposed study investigates the clinical utility of epigenomic profiling in the classification and subgrouping of pediatric liver tumors.