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Article: Effects of age on hormonal and ultrasound markers of ovarian reserve in Chinese women with proven fertility

TitleEffects of age on hormonal and ultrasound markers of ovarian reserve in Chinese women with proven fertility
Authors
KeywordsAFC
Age
Chinese women
Doppler
Ovarian reserve
Issue Date2003
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
Citation
Human Reproduction, 2003, v. 18 n. 10, p. 2169-2174 How to Cite?
AbstractBackground: A woman's fertility is remarkably reduced with increasing age. Reproductive age can be assessed by a number of ovarian reserve tests. There are very few studies addressing the effects of age on these markers in fertile women, especially in Asia. Methods: On the second to fourth day of the menstrual period, fertile Chinese women with regular monthly cycles and no history of ovarian surgery underwent a transvaginal scan with colour Doppler to determine ovarian volume, total antral follicle count (AFC) and mean peak systolic velocity (PSV) of ovarian stromal blood flow, and their serum FSH and inhibin B levels were checked. Results: Out of 145 women scanned, 119 were included in the final analysis. AFC is the only ovarian reserve marker that was significantly different among four age groups (≥20, 21-30, 31-40 and >40 years). AFC had the best correlation with the age of the women, followed by FSH level and ovarian volume. The decline of AFC with age was 3.8% per year (95% confidence interval 2.7-4.9%) in the conventional linear regression model, which was not improved by the biphasic linear regression model. Conclusion: Of the parameters tested, AFC showed the best correlation with women's age and declined linearly at a rate of 3.8% per year.
Persistent Identifierhttp://hdl.handle.net/10722/87624
ISSN
2015 Impact Factor: 4.621
2015 SCImago Journal Rankings: 2.271
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, EHYen_HK
dc.contributor.authorYeung, WSBen_HK
dc.contributor.authorFong, DYTen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:32:14Z-
dc.date.available2010-09-06T09:32:14Z-
dc.date.issued2003en_HK
dc.identifier.citationHuman Reproduction, 2003, v. 18 n. 10, p. 2169-2174en_HK
dc.identifier.issn0268-1161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87624-
dc.description.abstractBackground: A woman's fertility is remarkably reduced with increasing age. Reproductive age can be assessed by a number of ovarian reserve tests. There are very few studies addressing the effects of age on these markers in fertile women, especially in Asia. Methods: On the second to fourth day of the menstrual period, fertile Chinese women with regular monthly cycles and no history of ovarian surgery underwent a transvaginal scan with colour Doppler to determine ovarian volume, total antral follicle count (AFC) and mean peak systolic velocity (PSV) of ovarian stromal blood flow, and their serum FSH and inhibin B levels were checked. Results: Out of 145 women scanned, 119 were included in the final analysis. AFC is the only ovarian reserve marker that was significantly different among four age groups (≥20, 21-30, 31-40 and >40 years). AFC had the best correlation with the age of the women, followed by FSH level and ovarian volume. The decline of AFC with age was 3.8% per year (95% confidence interval 2.7-4.9%) in the conventional linear regression model, which was not improved by the biphasic linear regression model. Conclusion: Of the parameters tested, AFC showed the best correlation with women's age and declined linearly at a rate of 3.8% per year.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/en_HK
dc.relation.ispartofHuman Reproductionen_HK
dc.rightsHuman Reproduction. Copyright © Oxford University Press.en_HK
dc.subjectAFCen_HK
dc.subjectAgeen_HK
dc.subjectChinese womenen_HK
dc.subjectDoppleren_HK
dc.subjectOvarian reserveen_HK
dc.titleEffects of age on hormonal and ultrasound markers of ovarian reserve in Chinese women with proven fertilityen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-1161&volume=18&issue=10&spage=2169&epage=2174&date=2003&atitle=Effects+of+age+on+hormonal+and+ultrasound+markers+of+ovarian+reserve+in+Chinese+women+with+proven+fertilityen_HK
dc.identifier.emailNg, EHY: nghye@hku.hken_HK
dc.identifier.emailYeung, WSB: wsbyeung@hkucc.hku.hken_HK
dc.identifier.emailFong, DYT: dytfong@hku.hken_HK
dc.identifier.emailHo, PC: pcho@hku.hken_HK
dc.identifier.authorityNg, EHY=rp00426en_HK
dc.identifier.authorityYeung, WSB=rp00331en_HK
dc.identifier.authorityFong, DYT=rp00253en_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/humrep/deg404en_HK
dc.identifier.pmid14507840-
dc.identifier.scopuseid_2-s2.0-0142062960en_HK
dc.identifier.hkuros85379en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0142062960&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume18en_HK
dc.identifier.issue10en_HK
dc.identifier.spage2169en_HK
dc.identifier.epage2174en_HK
dc.identifier.isiWOS:000185600300029-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridNg, EHY=35238184300en_HK
dc.identifier.scopusauthoridYeung, WSB=7102370745en_HK
dc.identifier.scopusauthoridFong, DYT=35261710300en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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