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Article: Malignant melanoma of the female genital tract. A report of nine cases in the Chinese of Hong Kong

TitleMalignant melanoma of the female genital tract. A report of nine cases in the Chinese of Hong Kong
Authors
KeywordsCervix
Malignant melanoma
Vagina
Vulva
Issue Date1991
Citation
Pathology, 1991, v. 23 n. 4, p. 312-317 How to Cite?
AbstractTen cases of malignant melanoma of the female genital tract were diagnosed in Chinese patients in Hong Kong over the 12 yr period from 1978 to 1990. Of the 9 cases considered here, 4 involved the vagina alone, 2 the vagina and cervix, 2 the uterine cervix alone, and 1 occurred on the vulva. Thus, contrary to the usual reported distribution, the vulva was an uncommon site. While the mean age of the patients was 58 yrs, 2 patients were in their thirties and both had a history of a recent pregnancy. Vaginal bleeding or discharge were the presenting symptoms in most cases. The primary origin was confirmed histologically in 6 of the 9 cases and all were of the mucosal lentiginous type. Deep invasion, beyond 3 mm, was present in all cases at the time of diagnosis. Five patients died of the disease 2-22 months after diagnosis. The 4 surviving patients were clinical Stage I and II (FIGO) when diagnosed and have a median survival of 18 months to date. Both the FIGO clinical stage and Breslow's tumor thickness proved to be good prognostic indicators.
Persistent Identifierhttp://hdl.handle.net/10722/147900
ISSN
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKhoo, USen_HK
dc.contributor.authorCollins, RJen_HK
dc.contributor.authorNgan, HYSen_HK
dc.date.accessioned2012-05-29T06:09:49Z-
dc.date.available2012-05-29T06:09:49Z-
dc.date.issued1991en_HK
dc.identifier.citationPathology, 1991, v. 23 n. 4, p. 312-317en_HK
dc.identifier.issn0031-3205en_HK
dc.identifier.urihttp://hdl.handle.net/10722/147900-
dc.description.abstractTen cases of malignant melanoma of the female genital tract were diagnosed in Chinese patients in Hong Kong over the 12 yr period from 1978 to 1990. Of the 9 cases considered here, 4 involved the vagina alone, 2 the vagina and cervix, 2 the uterine cervix alone, and 1 occurred on the vulva. Thus, contrary to the usual reported distribution, the vulva was an uncommon site. While the mean age of the patients was 58 yrs, 2 patients were in their thirties and both had a history of a recent pregnancy. Vaginal bleeding or discharge were the presenting symptoms in most cases. The primary origin was confirmed histologically in 6 of the 9 cases and all were of the mucosal lentiginous type. Deep invasion, beyond 3 mm, was present in all cases at the time of diagnosis. Five patients died of the disease 2-22 months after diagnosis. The 4 surviving patients were clinical Stage I and II (FIGO) when diagnosed and have a median survival of 18 months to date. Both the FIGO clinical stage and Breslow's tumor thickness proved to be good prognostic indicators.en_HK
dc.languageengen_US
dc.relation.ispartofPathologyen_HK
dc.subjectCervixen_HK
dc.subjectMalignant melanomaen_HK
dc.subjectVaginaen_HK
dc.subjectVulvaen_HK
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshChina - Ethnologyen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGenital Neoplasms, Female - Epidemiology - Pathologyen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMelanoma - Epidemiology - Pathologyen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrognosisen_US
dc.subject.meshUterine Cervical Neoplasms - Epidemiology - Pathology - Surgeryen_US
dc.subject.meshVaginal Neoplasms - Epidemiology - Pathology - Radiotherapy - Surgeryen_US
dc.subject.meshVulvar Neoplasms - Epidemiology - Pathology - Radiotherapy - Surgeryen_US
dc.titleMalignant melanoma of the female genital tract. A report of nine cases in the Chinese of Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.emailKhoo, US:uskhoo@hkucc.hku.hken_HK
dc.identifier.emailCollins, RJ:rcollins@hkucc.hku.hken_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityKhoo, US=rp00362en_HK
dc.identifier.authorityCollins, RJ=rp00251en_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1784522en_HK
dc.identifier.scopuseid_2-s2.0-0026336321en_HK
dc.identifier.volume23en_HK
dc.identifier.issue4en_HK
dc.identifier.spage312en_HK
dc.identifier.epage317en_HK
dc.identifier.isiWOS:A1991HJ80000008-
dc.identifier.scopusauthoridKhoo, US=7004195799en_HK
dc.identifier.scopusauthoridCollins, RJ=7403350455en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK

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