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Granted Patent: Biofunctional Magnetic Nanoparticles For Pathogen Detection
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TitleBiofunctional Magnetic Nanoparticles For Pathogen Detection
 
Granted PatentUS 7754444
 
Granted Date2010-07-13
 
Priority Date2005-06-23 US 11/159882
2004-06-24 US 11/582700P
 
InventorsXu, Bing
Ho, Pak Leung
Gu, Hongwei
 
Issue Date2010
 
CitationUS Patent 7754444. Washington, DC: US Patent and Trademark Office (USPTO), 2010 [How to Cite?]
 
AbstractThis Invention Provides A Method Of Detecting Pathogens Comprising The Steps Of: (A) Contacting A Sufficient Amount Of Biofunctional Magnetic Nanoparticles With An Appropriate Sample For An Appropriate Period Of Time To Permit The Formation Of Complexes Between The Pathogens In The Sample And The Nanoparticles; (B) Using A Magnetic Field To Aggregate Said Complexes; And (C) Detecting Said Complexes. The Method May Further Comprise The Additional Step Of Removing Said Complexes. The Biofunctional Magnetic Nanoparticles Are Preferably A Conjugate Of Vancomycin And Fept. The Pathogens May Be Bacteria Or Viruses, And The Sample May Be A Solid, Liquid, Or Gas. Detection May Involve Conventional Fluorescence Assay, Enzyme-Linked Immunosorbent Assay (Elisa), Optical Microscope, Electron Microscope, Or A Combination Thereof.; The Sensitivity Of Detection For The Method Is At Least As Low As 10 Colony Forming Units (Cfu) Of The Pathogens In One Milliliter Of Solution Within One Hour.
 
ReferencesUS 4590922 (A) 1986-05-27

US 5279936 (A) 1994-01-18

US 2004247924 (A1) 2004-12-09

US 7186398 (B2) 2007-03-06

US 2004058389 (A1) 2004-03-25

US 7176036 (B2) 2007-02-13

US 2006188876 (A1) 2006-08-24

US 6254662 (B1) 2001-07-03

US 6262129 (B1) 2001-07-17

US 2001009119 (A1) 2001-07-26

US 6302940 (B2) 2001-10-16

US 6620627 (B1) 2003-09-16

DE 10027607 (A1) 2001-12-20

DE 10027607 (C2) 2003-04-03

WO 0110558 (A1) 2001-02-15

WO 0220825 (A1) 2002-03-14

WO 02090565 (A2) 2002-11-14

WO 02090565 (A3) 2004-03-04
 
DC FieldValue
dc.contributor.inventorXu, Bing
 
dc.contributor.inventorHo, Pak Leung
 
dc.contributor.inventorGu, Hongwei
 
dc.date.accessioned2011-10-19T06:32:47Z
 
patents.date.application2005-06-23
 
dc.date.available2011-10-19T06:32:47Z
 
patents.date.granted2010-07-13
 
dc.date.issued2010
 
patents.date.priority2005-06-23 US 11/159882
 
patents.date.priority2004-06-24 US 11/582700P
 
patents.date.publication2006-12-28
 
dc.description.abstractThis Invention Provides A Method Of Detecting Pathogens Comprising The Steps Of: (A) Contacting A Sufficient Amount Of Biofunctional Magnetic Nanoparticles With An Appropriate Sample For An Appropriate Period Of Time To Permit The Formation Of Complexes Between The Pathogens In The Sample And The Nanoparticles; (B) Using A Magnetic Field To Aggregate Said Complexes; And (C) Detecting Said Complexes. The Method May Further Comprise The Additional Step Of Removing Said Complexes. The Biofunctional Magnetic Nanoparticles Are Preferably A Conjugate Of Vancomycin And Fept. The Pathogens May Be Bacteria Or Viruses, And The Sample May Be A Solid, Liquid, Or Gas. Detection May Involve Conventional Fluorescence Assay, Enzyme-Linked Immunosorbent Assay (Elisa), Optical Microscope, Electron Microscope, Or A Combination Thereof.; The Sensitivity Of Detection For The Method Is At Least As Low As 10 Colony Forming Units (Cfu) Of The Pathogens In One Milliliter Of Solution Within One Hour.
 
patents.description.assigneeUniv Hong Kong Science & Techn [Cn]
 
patents.description.ccUS
 
patents.description.countryUnited States of America
 
patents.description.kindB2
 
dc.description.naturepublished_or_final_version
 
patents.identifier.applicationUS 11/159882
 
dc.identifier.citationUS Patent 7754444. Washington, DC: US Patent and Trademark Office (USPTO), 2010 [How to Cite?]
 
patents.identifier.grantedUS 7754444
 
dc.identifier.hkuros106032
 
patents.identifier.hkutechidMicro-2004-00177
 
patents.identifier.publicationUS 20060292555
 
dc.identifier.urihttp://hdl.handle.net/10722/142156
 
patents.relation.familyUS 2006292555 (A1) 2006-12-28
 
patents.relation.familyUS 7754444 (B2) 2010-07-13
 
dc.relation.isreferencedbyWO 2010034846 (A1) 2010-04-01
 
dc.relation.referencesUS 4590922 (A) 1986-05-27
 
dc.relation.referencesUS 5279936 (A) 1994-01-18
 
dc.relation.referencesUS 2004247924 (A1) 2004-12-09
 
dc.relation.referencesUS 7186398 (B2) 2007-03-06
 
dc.relation.referencesUS 2004058389 (A1) 2004-03-25
 
dc.relation.referencesUS 7176036 (B2) 2007-02-13
 
dc.relation.referencesUS 2006188876 (A1) 2006-08-24
 
dc.relation.referencesUS 6254662 (B1) 2001-07-03
 
dc.relation.referencesUS 6262129 (B1) 2001-07-17
 
dc.relation.referencesUS 2001009119 (A1) 2001-07-26
 
dc.relation.referencesUS 6302940 (B2) 2001-10-16
 
dc.relation.referencesUS 6620627 (B1) 2003-09-16
 
dc.relation.referencesDE 10027607 (A1) 2001-12-20
 
dc.relation.referencesDE 10027607 (C2) 2003-04-03
 
dc.relation.referencesWO 0110558 (A1) 2001-02-15
 
dc.relation.referencesWO 0220825 (A1) 2002-03-14
 
dc.relation.referencesWO 02090565 (A2) 2002-11-14
 
dc.relation.referencesWO 02090565 (A3) 2004-03-04
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents
 
dc.titleBiofunctional Magnetic Nanoparticles For Pathogen Detection
 
dc.typePatent
 
patents.typePatent_granted
 
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