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Article: Pseudomyxoma peritonei - A heterogenous disease

TitlePseudomyxoma peritonei - A heterogenous disease
Authors
KeywordsPseudomyxoma peritonei
Issue Date1998
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijgo
Citation
International Journal Of Gynecology And Obstetrics, 1998, v. 62 n. 2, p. 173-182 How to Cite?
AbstractObjective: To evaluate the origin of pseudomyxoma peritonei (PMP) in Chinese women. Methods: The clinicopathologic features of 15 cases of PMP were reviewed. Immunostaining using antibodies for CK7 and CK20 was performed in the ovarian, appendiceal and peritoneal lesions of these cases. Results: Appendiceal pathology was documented in five cases, including four mucinous cystadenoma and one simple mucocele. Eight ovarian tumors were found, including seven mucinous cystadenocarcinomas of low malignant potential and one mucinous cystadenoma. Synchronous ovarian and appendiceal lesions were discovered in three cases. One patient had adenocarcinoma of the pancreas. The origin of mucin production was not known in four cases with metastatic adenocarcinoma found in two of them. Immunoreactivity for CK20 was demonstrated in the tissues derived from the peritoneum, ovary, appendix and pancreas while only 23% (3 out of 13 women) of the peritoneal lesions and 33% (2 out of 6 women) of the ovarian tumors were immunoreactive for CK7. Conclusions: PMP is a heterogeneous lesion, which may develop from mucinous metaplasia of the peritoneum or from appendiceal, or ovarian lesions. Careful examination of the ovary and appendix with performance of appendectomy is advised in every case of PMP. Immunohistochemical examination of the peritoneal, ovarian or appendiceal lesions using antibodies, in particular that for CK7 would help in defining the origin of mucin production.
Persistent Identifierhttp://hdl.handle.net/10722/88707
ISSN
2023 Impact Factor: 2.6
2023 SCImago Journal Rankings: 0.951
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorShen, DHen_HK
dc.contributor.authorNg, TYen_HK
dc.contributor.authorUs, Ken_HK
dc.contributor.authorXue, WCen_HK
dc.contributor.authorCheung, ANYen_HK
dc.date.accessioned2010-09-06T09:46:55Z-
dc.date.available2010-09-06T09:46:55Z-
dc.date.issued1998en_HK
dc.identifier.citationInternational Journal Of Gynecology And Obstetrics, 1998, v. 62 n. 2, p. 173-182en_HK
dc.identifier.issn0020-7292en_HK
dc.identifier.urihttp://hdl.handle.net/10722/88707-
dc.description.abstractObjective: To evaluate the origin of pseudomyxoma peritonei (PMP) in Chinese women. Methods: The clinicopathologic features of 15 cases of PMP were reviewed. Immunostaining using antibodies for CK7 and CK20 was performed in the ovarian, appendiceal and peritoneal lesions of these cases. Results: Appendiceal pathology was documented in five cases, including four mucinous cystadenoma and one simple mucocele. Eight ovarian tumors were found, including seven mucinous cystadenocarcinomas of low malignant potential and one mucinous cystadenoma. Synchronous ovarian and appendiceal lesions were discovered in three cases. One patient had adenocarcinoma of the pancreas. The origin of mucin production was not known in four cases with metastatic adenocarcinoma found in two of them. Immunoreactivity for CK20 was demonstrated in the tissues derived from the peritoneum, ovary, appendix and pancreas while only 23% (3 out of 13 women) of the peritoneal lesions and 33% (2 out of 6 women) of the ovarian tumors were immunoreactive for CK7. Conclusions: PMP is a heterogeneous lesion, which may develop from mucinous metaplasia of the peritoneum or from appendiceal, or ovarian lesions. Careful examination of the ovary and appendix with performance of appendectomy is advised in every case of PMP. Immunohistochemical examination of the peritoneal, ovarian or appendiceal lesions using antibodies, in particular that for CK7 would help in defining the origin of mucin production.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijgoen_HK
dc.relation.ispartofInternational Journal of Gynecology and Obstetricsen_HK
dc.rightsInternational Journal of Gynecology & Obstetrics. Copyright © Elsevier Ireland Ltd.en_HK
dc.subjectPseudomyxoma peritonei-
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshImmunohistochemistryen_HK
dc.subject.meshIntermediate Filament Proteins - metabolismen_HK
dc.subject.meshKeratin-20en_HK
dc.subject.meshKeratin-7en_HK
dc.subject.meshKeratins - metabolismen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPeritoneal Neoplasms - chemistry - pathologyen_HK
dc.subject.meshPseudomyxoma Peritonei - metabolism - pathologyen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.titlePseudomyxoma peritonei - A heterogenous diseaseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0020-7292&volume=62&spage=173&epage=182&date=1998&atitle=Pseudomyxoma+peritonei+-+a+heterogenous+diseaseen_HK
dc.identifier.emailCheung, ANY:anycheun@hkucc.hku.hken_HK
dc.identifier.authorityCheung, ANY=rp00542en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0020-7292(98)00095-2en_HK
dc.identifier.pmid9749889-
dc.identifier.scopuseid_2-s2.0-0031853572en_HK
dc.identifier.hkuros42647en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031853572&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume62en_HK
dc.identifier.issue2en_HK
dc.identifier.spage173en_HK
dc.identifier.epage182en_HK
dc.identifier.isiWOS:000075503200008-
dc.publisher.placeIrelanden_HK
dc.identifier.issnl0020-7292-

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