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Article: Spontaneous pneumomediastinum in patients with severe acute respiratory syndrome

TitleSpontaneous pneumomediastinum in patients with severe acute respiratory syndrome
Authors
KeywordsComplication
Coronavirus
Pneumomediastinum
Pneumothorax
Severe acute respiratory syndrome
Issue Date2004
PublisherEuropean Respiratory Society. The Journal's web site is located at http://erj.ersjournals.com
Citation
European Respiratory Journal, 2004, v. 23 n. 6, p. 802-804 How to Cite?
AbstractSpontaneous pneumomediastinum (SP) unrelated to assisted ventilation is a newly recognised complication of severe acute respiratory syndrome (SARS). The objective of the present study was to examine the incidence, risk factors and the outcomes of SP in a cohort of SARS victims from a community outbreak. Data were retrieved from a prospectively collected database of virologically confirmed SARS patients. One hundred and twelve cases were analysable, with 13 patients developing SP (11.6%) at a mean±SD of 19.6±4.6 days from symptom onset. Peak lactate dehydrogenase level was associated with the development of SP. SP was associated with increased intubation and a trend towards death. Drainage was required in five cases. For patients who survived, the SP and/or the associated pneumothoraces took a median of 28 days (interquartile range: 15-45 days) to resolve completely. In conclusion, spontaneous pneumomediastinum appeared to be a frequent complication of severe acute respiratory syndrome. Further research is needed to investigate its pathogenesis. © ERS Journals Ltd 2004.
Persistent Identifierhttp://hdl.handle.net/10722/79177
ISSN
2023 Impact Factor: 16.6
2023 SCImago Journal Rankings: 3.810
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChu, CMen_HK
dc.contributor.authorLeung, YYen_HK
dc.contributor.authorHui, JYHen_HK
dc.contributor.authorHung, IFNen_HK
dc.contributor.authorChan, VLen_HK
dc.contributor.authorLeung, WSen_HK
dc.contributor.authorLaw, WSen_HK
dc.contributor.authorChan, CSen_HK
dc.contributor.authorChan, KSen_HK
dc.contributor.authorYuen, KYen_HK
dc.date.accessioned2010-09-06T07:51:31Z-
dc.date.available2010-09-06T07:51:31Z-
dc.date.issued2004en_HK
dc.identifier.citationEuropean Respiratory Journal, 2004, v. 23 n. 6, p. 802-804en_HK
dc.identifier.issn0903-1936en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79177-
dc.description.abstractSpontaneous pneumomediastinum (SP) unrelated to assisted ventilation is a newly recognised complication of severe acute respiratory syndrome (SARS). The objective of the present study was to examine the incidence, risk factors and the outcomes of SP in a cohort of SARS victims from a community outbreak. Data were retrieved from a prospectively collected database of virologically confirmed SARS patients. One hundred and twelve cases were analysable, with 13 patients developing SP (11.6%) at a mean±SD of 19.6±4.6 days from symptom onset. Peak lactate dehydrogenase level was associated with the development of SP. SP was associated with increased intubation and a trend towards death. Drainage was required in five cases. For patients who survived, the SP and/or the associated pneumothoraces took a median of 28 days (interquartile range: 15-45 days) to resolve completely. In conclusion, spontaneous pneumomediastinum appeared to be a frequent complication of severe acute respiratory syndrome. Further research is needed to investigate its pathogenesis. © ERS Journals Ltd 2004.en_HK
dc.languageengen_HK
dc.publisherEuropean Respiratory Society. The Journal's web site is located at http://erj.ersjournals.comen_HK
dc.relation.ispartofEuropean Respiratory Journalen_HK
dc.subjectComplicationen_HK
dc.subjectCoronavirusen_HK
dc.subjectPneumomediastinumen_HK
dc.subjectPneumothoraxen_HK
dc.subjectSevere acute respiratory syndromeen_HK
dc.subject.meshAdulten_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHong Kongen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMediastinal Emphysema - etiology - radiographyen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshSevere Acute Respiratory Syndrome - complications - drug therapy - radiographyen_HK
dc.subject.meshStatistics, Nonparametricen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.titleSpontaneous pneumomediastinum in patients with severe acute respiratory syndromeen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0903-1936&volume=23&issue=6&spage=802&epage=4&date=2004&atitle=Spontaneous+pneumomediastinum+in+patients+with+severe+acute+respiratory+syndromeen_HK
dc.identifier.emailHung, IFN:ivanhung@hkucc.hku.hken_HK
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_HK
dc.identifier.authorityHung, IFN=rp00508en_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1183/09031936.04.00096404-
dc.identifier.pmid15218989-
dc.identifier.scopuseid_2-s2.0-3042555360en_HK
dc.identifier.hkuros94833en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-3042555360&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume23en_HK
dc.identifier.issue6en_HK
dc.identifier.spage802en_HK
dc.identifier.epage804en_HK
dc.identifier.isiWOS:000221996500005-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridChu, CM=7404345558en_HK
dc.identifier.scopusauthoridLeung, YY=7201463874en_HK
dc.identifier.scopusauthoridHui, JYH=35080369800en_HK
dc.identifier.scopusauthoridHung, IFN=7006103457en_HK
dc.identifier.scopusauthoridChan, VL=7202655014en_HK
dc.identifier.scopusauthoridLeung, WS=7201504471en_HK
dc.identifier.scopusauthoridLaw, WS=54885137800en_HK
dc.identifier.scopusauthoridChan, CS=8791643700en_HK
dc.identifier.scopusauthoridChan, KS=7406031627en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK
dc.identifier.issnl0903-1936-

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