Browsing by Author Sofia, MJ

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Showing results 1 to 6 of 6
TitleAuthor(s)Issue DateViews
 
A single dose of the GalNAc-siRNA, AB-729, results in prolonged reductions in HBsAg, HBcrAg, HBV DNA and HBV RNA in the absence of nucleos (t)ide analogue therapy in HBeAg negative subjects with chronic hepatitis B infection
Proceeding/Conference:Journal of Hepatology
Gane, ESevinsky, HYuen, RMFAnderson, MCloherty, GThi, EPWattamwar, TSofia, MJGray, KAntoniello, DEley, TPicchio, GSims, K
2021
9
 
Inhibition of hepatitis B surface antigen by RNA interference therapeutic AB-729 in chronic hepatitis B patients correlates with suppression of all HBsAg isoforms and HBV RNA
Proceeding/Conference:Journal of Hepatology
Thi, EPYuen, RMFGane, ESevinsky, HSims, KAnderson, MLam, AMSofia, MJCloherty, GPicchio, G
2021
10
 
Inhibition of hepatitis B surface antigen in chronic hepatitis B subjects by RNA interference therapeutic AB-729 is accompanied by upregulation of HBV-specific T cell activation markers
Proceeding/Conference:Journal of Hepatology
Paratala, BPark, J-JGanchua, SCGane, EYuen, RMFLee, ACHMoore, CLam, AMSevinsky, HSims, KAntoniello, DSofia, MJPicchio, GThi, EP
2021
8
 
Repeat dosing of the GalNAc-siRNA AB-729 in subjects with chronic hepatitis B results in robust and sustained HBsAg suppression
Proceeding/Conference:Journal of Hepatology
Yuen, RMFBerliba, ESukeepaisarnjaroen, WStrasser, STangkijvanich, PHolmes, JLeerapun, AJucov, AThi, EPWattamwar, TSofia, MJSevinsky, HGray, KAntoniello, DEley, TPicchio, GSims, KGane, E
2021
14
 
Safety and pharmacodynamics of the GALNAC-siRNA AB-729 in subjects with chronic hepatitis B infection
Proceeding/Conference:Hepatology
Yuen, RMFBerliba, EKim, YJHolmes, JALim, YSStrasser, SISchwabe, CJucov, ALee, ACHThi, EPHarasym, TPamulapati, GRWattamwar, PKunta, JSofia, MJSevinsky, HGray, KEley, TPicchio, GRSims, KGane, EJ
2020
17
 
Safety, tolerability, pharmacokinetics (PK), and antiviral activity of the capsid inhibitor (CI) AB-506 in healthy subjects (HS) and chronic hepatitis B (CHB) subjects
Proceeding/Conference:Hepatology
Yuen, RMFBerliba, ESukeepaisarnjaroen, WAhn, SHTanwandee, TLim, Y-SKim, YJPoovorawan, KTangkijvanich, PChan, HLYEley, TBrown, JMoore, CLee, ACHKim, JThi, EPMani, NRijnbrand, RCole, ASofia, MJPicchio, GRSims, KGane, EJ
2019
43
Showing results 1 to 6 of 6