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Conference Paper: Validity and psychometrics of the Chinese (Hong Kong) version of the chronic liver disease questionnaire

TitleValidity and psychometrics of the Chinese (Hong Kong) version of the chronic liver disease questionnaire
Authors
Issue Date2007
PublisherSpringer Verlag Dordrecht.
Citation
14th Annual Conference of the International Society for Quality of Life Research - Health Related QOL Research: From Measurement to Understanding, Toronto, Canada, 10-13 October 2007. How to Cite?
AbstractBackground: The Chronic Liver Disease Questionnaire (CLDQ) is the first available and widely used disease-specific health-related quality of life (HRQOL) measure for chronic liver disease. It has been adapted to different countries but it has not been validated in the Cantonese-speaking Chinese population in Hong Kong (HK) where 8% of the population has chronic hepatitis B infection. Aim: The aim of this study is to translate, validate and test the psychometric properties of the CLDQ for the Chinese population in HK so that we can have a disease-specific HRQOL measures to evaluate the impact of chronic hepatitis B (CHB) infections.and the effectiveness of treatment. Methods: The Chinese (HK) CLDQ was tested on 150 patients in HK. Each patient completed a structured questionnaire on morbidity and socio-demographic, the Chinese (HK) CLDQ and Chinese (HK) SF-36 administered by a trained interviewer. Scaling assumptions were tested by item-domain correlations. Internal reliability was measured by the Cronbach's alpha coefficient (CAC). Two-week test-retest reliability was assessed by intra-class correlation (ICC) coefficients in patients with stable condition. Validity was determined by Spearman correlations between corresponding CLDQ and SF-36 domain scores. The mean CLDQ scores between patients with uncomplicated and complicated CHB groups were compared. Results: The sample consisted of 73 uncomplicated CHB (normal liver function) and 77 complicated (cirrhosis or hepatocellular carcinoma) patients, and 71.3% of them were male. Corresponding item-domain correlations within the same domain were similar and ranged from 0.43 to 0.85 for different domains. Internal consistency (CAC>0.70) and test-retest reliability (ICC=0.59-0.89) were acceptable for all domains. Validity was supported by moderate to strong correlations between the CLDQ and SF-36 scores of similar domains. The mean scores of CLDQ were significantly lower in complicated than uncomplicated CHB for all domains except emotional function, supporting sensitivity. Conclusions: The CLDQ has been shown to be valid, reliable and sensitive for evaluating the HRQOL the Chinese CHB patients in HK.
DescriptionProceedings of the 14th Annual Conference of the International Society for Quality of Life Research, 2007, abstract no. 25/1472, p. A-48
a supplemement to Quality of Life Research journal
Persistent Identifierhttp://hdl.handle.net/10722/86614
ISSN
2015 Impact Factor: 2.429
2015 SCImago Journal Rankings: 1.158

 

DC FieldValueLanguage
dc.contributor.authorLam, ETPen_HK
dc.contributor.authorLam, CLKen_HK
dc.contributor.authorLeung, GMen_HK
dc.contributor.authorMcGhee, SMen_HK
dc.contributor.authorLai, CLen_HK
dc.contributor.authorYuen, RMFen_HK
dc.contributor.authorFong, DYTen_HK
dc.date.accessioned2010-09-06T09:19:12Z-
dc.date.available2010-09-06T09:19:12Z-
dc.date.issued2007en_HK
dc.identifier.citation14th Annual Conference of the International Society for Quality of Life Research - Health Related QOL Research: From Measurement to Understanding, Toronto, Canada, 10-13 October 2007.en_HK
dc.identifier.issn0962-9343en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86614-
dc.descriptionProceedings of the 14th Annual Conference of the International Society for Quality of Life Research, 2007, abstract no. 25/1472, p. A-48-
dc.descriptiona supplemement to Quality of Life Research journal-
dc.description.abstractBackground: The Chronic Liver Disease Questionnaire (CLDQ) is the first available and widely used disease-specific health-related quality of life (HRQOL) measure for chronic liver disease. It has been adapted to different countries but it has not been validated in the Cantonese-speaking Chinese population in Hong Kong (HK) where 8% of the population has chronic hepatitis B infection. Aim: The aim of this study is to translate, validate and test the psychometric properties of the CLDQ for the Chinese population in HK so that we can have a disease-specific HRQOL measures to evaluate the impact of chronic hepatitis B (CHB) infections.and the effectiveness of treatment. Methods: The Chinese (HK) CLDQ was tested on 150 patients in HK. Each patient completed a structured questionnaire on morbidity and socio-demographic, the Chinese (HK) CLDQ and Chinese (HK) SF-36 administered by a trained interviewer. Scaling assumptions were tested by item-domain correlations. Internal reliability was measured by the Cronbach's alpha coefficient (CAC). Two-week test-retest reliability was assessed by intra-class correlation (ICC) coefficients in patients with stable condition. Validity was determined by Spearman correlations between corresponding CLDQ and SF-36 domain scores. The mean CLDQ scores between patients with uncomplicated and complicated CHB groups were compared. Results: The sample consisted of 73 uncomplicated CHB (normal liver function) and 77 complicated (cirrhosis or hepatocellular carcinoma) patients, and 71.3% of them were male. Corresponding item-domain correlations within the same domain were similar and ranged from 0.43 to 0.85 for different domains. Internal consistency (CAC>0.70) and test-retest reliability (ICC=0.59-0.89) were acceptable for all domains. Validity was supported by moderate to strong correlations between the CLDQ and SF-36 scores of similar domains. The mean scores of CLDQ were significantly lower in complicated than uncomplicated CHB for all domains except emotional function, supporting sensitivity. Conclusions: The CLDQ has been shown to be valid, reliable and sensitive for evaluating the HRQOL the Chinese CHB patients in HK.-
dc.languageengen_HK
dc.publisherSpringer Verlag Dordrecht.en_HK
dc.relation.ispartofProceedings of the 14th Annual Conference of the International Society for Quality of Life Researchen_HK
dc.rightsThe original publication is available at www.springerlink.com-
dc.titleValidity and psychometrics of the Chinese (Hong Kong) version of the chronic liver disease questionnaireen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0962-9343&volume=abstract no. 25/1472&spage=A&epage=48&date=2007&atitle=Validity+and+psychometrics+of+the+Chinese+(Hong+Kong)+version+of+the+chronic+liver+disease+questionnaireen_HK
dc.identifier.emailLam, CLK: clklam@hku.hken_HK
dc.identifier.emailLeung, GM: gmleung@hku.hken_HK
dc.identifier.emailMcGhee, SM: smmcghee@hkucc.hku.hken_HK
dc.identifier.emailLai, CL: hrmelcl@hku.hken_HK
dc.identifier.emailYuen, RMF: mfyuen@hkucc.hku.hken_HK
dc.identifier.emailFong, DYT: dytfong@hku.hk, dytfong@hkucc.hku.hken_HK
dc.identifier.authorityLam, CLK=rp00350en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.identifier.authorityMcGhee, SM=rp00393en_HK
dc.identifier.authorityLai, CL=rp00314en_HK
dc.identifier.authorityYuen, RMF=rp00479en_HK
dc.identifier.hkuros143220en_HK
dc.identifier.hkuros194588-
dc.identifier.volumeabstract no. 25/1472-
dc.identifier.spageA-48-
dc.identifier.epageA-48-

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