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Article: Malignant insulinoma with hepatoid differentiation: A unique case with alpha-fetoprotein production

TitleMalignant insulinoma with hepatoid differentiation: A unique case with alpha-fetoprotein production
Authors
Lam, KYLo, CYWat, MSFan, ST
KeywordsAFP
Hepatoid
Insulinoma
Issue Date2001
PublisherHumana Press, Inc.
Citation
Endocrine Pathology, 2001, v. 12 n. 3, p. 351-354 How to Cite?
DOI: http://dx.doi.org/10.1385/EP:12:3:351
AbstractHepatoid carcinomas are uncommon extra-hepatic neoplasms exhibiting features of hepatocellular carcinoma and they are most frequently described in the stomach. We report a 64-yr-old woman with a malignant insulinoma showing focal hepatoid differentiation and biochemical evidence of alpha-fetoprotein (AFP) production. The current case is the first malignant insulinoma with hepatoid differentiation. Resection of the primary tumor followed by regional embolization was performed. The patient died 22 mo after initial presentation. Thus, the presence of hepatoid differentiation in pancreatic tumor should be noted as the tumor may be associated with elevated AFP. The features of pancreatic hepatoid carcinomas are discussed.
Persistent Identifierhttp://hdl.handle.net/10722/83257
ISSN
1046-3976
2021 Impact Factor: 4.056
2020 SCImago Journal Rankings: 0.990
ISI Accession Number ID
WOS:000173212000011
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLam, KYen_HK
dc.contributor.authorLo, CYen_HK
dc.contributor.authorWat, MSen_HK
dc.contributor.authorFan, STen_HK
dc.date.accessioned2010-09-06T08:38:52Z-
dc.date.available2010-09-06T08:38:52Z-
dc.date.issued2001en_HK
dc.identifier.citationEndocrine Pathology, 2001, v. 12 n. 3, p. 351-354en_HK
dc.identifier.issn1046-3976en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83257-
dc.description.abstractHepatoid carcinomas are uncommon extra-hepatic neoplasms exhibiting features of hepatocellular carcinoma and they are most frequently described in the stomach. We report a 64-yr-old woman with a malignant insulinoma showing focal hepatoid differentiation and biochemical evidence of alpha-fetoprotein (AFP) production. The current case is the first malignant insulinoma with hepatoid differentiation. Resection of the primary tumor followed by regional embolization was performed. The patient died 22 mo after initial presentation. Thus, the presence of hepatoid differentiation in pancreatic tumor should be noted as the tumor may be associated with elevated AFP. The features of pancreatic hepatoid carcinomas are discussed.en_HK
dc.languageengen_HK
dc.publisherHumana Press, Inc.en_HK
dc.relation.ispartofEndocrine Pathologyen_HK
dc.subjectAFPen_HK
dc.subjectHepatoiden_HK
dc.subjectInsulinomaen_HK
dc.titleMalignant insulinoma with hepatoid differentiation: A unique case with alpha-fetoprotein productionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1046-3976&volume=12&issue=3&spage=351&epage=354&date=2001&atitle=Malignant+insulinoma+with+hepatoid+differentiation:+a+unique+case+with+alpha-fetoprotein+productionen_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1385/EP:12:3:351en_HK
dc.identifier.pmid11740056-
dc.identifier.scopuseid_2-s2.0-0035691132en_HK
dc.identifier.hkuros69787en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035691132&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume12en_HK
dc.identifier.issue3en_HK
dc.identifier.spage351en_HK
dc.identifier.epage354en_HK
dc.identifier.isiWOS:000173212000011-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLam, KY=7403657165en_HK
dc.identifier.scopusauthoridLo, CY=36151700700en_HK
dc.identifier.scopusauthoridWat, MS=6603247639en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.issnl1046-3976-

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