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Showing results 1 to 14 of 14

	Title	Author(s)	Issue Date	Views
	A phase I/II study of ARO-HSD, an RNA interference therapeutic, for the treatment of non-alcoholic steatohepatitis Journal:Journal of Hepatology	Mak, LY Gane, E Schwabe, C Yoon, KT Heo, J Scott, R Lee, JH Lee, JI Kweon, YO Weltman, M Harrison, SA Neuschwander-Tetri, BA Cusi, K Loomba, R Given, BD Christianson, DR Garcia-Medel, E Yi, M Hamilton, J Yuen, RMF	2022
	Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities Journal:Antiviral Research	Gish, RG Given, BD Lai, CL Locarnini, SA Lau, JYN Lewis, DL Schluep, T	2015	100
	Combination treatments including the small-interfering RNA JNJ-3989 induce rapid and sometimes prolonged viral responses in patients with CHB Journal:Journal of Hepatology	Yuen, MF Locarnini S Lim, TH Strasser, SI Sievert W Cheng, W Thompson, AJ Given, BD Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont, M Lenz, O De Ridder, F Cloherty, G Wong, DKH Schwabe, C Jackson, K Lai, CL Gish, RG Gane, E	14-Oct-2022
	Differential reductions in viral antigens expressed from cccDNAVS integrated DNA in treatment naïve HBeAg positive and negative patients with chronic HBV after RNA interference therapy with ARC-520 Proceeding/Conference:Journal of Hepatology	Yuen, RMF Chan, HLY Liu, K Given, BD Schluep, T Hamilton, J Lai, CL Locarnini, SA Lau, JYN Ferrari, C Gish, RG	2016	115
	Dose response with the RNA interference (RNAi) therapy JNJ-3989 combined with nucleos(t)ide analogue (NA) treatment in expanded cohorts of patients (pts) with chronic hepatitis B (CHB) Proceeding/Conference:Hepatology	Gane, EJ Locarnini, S Lim, TH Strasser, SI Sievert, W Cheng, W Thompson, A Given, BD Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont-Mauviel, M Lenz, O Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, RG Yuen, RMF	2019	1
	Effective inhibition of cccDNA derived mRNA/viral antigens and tolerability with ARC-520 Proceeding/Conference:Hepatology International	Yuen, RMF Chan, HLY Liu, SHK Given, BD Schluep, T Hamilton, J Lai, CL Locarnini, SA Lau, JYN Ferrari, C Gish, RG	2016	83
	Long-term serological, virological and histological responses to RNA inhibition by ARC-520 in Chinese chronic hepatitis B patients on entecavir treatment Journal:Gut	Yuen, MF Wong, DKH Schluep, T Lai, CL Ferrari, C Locarnini, S Lo, RCL Gish, R Hamilton, J Wooddell, CI Mak, LY Given, BD	2021	16
	Prolonged RNA interference therapy with ARC-520 Injection in treatment naïve, HBeAg positive and negative patients with chronic HBV results in significant reductions of HBs antigen Proceeding/Conference:Journal of Hepatology	Yuen, RMF Liu, SHK Chan, HLY Given, BD Schluep, T Hamilton, J Lai, CL Locarnini, SA Lau, JY Ferrari, C Gish, RG	2017
	RNA Interference Therapy for Chronic Hepatitis B Predicts the Importance of Addressing Viral Integration When Developing Novel Cure Strategies Journal:Viruses	Wooddell, CI Gehring, AJ Yuen, MF Given, BD	2021	7
	RNA Interference Therapy With ARC‐520 Results in Prolonged Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis B Infection Journal:Hepatology	Yuen, MF Schiefke, I Yoon, JH Ahn, SH Heo, J Kim, JH Chan, HLY Yoon, KT Klinker, H Manns, M Petersen, J Schluep, T Hamilton, J Given, BD Ferrari, C Lai, CL Locarnini, SA Gish, RG	2020	20
	RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg Journal:Science Translational Medicine	Wooddell, CI Yuen, RMF Chan, HLY Gish, RG Locarnini, SA Chavez, D Ferrari, C Given, BD Hamilton, J Kanner, SB Lai, CL Lai, JYN Schluep, T Xu, Z Lanford, RE Lewis, DL	2017	32
	Safety, Tolerability, and Pharmacokinetics of ARC-520 Injection, an RNA Interference-Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers Journal:Clinical Pharmacology in Drug Development	Schluep, T Lickliter, J Hamilton, J Lewis, DL Lai, CL Lau, JYN Locarnini, SA Gish, RG Given, BD	2017	51
	Short interfering RNA JNJ-3989 combination therapy in chronic hepatitis B (CHB) shows potent reduction of all viral markers but no correlate was identified for HBsAg reduction and baseline factors Proceeding/Conference:APASL 2022, Seoul, Korea, 30 Mar - 3 Apr 2022. Hepatology International	Gane, E Locarnini, S Lim, TH Strasser, SI Sievert, W Cheng, W Thompson, AJ Given, BD Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont, M Lenz, O Ridder, FD Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, R Yuen, RMF	2022
	Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent Journal:Antiviral Research	Gish, RG Yuen, RMF Chan, HLY Given, BD Lai, CL Locarnini, SA Lau, JYN Wooddell, CI Schluep, T Lewis, DL	2015

Showing results 1 to 14 of 14