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Conference Paper: PACT targeting is a novel viral strategy of innate immune evasion
| Title | PACT targeting is a novel viral strategy of innate immune evasion |
|---|---|
| Authors | |
| Issue Date | 2014 |
| Citation | The 9th Biennial Meeting of the Chinese Society for Immunology (CSI 2014), Jinan, Shandong, China, 18-21 October 2014. How to Cite? |
| Abstract | Innate immunity is the first-line host defense against viral infection.A potent innate interferon response is triggered when viral nucleic acids are sensed by cytoplasmic sensors RIG-I and MDA5.Our recent findings indicate that optimal activation of RIG-I and MDA5 requires double stranded RNA(dsRNA)-binding protein PACT. |
| Persistent Identifier | http://hdl.handle.net/10722/216634 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chan, CP | - |
| dc.contributor.author | Lui, PY | - |
| dc.contributor.author | Fung, KSY | - |
| dc.contributor.author | Kok, KH | - |
| dc.contributor.author | Jin, D | - |
| dc.date.accessioned | 2015-09-18T05:34:02Z | - |
| dc.date.available | 2015-09-18T05:34:02Z | - |
| dc.date.issued | 2014 | - |
| dc.identifier.citation | The 9th Biennial Meeting of the Chinese Society for Immunology (CSI 2014), Jinan, Shandong, China, 18-21 October 2014. | - |
| dc.identifier.uri | http://hdl.handle.net/10722/216634 | - |
| dc.description.abstract | Innate immunity is the first-line host defense against viral infection.A potent innate interferon response is triggered when viral nucleic acids are sensed by cytoplasmic sensors RIG-I and MDA5.Our recent findings indicate that optimal activation of RIG-I and MDA5 requires double stranded RNA(dsRNA)-binding protein PACT. | - |
| dc.language | eng | - |
| dc.relation.ispartof | Proceedings of the 9th Biennial Meeting of the Chinese Society for Immunology, CSI 2014 | - |
| dc.relation.ispartof | 第九届全国免疫学学术大会论文集 | - |
| dc.title | PACT targeting is a novel viral strategy of innate immune evasion | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Chan, CP: chancp10@hku.hk | - |
| dc.identifier.email | Lui, PY: luipy@hku.hk | - |
| dc.identifier.email | Kok, KH: khkok@hku.hk | - |
| dc.identifier.email | Jin, D: dyjin@hku.hk | - |
| dc.identifier.authority | Chan, CP=rp02031 | - |
| dc.identifier.authority | Kok, KH=rp01455 | - |
| dc.identifier.authority | Jin, D=rp00452 | - |
| dc.identifier.hkuros | 253926 | - |