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Article: The use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons

TitleThe use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons
Authors
Issue Date2004
PublisherBlackwell Publishing, Inc.
Citation
Dermatologic Surgery, 2004, v. 30 n. 7, p. 987-994 How to Cite?
AbstractBACKGROUND. Pulse dye laser has been used with variable degrees of success in the treatment of hypertrophic scars, and although earlier reports suggested a significant degree of improvement, more recent studies have raised concern about its effectiveness. Furthermore, most previous studies examined its use in patients with light skin types, and the use of pulse dye laser in dark-skinned patients for the treatment of hypertrophic scars is not well established. OBJECTIVE. The objective was to assess the role of pulsed dye laser therapy in the treatment and prevention of hypertrophic scars in Chinese persons. METHODS. Twenty-nine patients (35 scars) who had scars for less than 6 months were recruited into the prevention group, and 27 patients (36 scars) who had scars for more than 6 months were recruited into the treatment arm of the study. Each received pulse dye laser treatment (585 nm, 1.5-msec pulse duration, 5-mm spot size, 7-8 J/cm2) for three to six treatments at 8-week intervals. Half of the scar was treated with the laser and the other half was used as a control. All patients were assessed for subjective improvement with the use of a structured questionnaire and objectively with ultrasonography for thickness and a cutometer for viscoelasticity. Scars were marked on every patient and mapped with a translucent paper at the first appointment to ensure the consistency of location. At the end of the study, 15 patients from the prevention group (15 scars) and 23 patients from the treatment group (34 scars) agreed to return for spectrophotometer assessment. RESULTS. Fifty-four percent of patients in the prevention group and 66% of patients in the treatment group considered their scars to be better or much better. For both groups of patients, there was significant improvement in term of pruritics after laser treatment. For objective assessment, although scar thickness reduced significantly compared to baseline in the treatment group, such change was not significant when changes in the control side were taken into consideration. There was insignificant change in viscoelasticity. Spectrophometer assessment indicated a significant degree of lightening in the treatment group. CONCLUSION. Our study indicated that although there was significant symptomatic improvement, there was an insignificant degree of objective improvement in terms of scar thickness and viscoelasticity in the prevention group compared to the control group. Our findings are in line with several previous controlled studies and contradict the results of several others. Such differences can be due to differences in assessment methodology, laser settings, skin type, and scar location. Suprapurpuric pulsed dye laser should not be considered as the standard of practice for the treatment and prevention of hypertrophic surgical scars especially in the chest in Asians patients.
Persistent Identifierhttp://hdl.handle.net/10722/83465
ISSN
2023 Impact Factor: 2.5
2023 SCImago Journal Rankings: 0.695
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, HHLen_HK
dc.contributor.authorWong, DSYen_HK
dc.contributor.authorHo, WSen_HK
dc.contributor.authorLam, LKen_HK
dc.contributor.authorWei, Wen_HK
dc.date.accessioned2010-09-06T08:41:22Z-
dc.date.available2010-09-06T08:41:22Z-
dc.date.issued2004en_HK
dc.identifier.citationDermatologic Surgery, 2004, v. 30 n. 7, p. 987-994en_HK
dc.identifier.issn1076-0512en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83465-
dc.description.abstractBACKGROUND. Pulse dye laser has been used with variable degrees of success in the treatment of hypertrophic scars, and although earlier reports suggested a significant degree of improvement, more recent studies have raised concern about its effectiveness. Furthermore, most previous studies examined its use in patients with light skin types, and the use of pulse dye laser in dark-skinned patients for the treatment of hypertrophic scars is not well established. OBJECTIVE. The objective was to assess the role of pulsed dye laser therapy in the treatment and prevention of hypertrophic scars in Chinese persons. METHODS. Twenty-nine patients (35 scars) who had scars for less than 6 months were recruited into the prevention group, and 27 patients (36 scars) who had scars for more than 6 months were recruited into the treatment arm of the study. Each received pulse dye laser treatment (585 nm, 1.5-msec pulse duration, 5-mm spot size, 7-8 J/cm2) for three to six treatments at 8-week intervals. Half of the scar was treated with the laser and the other half was used as a control. All patients were assessed for subjective improvement with the use of a structured questionnaire and objectively with ultrasonography for thickness and a cutometer for viscoelasticity. Scars were marked on every patient and mapped with a translucent paper at the first appointment to ensure the consistency of location. At the end of the study, 15 patients from the prevention group (15 scars) and 23 patients from the treatment group (34 scars) agreed to return for spectrophotometer assessment. RESULTS. Fifty-four percent of patients in the prevention group and 66% of patients in the treatment group considered their scars to be better or much better. For both groups of patients, there was significant improvement in term of pruritics after laser treatment. For objective assessment, although scar thickness reduced significantly compared to baseline in the treatment group, such change was not significant when changes in the control side were taken into consideration. There was insignificant change in viscoelasticity. Spectrophometer assessment indicated a significant degree of lightening in the treatment group. CONCLUSION. Our study indicated that although there was significant symptomatic improvement, there was an insignificant degree of objective improvement in terms of scar thickness and viscoelasticity in the prevention group compared to the control group. Our findings are in line with several previous controlled studies and contradict the results of several others. Such differences can be due to differences in assessment methodology, laser settings, skin type, and scar location. Suprapurpuric pulsed dye laser should not be considered as the standard of practice for the treatment and prevention of hypertrophic surgical scars especially in the chest in Asians patients.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing, Inc.en_HK
dc.relation.ispartofDermatologic Surgeryen_HK
dc.titleThe use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese personsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1076-0512&volume=30&spage=987&epage=994&date=2004&atitle=The+use+of+pulsed+dye+laser+for+the+prevention+and+treatment+of+hypertrophic+scars+in+Chinese+personsen_HK
dc.identifier.emailWei, W: hrmswwi@hku.hken_HK
dc.identifier.authorityWei, W=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1524-4725.2004.30303.xen_HK
dc.identifier.pmid15209788-
dc.identifier.scopuseid_2-s2.0-3042703832en_HK
dc.identifier.hkuros92581en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-3042703832&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume30en_HK
dc.identifier.issue7en_HK
dc.identifier.spage987en_HK
dc.identifier.epage994en_HK
dc.identifier.isiWOS:000222205700004-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChan, HHL=24555248900en_HK
dc.identifier.scopusauthoridWong, DSY=7401535906en_HK
dc.identifier.scopusauthoridHo, WS=7402968931en_HK
dc.identifier.scopusauthoridLam, LK=7201984637en_HK
dc.identifier.scopusauthoridWei, W=7403321552en_HK
dc.identifier.issnl1076-0512-

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