published patent: Novel human virus causing respiratory tract infection and uses thereof

TitleNovel human virus causing respiratory tract infection and uses thereof
Priority Date2005-05-16 US 11/129741
2004-07-21 US 10/895064
Inventors
Issue Date2006
Citation
US Published patent application US 2006034853. Washington, DC: US Patent and Trademark Office (USPTO), 2006 How to Cite?
AbstractThe present invention provides the complete genomic sequence of a novel human coronavirus, coined as human coronavirus-HKU1 ("HCoV-HKU1"), isolated in Hong Kong. The virus belongs to the order Nidovirales of the family Coronaviridae, being a single-stranded RNA virus of positive polarity. Futher study on nasopharyngeal aspirates from patients with community-acquired pnbeumonia has revealed that there are two genotypes, genotype A and genotype B, for this virus. In addition to the genomic sequences of these two genotypes, the invention provides the deduced amino acid sequences of the complete genome of the CoV-HKU1. The nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1 are useful in preventing, diagnosing and/or treating the infection by HCoV-HKU1.; Furthermore, the invention provides immunogenic and vaccine preparations using recombinant and chimeric forms as well as subunits of the HCoV-HKU1 based on the nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1.
Persistent Identifierhttp://hdl.handle.net/10722/176917

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:45Z-
dc.date.available2012-11-30T08:38:45Z-
dc.date.issued2006-
dc.identifier.citationUS Published patent application US 2006034853. Washington, DC: US Patent and Trademark Office (USPTO), 2006en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176917-
dc.description.abstractThe present invention provides the complete genomic sequence of a novel human coronavirus, coined as human coronavirus-HKU1 ("HCoV-HKU1"), isolated in Hong Kong. The virus belongs to the order Nidovirales of the family Coronaviridae, being a single-stranded RNA virus of positive polarity. Futher study on nasopharyngeal aspirates from patients with community-acquired pnbeumonia has revealed that there are two genotypes, genotype A and genotype B, for this virus. In addition to the genomic sequences of these two genotypes, the invention provides the deduced amino acid sequences of the complete genome of the CoV-HKU1. The nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1 are useful in preventing, diagnosing and/or treating the infection by HCoV-HKU1.; Furthermore, the invention provides immunogenic and vaccine preparations using recombinant and chimeric forms as well as subunits of the HCoV-HKU1 based on the nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleNovel human virus causing respiratory tract infection and uses thereofen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorYuen, KYen_HK
dc.contributor.inventorWoo Chiu Yat Pen_HK
dc.contributor.inventorLau Kar Pui Sen_HK
dc.contributor.inventorChan Kwok Hen_HK
dc.contributor.inventorYuen, KYen_HK
dc.contributor.inventorWoo Chiu Yat Patricken_HK
dc.contributor.inventorLau Kar Pui Susannaen_HK
dc.contributor.inventorChan Kwok Hungen_HK
patents.identifier.applicationUS 11/129741en_HK
patents.description.assigneeTHE UNIVERSITY OF HONG KONGen_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2006-02-16en_HK
patents.identifier.hkutechidMicro-2004-00163-2-
patents.date.application2005-05-16en_HK
patents.date.priority2005-05-16 US 11/129741en_HK
patents.date.priority2004-07-21 US 10/895064en_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 2006034853en_HK
patents.identifier.publicationUS 7371837-
patents.relation.familyCN 101076591 (A) 2007-11-21en_HK
patents.relation.familyUS 2006034853 (A1) 2006-02-16en_HK
patents.relation.familyUS 7371837 (B2) 2008-05-13en_HK
patents.relation.familyUS 2006018923 (A1) 2006-01-26en_HK
patents.relation.familyUS 7553944 (B2) 2009-06-30en_HK
patents.relation.familyUS 2009305282 (A1) 2009-12-10en_HK
patents.relation.familyUS 8092994 (B2) 2012-01-10en_HK
patents.relation.familyWO 2006007795 (A1) 2006-01-26en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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