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Article: Heavy tamponade 2 Densiron 68® in routine clinical practice: Anatomical and functional outcomes of a consecutive case series

TitleHeavy tamponade 2 Densiron 68® in routine clinical practice: Anatomical and functional outcomes of a consecutive case series
Authors
Issue Date2008
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/eye
Citation
Eye, 2008, v. 22 n. 10, p. 1360-1365 How to Cite?
AbstractPurpose: To evaluate the safety and efficacy of Densiron 68® in the clinical management of complex vitreoretinal cases with inferior retinal pathology. Methods: We present a prospective interventional non-comparative case series of 122 eyes of 121 consecutive patients. The primary end point was anatomical re-attachment of the retina, defined as retinal re-attachment in the absence of any tamponade agent. The secondary end point was to record the visual function and surgical complications. Inclusion criteria were proliferative vitreoretinopathy, posterior or inferior retinal breaks, and the patient's inability to posture. Results: Patients were 59.9 years (±19.6), (m/f=72:49), (R/L=65:57). Seventy-seven (63.1%) had previous unsuccessful retinal surgery and 45 had Densiron 68 at first procedure. The extent of the detachments was 2.21 quadrants (±1.07) with macular involvement in 66 cases (54%). Eighty-seven (71.3%) patients achieved retinal re-attachment with one retinal operation and ultimately no tamponade, 102 (83.6%) achieved retinal re-attachment with more than one operation and ultimately no tamponade, and 112 (91.3%) patients achieved flat retina with tamponade in situ. Visual acuity rose from 1.38 LogMar (±0.87) to 1.06 (±0.83) (P=0.007). Densiron was removed after 135 days (±73.2; range 35-405). Conclusion: No tamponade agent can provide simultaneous support for the superior as well as the inferior retina; therefore, a tamponade agent that 'sinks' is a welcome new tool at the surgeon's disposal. The sequential use of heavy silicone oil followed by conventional silicone oil may be an acceptable management strategy in recurrent detachment.
Persistent Identifierhttp://hdl.handle.net/10722/90388
ISSN
2023 Impact Factor: 2.8
2023 SCImago Journal Rankings: 1.373
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorStappler, Ten_HK
dc.contributor.authorHeimann, Hen_HK
dc.contributor.authorWong, Den_HK
dc.contributor.authorGibran, SKen_HK
dc.contributor.authorGroenewald, Cen_HK
dc.contributor.authorPearce, IAen_HK
dc.date.accessioned2010-09-06T10:09:40Z-
dc.date.available2010-09-06T10:09:40Z-
dc.date.issued2008en_HK
dc.identifier.citationEye, 2008, v. 22 n. 10, p. 1360-1365en_HK
dc.identifier.issn0950-222Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/90388-
dc.description.abstractPurpose: To evaluate the safety and efficacy of Densiron 68® in the clinical management of complex vitreoretinal cases with inferior retinal pathology. Methods: We present a prospective interventional non-comparative case series of 122 eyes of 121 consecutive patients. The primary end point was anatomical re-attachment of the retina, defined as retinal re-attachment in the absence of any tamponade agent. The secondary end point was to record the visual function and surgical complications. Inclusion criteria were proliferative vitreoretinopathy, posterior or inferior retinal breaks, and the patient's inability to posture. Results: Patients were 59.9 years (±19.6), (m/f=72:49), (R/L=65:57). Seventy-seven (63.1%) had previous unsuccessful retinal surgery and 45 had Densiron 68 at first procedure. The extent of the detachments was 2.21 quadrants (±1.07) with macular involvement in 66 cases (54%). Eighty-seven (71.3%) patients achieved retinal re-attachment with one retinal operation and ultimately no tamponade, 102 (83.6%) achieved retinal re-attachment with more than one operation and ultimately no tamponade, and 112 (91.3%) patients achieved flat retina with tamponade in situ. Visual acuity rose from 1.38 LogMar (±0.87) to 1.06 (±0.83) (P=0.007). Densiron was removed after 135 days (±73.2; range 35-405). Conclusion: No tamponade agent can provide simultaneous support for the superior as well as the inferior retina; therefore, a tamponade agent that 'sinks' is a welcome new tool at the surgeon's disposal. The sequential use of heavy silicone oil followed by conventional silicone oil may be an acceptable management strategy in recurrent detachment.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/eyeen_HK
dc.relation.ispartofEyeen_HK
dc.subject.meshRetinal Detachment - etiology - therapy-
dc.subject.meshRetinal Perforations - complications - surgery - therapy-
dc.subject.meshSilicone Oils - adverse effects-
dc.subject.meshVitrectomy-
dc.subject.meshVitreoretinopathy, Proliferative - complications - therapy-
dc.titleHeavy tamponade 2 Densiron 68® in routine clinical practice: Anatomical and functional outcomes of a consecutive case seriesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0950-222X&volume=22&issue=10&spage=1360&epage=1365&date=2008&atitle=Heavy+tamponade+2+Densiron+68+in+routine+clinical+practice:+anatomical+and+functional+outcomes+of+a+consecutive+case+seriesen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/eye.2008.62en_HK
dc.identifier.pmid18309331-
dc.identifier.scopuseid_2-s2.0-54249139578en_HK
dc.identifier.hkuros152803en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-54249139578&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue10en_HK
dc.identifier.spage1360en_HK
dc.identifier.epage1365en_HK
dc.identifier.isiWOS:000260118200020-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridStappler, T=8563727800en_HK
dc.identifier.scopusauthoridHeimann, H=7006780277en_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK
dc.identifier.scopusauthoridGibran, SK=13205333800en_HK
dc.identifier.scopusauthoridGroenewald, C=6601917086en_HK
dc.identifier.scopusauthoridPearce, IA=35345778700en_HK
dc.identifier.citeulike2451037-
dc.identifier.issnl0950-222X-

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