Name Card
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Professor Lai, Ching Lung 黎青龍

Title:
Chief, Division of Gastroenterology & Hepatology, Dept of Medicine
Simon K Y Lee Professorship in Gastroenterology
Clinical Chair Professor
Professor: Chair of Medicine and Hepatology

Contact Information
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Tel:
2255 4252
Office:

Professor Lai, Ching Lung 黎青龍

Title:
Chief, Division of Gastroenterology & Hepatology, Dept of Medicine
Simon K Y Lee Professorship in Gastroenterology
Clinical Chair Professor
Professor: Chair of Medicine and Hepatology

Curriculum Vitae:

Also Cited As:
Lai, C

Biography

Professor Ching-Lung Lai has applied himself to further the understanding and the treatment of chronic hepatitis B and its complications for over three decades. His studies and clinical trials have contributed significantly to advance the development of knowledge concerning the hepatitis B virus. He performed the first trial of interferon alpha in hepatitis B carrier children in 1987. He was one of the pioneering investigators in the use of nucleoside analogues, including phase 2 and 3 studies of lamivudine (1998), telbivudine (2007) and entecavir (2006). The phases III trials of these three antiviral agents were all published in the New England Journal of Medicine. He was amongst the first to appreciate that nucleoside analogues have to be taken on a long-term basis for continuing viral suppression. This is based on the results on studies of the natural history of his research group: that the majority of complications of chronic hepatitis B occur after HBeAg seroconversion because of continued viral replication. He re-defined the treatment endpoints for chronic hepatitis B; these findings were first presented in the State-of-the-Art Lecture in the AASLD in 2005 where he received a prolonged standing ovation. He has been invited to write the editorial for the phase 3 study of tenofovir (2008)

He and his research group have also carried out studies on the natural history of hepatocellular carcinoma and its treatment starting from 1979 onwards, occult hepatitis B and its implications as well as the long-term follow-up of hepatitis B vaccine recipients. He is still continuing with his research on hepatitis B, notably the use of newer treatment agents such as besifovir and the effect of long-term treatment on the levels of cccDNA in the hepatocytes.

 
Honours, Awards & Prizes
AwardeesAward DateHonours / Awards / PrizesCategory
Cheung, CKY
Sharr, WW
Dai, WC
Lam, BKY
2012-07-01Distinguished Research Paper Award for Young Investigators for Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation: Hong Kong College of Physicians
Research Achievement
2006-12-20Outstanding Research Student Supervisor Award 2005-6: The University of Hong Kong
Teaching Accomplishment
Cheung, CKY
Sharr, WW
Dai, WC
2011-05-01The 2011 Joint International Congress of ILTS, ELITA, & LICAGE, San Francisco, USA - Young Investigators Award for Entecavir vs Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B: International Liver Transplant Society
Research Achievement
Cheung, CKY
Sharr, WW
Dai, WC
2011-05-01The 2011 Joint International Congress of ILTS, ELITA, & LICAGE, San Francisco, USA - Young Investigators Award for Entecavir vs Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B: International Liver Transplant Society
Research Achievement
2001-03-28Unrestricted Biomedical Research Grant of US$500,000 for the years 2001-2005 for distinction in Infectious Diseases: Bristol-Myers Squibb
Research Achievement
2002-10-01Faculty Teaching Award: Faculty of Medicine, University of Hong Kong
Teaching Accomplishment
2004-11-01Outstanding Researcher Award: The University of Hong Kong
Research Achievement
2017-09-01Okuda Lectureship on "Chronic Hepatitis B: HBsAg Seroclearance, cccDNA and Treatment Under Trial" at the Asian Pacific Digestive Week 2017, 24 September 2017, Hong Kong: Journal of Gastroenterology and Hepatology Foundation
Research Achievement
1991-05-01Best Teaching Award on the 80th Anniversary of the University of Hong Kong: The University of Hong Kong
Research Achievement
2014-12-01“Home-grown” scientist: Our Hong Kong Foundation (OHKF)
Research Achievement
2014-11-01Fellow of AASLD (FAASLD): American Association for the Study of Liver Diseases (AASLD), USA
Research Achievement
1997-05-01University Teaching Fellowship: The University of Hong Kong
Research Achievement
2017-06-0145-year Long Service Award: The University of Hong Kong
Research Achievement
2005-11-01Leon Schiff State-of-the-Art Lecture: American Association for the Study of Liver Diseases (AASLD), Annual Meeting, November 11-15, 2005, San Francisco, USA
Research Achievement
1996-05-01Best Teachers Award: Medical Society, The University of Hong Kong
Research Achievement
Professional Societies
Term PeriodPositionProfessional Societies
Since 1986MemberAmerican Association for the Study of Liver Diseases
Since 1996MemberAsian-Pacific Hepatitis B Public Health Strategy Board
1989-1995PresidentHong Kong Association for the Study of Liver Diseases
Since 1995Council MemberHong Kong Association for the Study of Liver Diseases
Since 1993Founding MemberHong Kong Institution of Science
04/2000MemberInternational Advisory Board (IBA) for “Davidson Principles and Practice of Medicine” published by Churchill Livingstone, Harcourt Asia Pte. Ltd.
03/2005External Examiner in Internal MedicineDepartment of Health ( DH ) of the Macau Special Administrative Region
09/1999MemberAsian Pacific Consensus for Diagnosis and Treatment of Chronic Hepatitis B and C by Blackwell Science Asia Pty. Ltd. in Kyoto, Japan
2002ConsultantLilly Research Laboratories, a division of Eli Lilly and Company, USA
Since 1984FellowRoyal College of Physicians of Edinburgh
Since 2003Expert ReviewerResearch Grant Applications, National Medical Research Council, Singapore
2014Member of the Review CommitteeAmerican Association for the Study of Liver Diseases (AASLD)
2002Committee MemberScientific Committee of BioPredictive, University and Hopitaux of Paris, France,
Since 1988FellowRoyal College of Physicians of London
Since 1990Member of Scientific Working Group on Viral Hepatitis PreventionDepartment of Health, Hong Kong
03/2003External Examiner in Medicine for the Final Professional MB, BS ExaminationFaculty of Medicine, National University of Singapore
Since 1991Examiner for Membership ExaminationRoyal College of Physicians
Since 1993FellowRoyal Australasian College of Physicians
1999 =MemberNovirio Pharmaceuticals Limited Scientific Advisory Board (SAB) on viral hepatitis
Since 1992Member of Professional & General Affairs Committee, Liaison SubcommitteeHong Kong College of Physicians
Since 1994Member of Subspecialty Advisory CommitteeHong Kong College of Physicians
Since 1997Board Member of the Specialty Board of Gastroenterology & Hepatology of Hong Kong RegionHong Kong College of Physicians
Since 2010Chairman of the Central Committee on Liver Diseases (CCLD)Hospital Authority
1997-2013Programme Director of Specialty Board of Gastroenterology & Hepatology of Hong Kong RegionHong Kong College of Physicians
Since 1971MemberHong Kong College of Physicians
Since 1987FellowHong Kong College of Physicians
Since 1997FellowRoyal College of Physicians and Surgeons of Glasgow
Since 1991Examiner for the Membership ExaminationRoyal College of Physician, United Kingdom
Since 1975MemberRoyal Colleges of Physicians of Lond & Edin and Royal College of Physicians and Surgeons of Glasg
1999 -MemberBristol-Myers Squibb Hepatitis Advisory Board
2004 - 2007Member of Panel AssessorsMedical Council of Hong Kong
07/2002 - 09/2008Member of the Examination Subcommittee, the Licentiate CommitteeMedical Council of Hong Kong
07/2002 - 08/2008Member of the Licentiate CommitteeMedical Council of Hong Kong
Since 1993FellowHong Kong Academy of Medicine
1987-1989Vice PresidentHong Kong Association for the Study of Liver Diseases
1995Examiner for the Preparatory Course for the Fellowship Examination in Emergency MedicineHong Kong Society for Emergency Medicine and Surgery, Hong Kong
Since 1997Board MemberGlaxo Wellcome International Hepatitis Advisory Group
1987Founding MemberHong Kong Association for the Study of Liver Diseases
Since 1978MemberAsian Pacific Association for the Study of the Liver
2011-2013Executive Committee MemberAsian Pacific Association for the Study of the Liver
1982-1986Executive Committee MemberAsian Pacific Association for the Study of the Liver
Since 2013Honorary FellowHong Kong Society of Gastroenterology
1995-1996PresidentHong Kong Society of Gastroenterology
1992-1996Council MemberHong Kong Society of Gastroenterology
1982Founding MemberHong Kong Society of Gastroenterology
Since 2014FellowAmerican Association for the Study of Liver Diseases (AASLD)
Since 1982DiplomateInternational Board of Proctology
Since 1982MemberInternational Association for the Study of the Liver
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