Name Card
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Professor Lai, Ching Lung 黎青龍

Title:
Chief, Division of Gastroenterology & Hepatology, Dept of Medicine
Simon K Y Lee Professorship in Gastroenterology
Professor: Chair of Medicine and Hepatology
Clinical Chair Professor

Contact Information
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Tel:
2255 4252
Office:

Professor Lai, Ching Lung 黎青龍

Title:
Chief, Division of Gastroenterology & Hepatology, Dept of Medicine
Simon K Y Lee Professorship in Gastroenterology
Professor: Chair of Medicine and Hepatology
Clinical Chair Professor

Curriculum Vitae:

Also Cited As:
Lai, C

Biography

Professor Ching-Lung Lai has applied himself to further the understanding and the treatment of chronic hepatitis B and its complications for over three decades. His studies and clinical trials have contributed significantly to advance the development of knowledge concerning the hepatitis B virus. He performed the first trial of interferon alpha in hepatitis B carrier children in 1987. He was one of the pioneering investigators in the use of nucleoside analogues, including phase 2 and 3 studies of lamivudine (1998), telbivudine (2007) and entecavir (2006). The phases III trials of these three antiviral agents were all published in the New England Journal of Medicine. He was amongst the first to appreciate that nucleoside analogues have to be taken on a long-term basis for continuing viral suppression. This is based on the results on studies of the natural history of his research group: that the majority of complications of chronic hepatitis B occur after HBeAg seroconversion because of continued viral replication. He re-defined the treatment endpoints for chronic hepatitis B; these findings were first presented in the State-of-the-Art Lecture in the AASLD in 2005 where he received a prolonged standing ovation. He has been invited to write the editorial for the phase 3 study of tenofovir (2008)

He and his research group have also carried out studies on the natural history of hepatocellular carcinoma and its treatment starting from 1979 onwards, occult hepatitis B and its implications as well as the long-term follow-up of hepatitis B vaccine recipients. He is still continuing with his research on hepatitis B, notably the use of newer treatment agents such as besifovir and the effect of long-term treatment on the levels of cccDNA in the hepatocytes.

 
Honours, Awards & Prizes
AwardeesAward DateHonours / Awards / PrizesCategory
Cheung, CKY
Sharr, WW
Dai, WC
Lam, BKY
2012-07-01Distinguished Research Paper Award for Young Investigators for Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation: Hong Kong College of Physicians
Research Achievement
Cheung, CKY
Sharr, WW
Dai, WC
2011-05-01The 2011 Joint International Congress of ILTS, ELITA, & LICAGE, San Francisco, USA - Young Investigators Award for Entecavir vs Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B: International Liver Transplant Society
Research Achievement
2006-12-20Award Recipient: Outstanding Research Student Supervisor Award
Teaching Accomplishment
2001-03-28Unrestricted Biomedical Research Grant of US$500,000 for the years 2001-2005 for distinction in Infectious Diseases: Bristol-Myers Squibb
Research Achievement
2002-10-01Faculty Teaching Award: Faculty of Medicine, University of Hong Kong
Teaching Accomplishment
Cheung, CKY
Sharr, WW
Dai, WC
2011-05-01The 2011 Joint International Congress of ILTS, ELITA, & LICAGE, San Francisco, USA - Young Investigators Award for Entecavir vs Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B: International Liver Transplant Society
Research Achievement
2004-11-01Outstanding Researcher Award: The University of Hong Kong
Research Achievement
Professional Societies
Term PeriodPositionProfessional Societies
Since 1987Founding Member & Council MemberHong Kong Association for the Study of Liver Diseases
Since 1993Founding MemberHong Kong Institution of Science
Since 1978MemberAsian Pacific Association for the Study of the Liver
Since 1996MemberAsian-Pacific Hepatitis B Public Health Strategy Board
Since 2003Expert ReviewerResearch Grant Applications, National Medical Research Council, Singapore
Since 1982Founding MemberHong Kong Society of Gastroenterology
Since 1992Member of Professional & General Affairs Committee, Liaison SubcommitteeHong Kong College of Physicians
Since 1994Member of Subspecialty Advisory CommitteeHong Kong College of Physicians
Since 1997Programme Director of Specialty Board of Gastroenterology & HepatologyHong Kong College of Physicians
Since 1982DiplomateInternational Board of Proctology
Since 1991Examiner for the Membership ExaminationRoyal College of Physician, United Kingdom
Since 1982MemberInternational Association for the Study of the Liver
Since 1986MemberAmerican Association for the Study of Liver Diseases
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