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Article: Portoenterostomy for biliary atresia: long-term survival and prognosis after esophageal variceal bleeding

TitlePortoenterostomy for biliary atresia: long-term survival and prognosis after esophageal variceal bleeding
Authors
KeywordsBile flow
Biliary atresia
Bilirubin
Esophageal bleeding
Kasai operation
Liver failure
Portoenterostomy
Survival rate
Issue Date2004
PublisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurg
Citation
Journal of Pediatric Surgery, 2004, v. 39 n. 1, p. 6-9 How to Cite?
AbstractBackground/Purpose: Portoenterostomy Is The Procedure Of Choice In Patients With Biliary Atresia. The Authors Analyzed The Long-Term Survival Rate And Complications Of The Procedure In Children Operated On At The University Of Hong Kong Medical Centre Between 1979 And 2000. Methods: Seventy-Seven Consecutive Patients Were Analyzed By Retrospective Chart Review. The Patients Were Divided Into Groups According To Postoperative Bile Flow, Decade Of Operation, And Age At Operation. The Data Were Analyzed Statistically. Results: The Overall Actuarial Transplant-Free Survival Rate Was 68% At 10 Years After Operation. For Patients With Poor, Partial, And Good Postoperative Bile Flow, Transplant-Free Survival Rate Was 0%, 22%, And 96%, Respectively (P < .001). Age And Decade Of Operation Were Not Significant Risk Factors. Esophageal Variceal Bleeding Occurred In 13 Patients And Was A Prognostic Indicator For End-Stage Liver Failure (P = .044); The Poor Prognosis Of Patients With Variceal Bleeding, However, Was Related To Poor Or Partial Initial Bile Drainage. Conclusions: The Postoperative Serum Bilirubin Level Is The Most Important Predictor Of Long-Term Survival In Patients With Portoenterostomy For Biliary Atresia. Esophageal Hemorrhage Is Not An Absolute Indication For Urgent Liver Transplantation In Patients With Good Bile Drainage. © 2004 Elsevier Inc. All Rights Reserved.
Persistent Identifierhttp://hdl.handle.net/10722/83478
ISSN
2023 Impact Factor: 2.4
2023 SCImago Journal Rankings: 0.949
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorvan Heurn, LWEen_HK
dc.contributor.authorSaing, Hen_HK
dc.contributor.authorTam, PKHen_HK
dc.date.accessioned2010-09-06T08:41:31Z-
dc.date.available2010-09-06T08:41:31Z-
dc.date.issued2004en_HK
dc.identifier.citationJournal of Pediatric Surgery, 2004, v. 39 n. 1, p. 6-9en_HK
dc.identifier.issn0022-3468en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83478-
dc.description.abstractBackground/Purpose: Portoenterostomy Is The Procedure Of Choice In Patients With Biliary Atresia. The Authors Analyzed The Long-Term Survival Rate And Complications Of The Procedure In Children Operated On At The University Of Hong Kong Medical Centre Between 1979 And 2000. Methods: Seventy-Seven Consecutive Patients Were Analyzed By Retrospective Chart Review. The Patients Were Divided Into Groups According To Postoperative Bile Flow, Decade Of Operation, And Age At Operation. The Data Were Analyzed Statistically. Results: The Overall Actuarial Transplant-Free Survival Rate Was 68% At 10 Years After Operation. For Patients With Poor, Partial, And Good Postoperative Bile Flow, Transplant-Free Survival Rate Was 0%, 22%, And 96%, Respectively (P < .001). Age And Decade Of Operation Were Not Significant Risk Factors. Esophageal Variceal Bleeding Occurred In 13 Patients And Was A Prognostic Indicator For End-Stage Liver Failure (P = .044); The Poor Prognosis Of Patients With Variceal Bleeding, However, Was Related To Poor Or Partial Initial Bile Drainage. Conclusions: The Postoperative Serum Bilirubin Level Is The Most Important Predictor Of Long-Term Survival In Patients With Portoenterostomy For Biliary Atresia. Esophageal Hemorrhage Is Not An Absolute Indication For Urgent Liver Transplantation In Patients With Good Bile Drainage. © 2004 Elsevier Inc. All Rights Reserved.en_US
dc.languageengen_HK
dc.publisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurgen_HK
dc.relation.ispartofJournal of Pediatric Surgeryen_HK
dc.subjectBile flow-
dc.subjectBiliary atresia-
dc.subjectBilirubin-
dc.subjectEsophageal bleeding-
dc.subjectKasai operation-
dc.subjectLiver failure-
dc.subjectPortoenterostomy-
dc.subjectSurvival rate-
dc.titlePortoenterostomy for biliary atresia: long-term survival and prognosis after esophageal variceal bleedingen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-3468&volume=39&issue=1&spage=6&epage=9&date=2004&atitle=Portoenterostomy+for+biliary+atresia:+long-term+survival+and+prognosis+after+esophageal+variceal+bleedingen_HK
dc.identifier.emailSaing, H: saing@hkucc.hku.hken_HK
dc.identifier.emailTam, PKH: paultam@hkucc.hku.hken_HK
dc.identifier.authorityTam, PKH=rp00060en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.jpedsurg.2003.09.019en_US
dc.identifier.pmid14694362-
dc.identifier.scopuseid_2-s2.0-0347662616en_US
dc.identifier.hkuros85942en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0347662616&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume39en_US
dc.identifier.issue1en_US
dc.identifier.spage6en_US
dc.identifier.epage9en_US
dc.identifier.isiWOS:000188259600002-
dc.identifier.issnl0022-3468-

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