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Article: Crescentic IgA glomerulonephritis following interleukin-2 therapy for hepatocellular carcinoma of the liver

TitleCrescentic IgA glomerulonephritis following interleukin-2 therapy for hepatocellular carcinoma of the liver
Authors
Chan, TMCheng, IKPWong, KLChan, KWLai, CL
Issue Date1991
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/AJN
Citation
American Journal Of Nephrology, 1991, v. 11 n. 6, p. 493-496 How to Cite?
DOI: http://dx.doi.org/10.1159/000168366
AbstractA patient who developed crescentic IgA nephropathy following treatment with recombinant interleukin-2 (rIL2) and lymphokine-activated killer (LAK) cell therapy for hepatocellular carcinoma was reported. Cessation of rIL2 and LAK cell treatment plus plasmapheresis and steroid therapy was successful in achieving partial improvement and stabilization of renal function. This is the first case report of biopsy-documented glomerulonephritis developing after IL2 and LAK cell therapy. This provides indirect in vivo evidence for the role of IL2 in mediating glomerular injury in IgA nephropathy.
Persistent Identifierhttp://hdl.handle.net/10722/147898
ISSN
0250-8095
2023 Impact Factor: 4.3
2023 SCImago Journal Rankings: 1.218
ISI Accession Number ID
WOS:A1991HU88600011

 

DC FieldValueLanguage
dc.contributor.authorChan, TMen_HK
dc.contributor.authorCheng, IKPen_HK
dc.contributor.authorWong, KLen_HK
dc.contributor.authorChan, KWen_HK
dc.contributor.authorLai, CLen_HK
dc.date.accessioned2012-05-29T06:09:48Z-
dc.date.available2012-05-29T06:09:48Z-
dc.date.issued1991en_HK
dc.identifier.citationAmerican Journal Of Nephrology, 1991, v. 11 n. 6, p. 493-496en_HK
dc.identifier.issn0250-8095en_HK
dc.identifier.urihttp://hdl.handle.net/10722/147898-
dc.description.abstractA patient who developed crescentic IgA nephropathy following treatment with recombinant interleukin-2 (rIL2) and lymphokine-activated killer (LAK) cell therapy for hepatocellular carcinoma was reported. Cessation of rIL2 and LAK cell treatment plus plasmapheresis and steroid therapy was successful in achieving partial improvement and stabilization of renal function. This is the first case report of biopsy-documented glomerulonephritis developing after IL2 and LAK cell therapy. This provides indirect in vivo evidence for the role of IL2 in mediating glomerular injury in IgA nephropathy.en_HK
dc.languageengen_US
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/AJNen_HK
dc.relation.ispartofAmerican Journal of Nephrologyen_HK
dc.subject.meshBiopsyen_US
dc.subject.meshCarcinoma, Hepatocellular - Therapyen_US
dc.subject.meshFluorescent Antibody Techniqueen_US
dc.subject.meshGlomerulonephritis, Iga - Etiology - Pathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunotherapy, Adoptive - Adverse Effectsen_US
dc.subject.meshInterleukin-2 - Adverse Effectsen_US
dc.subject.meshKidney - Pathologyen_US
dc.subject.meshKiller Cells, Lymphokine-Activated - Transplantationen_US
dc.subject.meshLiver Neoplasms - Therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRecombinant Proteins - Adverse Effectsen_US
dc.titleCrescentic IgA glomerulonephritis following interleukin-2 therapy for hepatocellular carcinoma of the liveren_HK
dc.typeArticleen_HK
dc.identifier.emailChan, TM:dtmchan@hku.hken_HK
dc.identifier.emailChan, KW:hrmtckw@hku.hken_HK
dc.identifier.emailLai, CL:hrmelcl@hku.hken_HK
dc.identifier.authorityChan, TM=rp00394en_HK
dc.identifier.authorityChan, KW=rp00330en_HK
dc.identifier.authorityLai, CL=rp00314en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1159/000168366-
dc.identifier.pmid1668057-
dc.identifier.scopuseid_2-s2.0-0026324672en_HK
dc.identifier.volume11en_HK
dc.identifier.issue6en_HK
dc.identifier.spage493en_HK
dc.identifier.epage496en_HK
dc.identifier.isiWOS:A1991HU88600011-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridChan, TM=7402687700en_HK
dc.identifier.scopusauthoridCheng, IKP=7102537483en_HK
dc.identifier.scopusauthoridWong, KL=7404759833en_HK
dc.identifier.scopusauthoridChan, KW=16444133100en_HK
dc.identifier.scopusauthoridLai, CL=7403086396en_HK
dc.identifier.issnl0250-8095-

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