published patent: Novel human virus causing respiratory tract infection and uses thereof

TitleNovel human virus causing respiratory tract infection and uses thereof
Priority Date2004-07-21 US 10/895064
Inventors
Issue Date2007
Citation
China Published Patent Application CN 101076591. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2007 How to Cite?
AbstractThe present invention provides the complete genomic sequence of a novel human coronavirus, coined as human coronavirus- HKU1 (''HCoV-HKU1''), isolated in Hong Kong. The virus belongs to the order Nidovirales of the family Coronaviridae, being a single-stranded RN virus of positive polarity. Futher study on nasopharyngeal aspirates from patients with community-acquired pnbeumonia has revealed that there are two genotypes, genotype A and genotype B, for this virus. In addition to the genomic sequences of these two genotypes, the invention provides the deduced amino acid sequences of the complete genome of the CoV-HKU1. The nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1are useful in preventing, diagnosing and/or treating the infection by HCoV-HKU1. Furthermore, the invention provides immunogenic and vaccine preparations using recombinant and chimeric forms as well as subunits of the HCoV- HKU1 based on the nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1.
Persistent Identifierhttp://hdl.handle.net/10722/176607

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:13Z-
dc.date.available2012-11-30T08:38:13Z-
dc.date.issued2007-
dc.identifier.citationChina Published Patent Application CN 101076591. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2007en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176607-
dc.description.abstractThe present invention provides the complete genomic sequence of a novel human coronavirus, coined as human coronavirus- HKU1 (''HCoV-HKU1''), isolated in Hong Kong. The virus belongs to the order Nidovirales of the family Coronaviridae, being a single-stranded RN virus of positive polarity. Futher study on nasopharyngeal aspirates from patients with community-acquired pnbeumonia has revealed that there are two genotypes, genotype A and genotype B, for this virus. In addition to the genomic sequences of these two genotypes, the invention provides the deduced amino acid sequences of the complete genome of the CoV-HKU1. The nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1are useful in preventing, diagnosing and/or treating the infection by HCoV-HKU1. Furthermore, the invention provides immunogenic and vaccine preparations using recombinant and chimeric forms as well as subunits of the HCoV- HKU1 based on the nucleotide sequences and deduced amino acid sequences of the HCoV-HKU1.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleNovel human virus causing respiratory tract infection and uses thereofen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorYuen, KY-
dc.contributor.inventorWoo, CY-
dc.contributor.inventorLau, KPS-
dc.contributor.inventorChan, KH-
dc.contributor.inventorPoon, LLM-
dc.contributor.inventorPeiris, JSM-
dc.contributor.inventorGuan, Y-
patents.identifier.applicationCN 20058031315en_HK
patents.description.assigneeHONG KONG UNIV [HK]en_HK
patents.description.countryChina, PRCen_HK
patents.date.publication2007-11-21en_HK
patents.date.application2005-07-20en_HK
patents.date.priority2004-07-21 US 10/895064en_HK
patents.description.ccCNen_HK
patents.identifier.publicationCN 101076591en_HK
patents.relation.familyCN 101076591 (A) 2007-11-21en_HK
patents.relation.familyUS 2006034853 (A1) 2006-02-16en_HK
patents.relation.familyUS 7371837 (B2) 2008-05-13en_HK
patents.relation.familyUS 2006018923 (A1) 2006-01-26en_HK
patents.relation.familyUS 7553944 (B2) 2009-06-30en_HK
patents.relation.familyUS 2009305282 (A1) 2009-12-10en_HK
patents.relation.familyUS 8092994 (B2) 2012-01-10en_HK
patents.relation.familyWO 2006007795 (A1) 2006-01-26en_HK
patents.description.kindAen_HK
patents.typePatent_publisheden_HK

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