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Article: Proton-density-weighted spinal fMRI with sensorimotor stimulation at 0.2 T

TitleProton-density-weighted spinal fMRI with sensorimotor stimulation at 0.2 T
Authors
KeywordsBOLD
fMRI
MRI
Proton density
SEEP
Sensorimotor and spinal cord
Issue Date2006
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ynimg
Citation
Neuroimage, 2006, v. 29 n. 3, p. 995-999 How to Cite?
AbstractProton-density-weighted fMRI at low field (0.2 T) was carried out in the cervical spinal cord of healthy volunteers in this study to examine the feasibility of detecting proton density alteration accompanying activation in the spinal cord. Subjects were asked to grip both hands simultaneously, providing sensorimotor simulation for spinal fMRI. Over 70% subjects recruited had activation localized at C6-C7 spinal levels with discrete activation detected in both the anterior and posterior horns of the cervical spinal cord, and the average fractional signal change was 4.06%. The 0.2 T low magnetic field and the 24 ms short TE used in this study diminished the BOLD effect to a negligible level, thus the observed signal change was believed to be mainly attributable to proton density increase during neuronal stimulation. Our results suggested the existence of task-driven proton density change in the cervical spinal cord. © 2005 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/79619
ISSN
2023 Impact Factor: 4.7
2023 SCImago Journal Rankings: 2.436
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, MCen_HK
dc.contributor.authorWong, KKen_HK
dc.contributor.authorLi, Gen_HK
dc.contributor.authorLai, Sen_HK
dc.contributor.authorYang, ESen_HK
dc.contributor.authorHu, Yen_HK
dc.contributor.authorLuk, KDen_HK
dc.date.accessioned2010-09-06T07:56:42Z-
dc.date.available2010-09-06T07:56:42Z-
dc.date.issued2006en_HK
dc.identifier.citationNeuroimage, 2006, v. 29 n. 3, p. 995-999en_HK
dc.identifier.issn1053-8119en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79619-
dc.description.abstractProton-density-weighted fMRI at low field (0.2 T) was carried out in the cervical spinal cord of healthy volunteers in this study to examine the feasibility of detecting proton density alteration accompanying activation in the spinal cord. Subjects were asked to grip both hands simultaneously, providing sensorimotor simulation for spinal fMRI. Over 70% subjects recruited had activation localized at C6-C7 spinal levels with discrete activation detected in both the anterior and posterior horns of the cervical spinal cord, and the average fractional signal change was 4.06%. The 0.2 T low magnetic field and the 24 ms short TE used in this study diminished the BOLD effect to a negligible level, thus the observed signal change was believed to be mainly attributable to proton density increase during neuronal stimulation. Our results suggested the existence of task-driven proton density change in the cervical spinal cord. © 2005 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ynimgen_HK
dc.relation.ispartofNeuroImageen_HK
dc.subjectBOLDen_HK
dc.subjectfMRIen_HK
dc.subjectMRIen_HK
dc.subjectProton densityen_HK
dc.subjectSEEPen_HK
dc.subjectSensorimotor and spinal corden_HK
dc.titleProton-density-weighted spinal fMRI with sensorimotor stimulation at 0.2 Ten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1053-8119&volume=29&spage=995&epage=999&date=2006&atitle=Proton-density-weighted+spinal+fMRI+with+sensorimotor+stimulation+at+0.2+Ten_HK
dc.identifier.emailYang, ES:esyang@hkueee.hku.hken_HK
dc.identifier.emailHu, Y:yhud@hku.hken_HK
dc.identifier.emailLuk, KD:hcm21000@hku.hken_HK
dc.identifier.authorityYang, ES=rp00199en_HK
dc.identifier.authorityHu, Y=rp00432en_HK
dc.identifier.authorityLuk, KD=rp00333en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.neuroimage.2005.08.011en_HK
dc.identifier.pmid16140548-
dc.identifier.scopuseid_2-s2.0-31144446078en_HK
dc.identifier.hkuros124941en_HK
dc.identifier.hkuros112263-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-31144446078&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume29en_HK
dc.identifier.issue3en_HK
dc.identifier.spage995en_HK
dc.identifier.epage999en_HK
dc.identifier.isiWOS:000235227400031-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridNg, MC=7202076279en_HK
dc.identifier.scopusauthoridWong, KK=35222708000en_HK
dc.identifier.scopusauthoridLi, G=35767974200en_HK
dc.identifier.scopusauthoridLai, S=7402937083en_HK
dc.identifier.scopusauthoridYang, ES=7202021229en_HK
dc.identifier.scopusauthoridHu, Y=7407116091en_HK
dc.identifier.scopusauthoridLuk, KD=7201921573en_HK
dc.identifier.issnl1053-8119-

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