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Article: A prospective study on the efficacy of mometasone furoate monohydrate aqueous nasal spray on Chinese patients with allergic rhinitis

TitleA prospective study on the efficacy of mometasone furoate monohydrate aqueous nasal spray on Chinese patients with allergic rhinitis
Authors
KeywordsChemicals And Cas Registry Numbers
Issue Date2003
PublisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/ohns
Citation
Otolaryngology - Head And Neck Surgery, 2003, v. 128 n. 4, p. 497-502 How to Cite?
AbstractOBJECTIVE: We undertook a prospective study of the efficacy of a new intranasal steroid, mometasone furoate nasal spray (Nasonex; Schering-Plough Corp, Kenilworth, NJ). STUDY DESIGN: Chinese patients with allergic rhinitis were recruited. The patients were assessed by a questionnaire that included demographic data and a Rhinitis Symptoms Score. Objective assessments of the nasal passages were performed with a 2.7-mm 30-degree rigid nasoendoscope and scored according to the modified Lund and Kennedy sinusitis staging and scoring for endoscopic appearances of the nasal cavity in rhinosinusitis. Patients were assessed before treatment, and then 200 μg/d MFNS was prescribed. Patients were reevaluated after 8 and 16 weeks of commencement of MFNS. A total of 51 patients completed the 16-week study. RESULTS: There were significant reductions in mean Rhinitis Symptoms Score from 6.19 to 3.8 (P < 0.001) and mean Endoscopic Appearance Score from 4.6 to 3.58 (P = 0.046). Analysis showed that there were reductions in the severity of all 3 aspects of rhinitis symptoms: rhinorrhea, sneezing, and nasal obstruction. CONCLUSION: Mometasone furoate nasal spray was effective in controlling allergic rhinitis and was well tolerated by patients.
Persistent Identifierhttp://hdl.handle.net/10722/92058
ISSN
2023 Impact Factor: 2.6
2023 SCImago Journal Rankings: 1.078
ISI Accession Number ID
References
Errata

 

DC FieldValueLanguage
dc.contributor.authorTsang, RKYen_HK
dc.contributor.authorTong, MCFen_HK
dc.contributor.authorWoo, JKSen_HK
dc.contributor.authorVan Hasselt, CAen_HK
dc.date.accessioned2010-09-17T10:34:51Z-
dc.date.available2010-09-17T10:34:51Z-
dc.date.issued2003en_HK
dc.identifier.citationOtolaryngology - Head And Neck Surgery, 2003, v. 128 n. 4, p. 497-502en_HK
dc.identifier.issn0194-5998en_HK
dc.identifier.urihttp://hdl.handle.net/10722/92058-
dc.description.abstractOBJECTIVE: We undertook a prospective study of the efficacy of a new intranasal steroid, mometasone furoate nasal spray (Nasonex; Schering-Plough Corp, Kenilworth, NJ). STUDY DESIGN: Chinese patients with allergic rhinitis were recruited. The patients were assessed by a questionnaire that included demographic data and a Rhinitis Symptoms Score. Objective assessments of the nasal passages were performed with a 2.7-mm 30-degree rigid nasoendoscope and scored according to the modified Lund and Kennedy sinusitis staging and scoring for endoscopic appearances of the nasal cavity in rhinosinusitis. Patients were assessed before treatment, and then 200 μg/d MFNS was prescribed. Patients were reevaluated after 8 and 16 weeks of commencement of MFNS. A total of 51 patients completed the 16-week study. RESULTS: There were significant reductions in mean Rhinitis Symptoms Score from 6.19 to 3.8 (P < 0.001) and mean Endoscopic Appearance Score from 4.6 to 3.58 (P = 0.046). Analysis showed that there were reductions in the severity of all 3 aspects of rhinitis symptoms: rhinorrhea, sneezing, and nasal obstruction. CONCLUSION: Mometasone furoate nasal spray was effective in controlling allergic rhinitis and was well tolerated by patients.en_HK
dc.languageengen_HK
dc.publisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/ohnsen_HK
dc.relation.ispartofOtolaryngology - Head and Neck Surgeryen_HK
dc.subjectChemicals And Cas Registry Numbersen_HK
dc.titleA prospective study on the efficacy of mometasone furoate monohydrate aqueous nasal spray on Chinese patients with allergic rhinitisen_HK
dc.typeArticleen_HK
dc.identifier.emailTsang, RKY: rkytsang@hku.hken_HK
dc.identifier.authorityTsang, RKY=rp01386en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0194-5998(02)23242-8en_HK
dc.identifier.pmid12707651-
dc.identifier.scopuseid_2-s2.0-0347298739en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0347298739&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume128en_HK
dc.identifier.issue4en_HK
dc.identifier.spage497en_HK
dc.identifier.epage502en_HK
dc.identifier.isiWOS:000182346200008-
dc.publisher.placeUnited Statesen_HK
dc.relation.erratumeid:eid_2-s2.0-23744465348-
dc.identifier.scopusauthoridTsang, RKY=7102940058en_HK
dc.identifier.scopusauthoridTong, MCF=13310275400en_HK
dc.identifier.scopusauthoridWoo, JKS=27268094700en_HK
dc.identifier.scopusauthoridVan Hasselt, CA=7103394173en_HK
dc.identifier.issnl0194-5998-

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