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  Patent History
  • Application
    US 11/159882 2005-06-23
  • Publication
    US 2006292555 2006-12-28
Supplementary

published patent: Biofunctional magnetic nanoparticles for pathogen detection

TitleBiofunctional magnetic nanoparticles for pathogen detection
Priority Date2005-06-23 US 11/159882
2004-06-24 US 10/582700P
Inventors
Issue Date2006
Citation
US Published patent application US 2006292555. Washington, DC: US Patent and Trademark Office (USPTO), 2006 How to Cite?
AbstractThis invention provides a method of detecting pathogens comprising the steps of: (a) contacting a sufficient amount of biofunctional magnetic nanoparticles with an appropriate sample for an appropriate period of time to permit the formation of complexes between the pathogens in the sample and the nanoparticles; (b) using a magnetic field to aggregate said complexes; and (c) detecting said complexes. The method may further comprise the additional step of removing said complexes. The biofunctional magnetic nanoparticles are preferably a conjugate of vancomycin and FePt. The pathogens may be bacteria or viruses, and the sample may be a solid, liquid, or gas. Detection may involve conventional fluorescence assay, enzyme-linked immunosorbent assay (ELISA), optical microscope, electron microscope, or a combination thereof.; The sensitivity of detection for the method is at least as low as 10 colony forming units (cfu) of the pathogens in one milliliter of solution within one hour.
Persistent Identifierhttp://hdl.handle.net/10722/176927

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:45Z-
dc.date.available2012-11-30T08:38:45Z-
dc.date.issued2006-
dc.identifier.citationUS Published patent application US 2006292555. Washington, DC: US Patent and Trademark Office (USPTO), 2006en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176927-
dc.description.abstractThis invention provides a method of detecting pathogens comprising the steps of: (a) contacting a sufficient amount of biofunctional magnetic nanoparticles with an appropriate sample for an appropriate period of time to permit the formation of complexes between the pathogens in the sample and the nanoparticles; (b) using a magnetic field to aggregate said complexes; and (c) detecting said complexes. The method may further comprise the additional step of removing said complexes. The biofunctional magnetic nanoparticles are preferably a conjugate of vancomycin and FePt. The pathogens may be bacteria or viruses, and the sample may be a solid, liquid, or gas. Detection may involve conventional fluorescence assay, enzyme-linked immunosorbent assay (ELISA), optical microscope, electron microscope, or a combination thereof.; The sensitivity of detection for the method is at least as low as 10 colony forming units (cfu) of the pathogens in one milliliter of solution within one hour.en_HK
dc.relation.isreferencedbyWO 2010034846 (A1) 2010-04-01en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleBiofunctional magnetic nanoparticles for pathogen detectionen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorXu Bingen_HK
dc.contributor.inventorHo, PLen_HK
dc.contributor.inventorGu Hongweien_HK
patents.identifier.applicationUS 11/159882en_HK
patents.description.assigneeUNIV HONG KONGen_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2006-12-28en_HK
patents.date.application2005-06-23en_HK
patents.date.priority2005-06-23 US 11/159882en_HK
patents.date.priority2004-06-24 US 10/582700Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 2006292555en_HK
patents.relation.familyUS 2006292555 (A1) 2006-12-28en_HK
patents.relation.familyUS 7754444 (B2) 2010-07-13en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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