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Article: Mortality of twins and singletons by gestational age: A varying-coefficient approach

TitleMortality of twins and singletons by gestational age: A varying-coefficient approach
Authors
KeywordsGestational age
Infant mortality
Pregnancy
Twins
Issue Date2000
PublisherOxford University Press. The Journal's web site is located at http://aje.oxfordjournals.org/
Citation
American Journal Of Epidemiology, 2000, v. 152 n. 12, p. 1107-1116 How to Cite?
AbstractThis study used data from the Swedish Medical Birth Registry between 1982 and 1995 to address the question of whether there is higher mortality in twins in relation to singletons of the same gestational age and to examine the optimal gestational age range for twins. A 'varying-coefficient approach' was adopted to estimate the gestational age-specific relative and absolute risks of mortality in twins and singletons, adjusting for size at birth and risk factors of short gestational duration. The models showed that twins born between 29 and 37 weeks of gestation had lower mortality than did singletons of the same gestational age. Twins born at older gestational age had higher mortality than did their singleton counterparts, because longer gestational duration was more advantageous to singletons than to twins. Without adjustment for size at birth, there was an upturn of mortality in twins born after 38 weeks. It is postulated that twins have better health than singletons initially, but they could not enjoy the benefit of a longer gestational duration as much as singletons could. The optimal gestational age for twins appeared to be 37-39 weeks according to neonatal and infant mortality.
Persistent Identifierhttp://hdl.handle.net/10722/80046
ISSN
2023 Impact Factor: 5.0
2023 SCImago Journal Rankings: 0.837
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, YBen_HK
dc.contributor.authorYip, Pen_HK
dc.contributor.authorKarlberg, Jen_HK
dc.date.accessioned2010-09-06T08:01:45Z-
dc.date.available2010-09-06T08:01:45Z-
dc.date.issued2000en_HK
dc.identifier.citationAmerican Journal Of Epidemiology, 2000, v. 152 n. 12, p. 1107-1116en_HK
dc.identifier.issn0002-9262en_HK
dc.identifier.urihttp://hdl.handle.net/10722/80046-
dc.description.abstractThis study used data from the Swedish Medical Birth Registry between 1982 and 1995 to address the question of whether there is higher mortality in twins in relation to singletons of the same gestational age and to examine the optimal gestational age range for twins. A 'varying-coefficient approach' was adopted to estimate the gestational age-specific relative and absolute risks of mortality in twins and singletons, adjusting for size at birth and risk factors of short gestational duration. The models showed that twins born between 29 and 37 weeks of gestation had lower mortality than did singletons of the same gestational age. Twins born at older gestational age had higher mortality than did their singleton counterparts, because longer gestational duration was more advantageous to singletons than to twins. Without adjustment for size at birth, there was an upturn of mortality in twins born after 38 weeks. It is postulated that twins have better health than singletons initially, but they could not enjoy the benefit of a longer gestational duration as much as singletons could. The optimal gestational age for twins appeared to be 37-39 weeks according to neonatal and infant mortality.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://aje.oxfordjournals.org/en_HK
dc.relation.ispartofAmerican Journal of Epidemiologyen_HK
dc.rightsAmerican Journal of Epidemiology. Copyright © Oxford University Press.en_HK
dc.subjectGestational ageen_HK
dc.subjectInfant mortalityen_HK
dc.subjectPregnancyen_HK
dc.subjectTwinsen_HK
dc.titleMortality of twins and singletons by gestational age: A varying-coefficient approachen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0002-9262&volume=152&issue=12&spage=1107&epage=1116&date=2000&atitle=Mortality+of+Twins+and+Singletons+by+Gestational+Age:+A+Varying-Coefficient+Approachen_HK
dc.identifier.emailYip, P: sfpyip@hku.hken_HK
dc.identifier.emailKarlberg, J: jpekarl@hkucc.hku.hken_HK
dc.identifier.authorityYip, P=rp00596en_HK
dc.identifier.authorityKarlberg, J=rp00400en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/aje/152.12.1107en_HK
dc.identifier.pmid11130615-
dc.identifier.scopuseid_2-s2.0-0034671773en_HK
dc.identifier.hkuros56358en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034671773&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume152en_HK
dc.identifier.issue12en_HK
dc.identifier.spage1107en_HK
dc.identifier.epage1116en_HK
dc.identifier.isiWOS:000165854200001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridCheung, YB=7202111441en_HK
dc.identifier.scopusauthoridYip, P=7102503720en_HK
dc.identifier.scopusauthoridKarlberg, J=7005218406en_HK
dc.identifier.issnl0002-9262-

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