granted patent: Collagen-Based Microspheres And Methods Of Preparation And Uses Thereof

TitleCollagen-Based Microspheres And Methods Of Preparation And Uses Thereof
Granted PatentUS 7931918
Granted Date2011-04-26
Priority Date2008-07-02 US 12/166670
2005-09-14 US 11/225108
2007-07-06 US /948336P
2004-09-14 US 11/609600P
Inventors
Issue Date2011
Citation
US Patent 7931918. Washington, DC: US Patent and Trademark Office (USPTO), 2011 How to Cite?
AbstractA Method Of Manufacture Of Ecm Microparticles Incorporating Bioactive Molecules For Drug Delivery Has Been Developed, Using A Modified Emulsification Method Or A Water-In-Oil-Phase-Separation Method. The Microspheres Are Photochemically Crosslinked To Control The Release Of The Bioactive Molecules For Better Drug Delivery Usage Without Compromising The Biocompatibility Of The Crosslinked Structures. The Method Uses Mild Fabrication Conditions And Simple Processes, No Toxic Chemical Crosslinking Reagent, Which May Cause Cytotoxicity And Calcification After Implantation, No Organic Solvents, Which May Reduce Drug Availability And Bioactivity, And No Vigorous Stirring Action, Which May Fragmentize Material With Poor Shape And Mechanical Stability And Thus Destabilize The Emulsion.; The Resulting Microparticles Or Microspheres Are Of Controlled Size, Controlled Release, Highly Biocompatible, And Useful For Drug Delivery As Well As Cell Culture.
Persistent Identifierhttp://hdl.handle.net/10722/140415
References

 

DC FieldValueLanguage
dc.date.accessioned2011-09-23T06:11:24Z-
dc.date.available2011-09-23T06:11:24Z-
dc.date.issued2011-
dc.identifier.citationUS Patent 7931918. Washington, DC: US Patent and Trademark Office (USPTO), 2011en_HK
dc.identifier.urihttp://hdl.handle.net/10722/140415-
dc.description.abstractA Method Of Manufacture Of Ecm Microparticles Incorporating Bioactive Molecules For Drug Delivery Has Been Developed, Using A Modified Emulsification Method Or A Water-In-Oil-Phase-Separation Method. The Microspheres Are Photochemically Crosslinked To Control The Release Of The Bioactive Molecules For Better Drug Delivery Usage Without Compromising The Biocompatibility Of The Crosslinked Structures. The Method Uses Mild Fabrication Conditions And Simple Processes, No Toxic Chemical Crosslinking Reagent, Which May Cause Cytotoxicity And Calcification After Implantation, No Organic Solvents, Which May Reduce Drug Availability And Bioactivity, And No Vigorous Stirring Action, Which May Fragmentize Material With Poor Shape And Mechanical Stability And Thus Destabilize The Emulsion.; The Resulting Microparticles Or Microspheres Are Of Controlled Size, Controlled Release, Highly Biocompatible, And Useful For Drug Delivery As Well As Cell Culture.en_HK
dc.languageengen_US
dc.relation.isreferencedbyWO 2012050879 (A2) 2012-04-19en_HK
dc.relation.isreferencedbyWO 2012050879 (A3) 2012-06-07en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleCollagen-Based Microspheres And Methods Of Preparation And Uses Thereofen_HK
dc.typePatenten_US
dc.identifier.emailChan, BP: bpchan@hkucc.hku.hken_US
dc.identifier.emailSo, KF: hrmaskf@hku.hken_US
dc.identifier.authorityChan, BP=rp00087en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros196519en_US
dc.identifier.hkuros197900-
dc.contributor.inventorChan, BPen_US
dc.contributor.inventorChan, CMen_US
dc.contributor.inventorSo, KFen_US
patents.identifier.applicationUS 12/166670en_HK
patents.identifier.grantedUS 7931918en_HK
patents.description.assigneeUniv Hong Kong [Hk]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2008-12-25en_HK
patents.date.granted2011-04-26en_HK
dc.relation.referencesUS 6630156 (B1) 2003-10-07en_HK
dc.relation.referencesUS 2006099268 (A1) 2006-05-11en_HK
dc.relation.referencesUS 7393437 (B2) 2008-07-01en_HK
dc.relation.referencesUS 2006022268 (A1) 2006-02-02en_HK
dc.relation.referencesUS 7271456 (B2) 2007-09-18en_HK
patents.identifier.hkutechidME-2007-00240-1-
patents.date.application2008-07-02en_HK
patents.date.priority2008-07-02 US 12/166670en_HK
patents.date.priority2005-09-14 US 11/225108en_HK
patents.date.priority2007-07-06 US /948336Pen_HK
patents.date.priority2004-09-14 US 11/609600Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20080317866en_HK
patents.relation.familyCN 101868298 (A) 2010-10-20en_HK
patents.relation.familyEP 2175978 (A1) 2010-04-21en_HK
patents.relation.familyUS 2006099268 (A1) 2006-05-11en_HK
patents.relation.familyUS 7393437 (B2) 2008-07-01en_HK
patents.relation.familyUS 2008317866 (A1) 2008-12-25en_HK
patents.relation.familyUS 7931918 (B2) 2011-04-26en_HK
patents.relation.familyWO 2006029571 (A1) 2006-03-23en_HK
patents.relation.familyWO 2009006792 (A1) 2009-01-15en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

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