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Article: Risks and outcomes of peritonitis after flexible colonoscopy in CAPD patients

TitleRisks and outcomes of peritonitis after flexible colonoscopy in CAPD patients
Authors
KeywordsColonoscopy
Peritonitis
Issue Date2007
PublisherMultimed, Inc. The Journal's web site is located at http://pdiconnect.com
Citation
Peritoneal Dialysis International, 2007, v. 27 n. 5, p. 560-564 How to Cite?
Abstract◆Objective: The ISPD 2005 guidelines for peritonitis recommend antibiotic prophylaxis for patients undergoing cotonoscopy with potypectomy while on continuous ambulatory peritoneal dialysis (CAPD) but there is little literature to support this recommendation. This study aimed to took into the risks and outcomes of peritonitis after colonoscopy in CAPD patients. ◆Patients and Methods: All records of flexible colonoscopy performed on our CAPD patients from January 1994 to January 2006 were retrieved. Demographic and clinical data, use of antibiotics before colonoscopy, endoscopic findings, procedure performed, and peritonitis data were analyzed. ◆Results: 77 CAPD patients underwent 97 colonoscopies. No peritonitis developed in the 18 cases where antibiotics were given before colonoscopy. Among those without antibiotic prophylaxis, 4 episodes of peritonitis occurred within 24 hours after the procedure and 1 occurred 5 days later. All responded to intraperitoneal antibiotics. Colonic biopsy and polypectomy were not associated with more peritonitis (2 in 41 with biopsy vs 3 in 38 without biopsy, p - 0.67; 1 in 30 with polypectomy vs 4 in 49 without polypectomy, p=0.64). ◆Conclusion: The risk of peritonitis after cotonoscopy without antibiotic prophylaxis was 6.3%. All peritonitis episodes responded to intraperitoneal antibiotics. Colonic biopsy or polypectomy did not appear to increase the risk of peritonitis. Although statistically not significant when compared with patients without antibiotic prophylaxis, we observed no peritonitis after colonoscopy in patients that were given antibiotics for prophylactic purposes or for other reasons. The efficacy of prophylactic antibiotics would be better defined by large randomized trials. Copyright © 2007 International Society for Peritoneal Dialysis.
Persistent Identifierhttp://hdl.handle.net/10722/78585
ISSN
2015 Impact Factor: 1.298
2015 SCImago Journal Rankings: 0.683
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYip, Ten_HK
dc.contributor.authorTse, KCen_HK
dc.contributor.authorLam, MFen_HK
dc.contributor.authorCheng, SWen_HK
dc.contributor.authorLui, SLen_HK
dc.contributor.authorTang, Sen_HK
dc.contributor.authorNg, Men_HK
dc.contributor.authorChan, TMen_HK
dc.contributor.authorLai, KNen_HK
dc.contributor.authorLo, WKen_HK
dc.date.accessioned2010-09-06T07:44:30Z-
dc.date.available2010-09-06T07:44:30Z-
dc.date.issued2007en_HK
dc.identifier.citationPeritoneal Dialysis International, 2007, v. 27 n. 5, p. 560-564en_HK
dc.identifier.issn0896-8608en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78585-
dc.description.abstract◆Objective: The ISPD 2005 guidelines for peritonitis recommend antibiotic prophylaxis for patients undergoing cotonoscopy with potypectomy while on continuous ambulatory peritoneal dialysis (CAPD) but there is little literature to support this recommendation. This study aimed to took into the risks and outcomes of peritonitis after colonoscopy in CAPD patients. ◆Patients and Methods: All records of flexible colonoscopy performed on our CAPD patients from January 1994 to January 2006 were retrieved. Demographic and clinical data, use of antibiotics before colonoscopy, endoscopic findings, procedure performed, and peritonitis data were analyzed. ◆Results: 77 CAPD patients underwent 97 colonoscopies. No peritonitis developed in the 18 cases where antibiotics were given before colonoscopy. Among those without antibiotic prophylaxis, 4 episodes of peritonitis occurred within 24 hours after the procedure and 1 occurred 5 days later. All responded to intraperitoneal antibiotics. Colonic biopsy and polypectomy were not associated with more peritonitis (2 in 41 with biopsy vs 3 in 38 without biopsy, p - 0.67; 1 in 30 with polypectomy vs 4 in 49 without polypectomy, p=0.64). ◆Conclusion: The risk of peritonitis after cotonoscopy without antibiotic prophylaxis was 6.3%. All peritonitis episodes responded to intraperitoneal antibiotics. Colonic biopsy or polypectomy did not appear to increase the risk of peritonitis. Although statistically not significant when compared with patients without antibiotic prophylaxis, we observed no peritonitis after colonoscopy in patients that were given antibiotics for prophylactic purposes or for other reasons. The efficacy of prophylactic antibiotics would be better defined by large randomized trials. Copyright © 2007 International Society for Peritoneal Dialysis.en_HK
dc.languageengen_HK
dc.publisherMultimed, Inc. The Journal's web site is located at http://pdiconnect.comen_HK
dc.relation.ispartofPeritoneal Dialysis Internationalen_HK
dc.subjectColonoscopyen_HK
dc.subjectPeritonitisen_HK
dc.subject.meshAnti-Bacterial Agents - therapeutic useen_HK
dc.subject.meshColonoscopy - adverse effectsen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInjections, Intraperitonealen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPeritoneal Dialysis, Continuous Ambulatory - adverse effectsen_HK
dc.subject.meshPeritonitis - drug therapy - epidemiology - prevention & controlen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleRisks and outcomes of peritonitis after flexible colonoscopy in CAPD patientsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0896-8608&volume=27&spage=560&epage=564&date=2007&atitle=Risks+and+outcomes+of+peritonitis+after+flexible+colonoscopy+in+CAPD+patientsen_HK
dc.identifier.emailTang, S: scwtang@hku.hken_HK
dc.identifier.emailChan, TM: dtmchan@hku.hken_HK
dc.identifier.emailLai, KN: knlai@hku.hken_HK
dc.identifier.authorityTang, S=rp00480en_HK
dc.identifier.authorityChan, TM=rp00394en_HK
dc.identifier.authorityLai, KN=rp00324en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid17704448-
dc.identifier.scopuseid_2-s2.0-38449121635en_HK
dc.identifier.hkuros134588en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38449121635&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume27en_HK
dc.identifier.issue5en_HK
dc.identifier.spage560en_HK
dc.identifier.epage564en_HK
dc.identifier.isiWOS:000252178000017-
dc.publisher.placeCanadaen_HK
dc.identifier.scopusauthoridYip, T=7004283977en_HK
dc.identifier.scopusauthoridTse, KC=7102609864en_HK
dc.identifier.scopusauthoridLam, MF=7202630163en_HK
dc.identifier.scopusauthoridCheng, SW=36856415600en_HK
dc.identifier.scopusauthoridLui, SL=7102379130en_HK
dc.identifier.scopusauthoridTang, S=7403437082en_HK
dc.identifier.scopusauthoridNg, M=7202076310en_HK
dc.identifier.scopusauthoridChan, TM=7402687700en_HK
dc.identifier.scopusauthoridLai, KN=7402135706en_HK
dc.identifier.scopusauthoridLo, WK=7201502414en_HK

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