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Dr Ling, Guang Sheng Heidi 寧珖聖

Title:
Assistant Professor

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Dr Ling, Guang Sheng Heidi 寧珖聖

Title:
Assistant Professor

Research Interests:(click to check for cognate researchers)

Professional Qualifications
YearAwarding InstitutionQualification
The University of Hong KongB.Sc., (Hons)
2005The University of Hong KongMPhil
2009The University of Hong KongPh.D.
Biography

Sustained inflammation causes immune cell dysfunction and forms the common pathological basis for many chronic inflammatory diseases including chronic viral infection, cancer and autoimmunity. A key aspect of immune cell dysfunction that underpins the clinical outcome of these chronic conditions is the development of exhausted CD8+T cells. Nonetheless, reasons for CD8+T cell exhaustion remain incompletely understood. Our laboratory employs the emerging technologies from the field of immunometabolism to assess the effects of sustained inflammation on exhausted T cell differentiation and population diversity. Our long-term goal is to develop metabolism-targeting drugs to regulate T cell immunity in infection, cancer and autoimmunity.

 
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