published patent: CELL-MATRIX MICROSPHERES, METHODS FOR PREPARATION AND APPLICATIONS

TitleCELL-MATRIX MICROSPHERES, METHODS FOR PREPARATION AND APPLICATIONS
Priority Date2007-05-18 PCT/IB2007004413
2006-05-19 US 11/801975P
Inventors
Issue Date2009
Citation
EP Published Patent application EP 2021035. European Patent Office (EPO), Escapenet, 2009 How to Cite?
AbstractA method has been developed to produce stable cell-matrix microspheres with up to 100% encapsulation efficiency and high cell viability, using matrix or biomaterial systems with poor shape and mechanical stability for applications including cell therapeutics via microinjection or surgical implantation, 3D culture for in vitro expansion without repeated cell splitting using enzymatic digestion or mechanical dissociation and for enhanced production of therapeutic biomolecules, and in vitro modeling for morphogenesis studies. The modified droplet generation method is simple and scalable and enables the production of cell-matrix microspheres when the matrix or biomaterial system used has low concentration, with slow phase transition, with poor shape and mechanical stability.
Persistent Identifierhttp://hdl.handle.net/10722/176752
References

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:26Z-
dc.date.available2012-11-30T08:38:26Z-
dc.date.issued2009-
dc.identifier.citationEP Published Patent application EP 2021035. European Patent Office (EPO), Escapenet, 2009en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176752-
dc.description.abstractA method has been developed to produce stable cell-matrix microspheres with up to 100% encapsulation efficiency and high cell viability, using matrix or biomaterial systems with poor shape and mechanical stability for applications including cell therapeutics via microinjection or surgical implantation, 3D culture for in vitro expansion without repeated cell splitting using enzymatic digestion or mechanical dissociation and for enhanced production of therapeutic biomolecules, and in vitro modeling for morphogenesis studies. The modified droplet generation method is simple and scalable and enables the production of cell-matrix microspheres when the matrix or biomaterial system used has low concentration, with slow phase transition, with poor shape and mechanical stability.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleCELL-MATRIX MICROSPHERES, METHODS FOR PREPARATION AND APPLICATIONSen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros167027-
dc.contributor.inventorChan, BPen_HK
dc.contributor.inventorChan, GCFen_HK
dc.contributor.inventorWong, Hoi Lingen_HK
dc.contributor.inventorCheung, PTen_HK
dc.contributor.inventorCheah, KSEen_HK
dc.contributor.inventorChan, Den_HK
patents.identifier.applicationEP 20070872058en_HK
patents.description.assigneeUNIV HONG KONG [CN]en_HK
patents.description.countryEuropean Patent Officeen_HK
patents.date.publication2009-02-11en_HK
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patents.date.application2007-05-18en_HK
patents.date.priority2007-05-18 PCT/IB2007004413en_HK
patents.date.priority2006-05-19 US 11/801975Pen_HK
patents.description.ccEPen_HK
patents.identifier.publicationEP 2021035en_HK
patents.relation.familyCN 101448527 (A) 2009-06-03en_HK
patents.relation.familyEP 2021035 (A2) 2009-02-11en_HK
patents.relation.familyUS 2008031858 (A1) 2008-02-07en_HK
patents.relation.familyUS 2012148537 (A1) 2012-06-14en_HK
patents.relation.familyWO 2008075206 (A2) 2008-06-26en_HK
patents.description.kindA2en_HK
patents.typePatent_publisheden_HK

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