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Article: Cell technologies for spinal fusion

TitleCell technologies for spinal fusion
Authors
KeywordsBone morphogenetic proteins
Fusion
Mesenchymal stem cell
Osteoprogenitors
Spine
Issue Date2005
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/spinee
Citation
Spine Journal, 2005, v. 5 n. 6 SUPPL., p. 231S-239S How to Cite?
AbstractFor a successful spinal fusion to occur, several vital elements are necessary. They consist of the presence of the bone-forming cell (osteoblast) or its precursor, the appropriate biological signals directing bone synthesis, and a biocompatible scaffold on which the process can occur. The most critical of these components is the osteoblast or its precursor, the mesenchymal stem cell (MSC), both of which possess the ability to form bone. As a result, many current techniques attempt to maximize the benefits derived from harvesting the ready source of MSCs from bone marrow, while minimizing the associated complications. These cellular technologies seek to improve on the harvest and concentration of the MSCs or enhance their delivery and action. This review focuses on the terminology, historical underpinnings, and current research rationale and techniques and discusses the possible future of these technologies. © 2005 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/92937
ISSN
2023 Impact Factor: 4.9
2023 SCImago Journal Rankings: 1.804
References

 

DC FieldValueLanguage
dc.contributor.authorShen, FHen_HK
dc.contributor.authorSamartzis, Den_HK
dc.contributor.authorAn, HSen_HK
dc.date.accessioned2010-09-22T05:04:19Z-
dc.date.available2010-09-22T05:04:19Z-
dc.date.issued2005en_HK
dc.identifier.citationSpine Journal, 2005, v. 5 n. 6 SUPPL., p. 231S-239Sen_HK
dc.identifier.issn1529-9430en_HK
dc.identifier.urihttp://hdl.handle.net/10722/92937-
dc.description.abstractFor a successful spinal fusion to occur, several vital elements are necessary. They consist of the presence of the bone-forming cell (osteoblast) or its precursor, the appropriate biological signals directing bone synthesis, and a biocompatible scaffold on which the process can occur. The most critical of these components is the osteoblast or its precursor, the mesenchymal stem cell (MSC), both of which possess the ability to form bone. As a result, many current techniques attempt to maximize the benefits derived from harvesting the ready source of MSCs from bone marrow, while minimizing the associated complications. These cellular technologies seek to improve on the harvest and concentration of the MSCs or enhance their delivery and action. This review focuses on the terminology, historical underpinnings, and current research rationale and techniques and discusses the possible future of these technologies. © 2005 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/spineeen_HK
dc.relation.ispartofSpine Journalen_HK
dc.subjectBone morphogenetic proteinsen_HK
dc.subjectFusionen_HK
dc.subjectMesenchymal stem cellen_HK
dc.subjectOsteoprogenitorsen_HK
dc.subjectSpineen_HK
dc.titleCell technologies for spinal fusionen_HK
dc.typeArticleen_HK
dc.identifier.emailSamartzis, D:dspine@hku.hken_HK
dc.identifier.authoritySamartzis, D=rp01430en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.spinee.2005.02.008en_HK
dc.identifier.pmid16291118-
dc.identifier.scopuseid_2-s2.0-28244436501en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-28244436501&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue6 SUPPL.en_HK
dc.identifier.spage231Sen_HK
dc.identifier.epage239Sen_HK
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridShen, FH=7201583245en_HK
dc.identifier.scopusauthoridSamartzis, D=34572771100en_HK
dc.identifier.scopusauthoridAn, HS=7202277351en_HK
dc.identifier.issnl1529-9430-

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