Article: Ten-year experience with liver transplantation at Queen Mary Hospital: retrospective study.

File Download Links for fulltext
(May Require Subscription)
Supplementary
  • Basic View
  • Metadata View
  • XML View
TitleTen-year experience with liver transplantation at Queen Mary Hospital: retrospective study.
AuthorsLo, CM1
Fan, ST1
Liu, CL1
Yong, BH1
Lai, CL1
Lau, GK1
Wei, WI1
Tam, PK1
Tsoi, NS1
Ng, IO1
Young, K1
Chan, JK1
Tso, WK1
Yuen, KY1
Wong, J1
Issue Date2002
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
CitationHong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy Of Medicine, 2002, v. 8 n. 4, p. 240-244 [How to Cite?]
AbstractOBJECTIVE: To report the experience with liver transplantation at the Queen Mary Hospital from 1991 to 2000. DESIGN: Retrospective study. SETTING: Liver transplant centre of a University teaching hospital, Hong Kong. PATIENTS: One hundred and forty-eight patients (127 adults and 21 children) who underwent a total of 155 liver transplants using 75 cadaver grafts (full-size, 67; reduced-size, 5; split, 3) and 80 living donor grafts (left lateral segment, 15; left lobe, 6; right lobe, 59) from October 1991 to December 2000 were reviewed. MAIN OUTCOME MEASURES: Graft and patient survival rate. RESULTS: The most common disease indications for liver transplantation were chronic hepatitis B-related liver disease (n=74) in adults and biliary atresia (n=14) in children. Eighteen patients had hepatocellular carcinoma. Forty-eight (31%) liver transplants (three ABO-incompatible) were performed in high-urgency situations for patients requiring intensive care. The proportion of living donor liver transplants was 47.7% in adults and 73.9% in children. The overall 1-year and 5-year patient survival rates were 82% and 77%, respectively. The survival of high-risk recipients, such as those with fulminant hepatic failure (80%), chronic hepatitis B (81%), or hepatocellular carcinoma (94%), was not inferior to that of other patients. CONCLUSION: Over the last decade, the promotion of (cadaver) organ donation through public education coupled with innovative techniques in living donor liver transplantation have enabled a liver transplantation programme to be established in Hong Kong with gratifying results.
ISSN1024-2708
2011 SCImago Journal Rankings: 0.054
DC Field
Value
dc.contributor.authorLo, CM
dc.contributor.authorFan, ST
dc.contributor.authorLiu, CL
dc.contributor.authorYong, BH
dc.contributor.authorLai, CL
dc.contributor.authorLau, GK
dc.contributor.authorWei, WI
dc.contributor.authorTam, PK
dc.contributor.authorTsoi, NS
dc.contributor.authorNg, IO
dc.contributor.authorYoung, K
dc.contributor.authorChan, JK
dc.contributor.authorTso, WK
dc.contributor.authorYuen, KY
dc.contributor.authorWong, J
dc.date.accessioned2007-10-30T06:18:09Z
dc.date.available2007-10-30T06:18:09Z
dc.date.issued2002
dc.description.abstractOBJECTIVE: To report the experience with liver transplantation at the Queen Mary Hospital from 1991 to 2000. DESIGN: Retrospective study. SETTING: Liver transplant centre of a University teaching hospital, Hong Kong. PATIENTS: One hundred and forty-eight patients (127 adults and 21 children) who underwent a total of 155 liver transplants using 75 cadaver grafts (full-size, 67; reduced-size, 5; split, 3) and 80 living donor grafts (left lateral segment, 15; left lobe, 6; right lobe, 59) from October 1991 to December 2000 were reviewed. MAIN OUTCOME MEASURES: Graft and patient survival rate. RESULTS: The most common disease indications for liver transplantation were chronic hepatitis B-related liver disease (n=74) in adults and biliary atresia (n=14) in children. Eighteen patients had hepatocellular carcinoma. Forty-eight (31%) liver transplants (three ABO-incompatible) were performed in high-urgency situations for patients requiring intensive care. The proportion of living donor liver transplants was 47.7% in adults and 73.9% in children. The overall 1-year and 5-year patient survival rates were 82% and 77%, respectively. The survival of high-risk recipients, such as those with fulminant hepatic failure (80%), chronic hepatitis B (81%), or hepatocellular carcinoma (94%), was not inferior to that of other patients. CONCLUSION: Over the last decade, the promotion of (cadaver) organ donation through public education coupled with innovative techniques in living donor liver transplantation have enabled a liver transplantation programme to be established in Hong Kong with gratifying results.
dc.description.naturepublished_or_final_version
dc.format.extent304205 bytes
dc.format.extent3198304 bytes
dc.format.extent3020 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.identifier.citationHong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy Of Medicine, 2002, v. 8 n. 4, p. 240-244 [How to Cite?]
dc.identifier.epage244
dc.identifier.hkuros83500
dc.identifier.issn1024-2708
2011 SCImago Journal Rankings: 0.054
dc.identifier.issue4
dc.identifier.openurl
dc.identifier.pmid12167726
dc.identifier.scopuseid_2-s2.0-0036689582
dc.identifier.spage240
dc.identifier.urihttp://hdl.handle.net/10722/45136
dc.identifier.volume8
dc.languageeng
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
dc.publisher.placeHong Kong
dc.relation.ispartofHong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
dc.subject.meshLiver Transplantation - statistics & numerical data
dc.subject.meshAdolescent
dc.subject.meshHong Kong - epidemiology
dc.subject.meshHospitals, University
dc.subject.meshLiver Diseases - epidemiology
dc.titleTen-year experience with liver transplantation at Queen Mary Hospital: retrospective study.
dc.typeArticle
Author Affiliations
  1. Queen Mary Hospital Hong Kong