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Article: Viral loads in clinical specimens and SARS manifestations

TitleViral loads in clinical specimens and SARS manifestations
Authors
Hung, IFNCheng, VCCWu, AKLTang, BSFChan, KHChu, CMWong, MMLHui, WTPoon, LLMTse, DMWChan, KSWoo, PCYLau, SKPPeiris, JSMYuen, KY
Issue Date2004
PublisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm
Citation
Emerging Infectious Diseases, 2004, v. 10 n. 9, p. 1550-1557 How to Cite?
DOI: http://dx.doi.org/10.3201/eid1009.040058
AbstractA retrospective viral load study was performed on clinical specimens from 154 patients with laboratory-confirmed severe acute respiratory syndrome (SARS); the specimens were prospectively collected during patients' illness, Viral load in nasopharyngeal aspirates (n = 142) from day 10 to day 15 after onset of symptoms was associated with oxygen desaturation, mechanical ventilation, diarrhea, hepatic dysfunction, and death. Serum viral load (n = 53) was associated with oxygen desaturation, mechanical ventilation, and death. Stool viral load (n = 94) was associated with diarrhea, and urine viral load (n = 111) was associated with 'abnormal urinalysis results. Viral replications at different sites are important in the pathogenesis of clinical and laboratory abnormalities of SARS.
Persistent Identifierhttp://hdl.handle.net/10722/79173
ISSN
1080-6040
2021 Impact Factor: 16.126
2020 SCImago Journal Rankings: 2.540
PubMed Central ID
PMC3320271
ISI Accession Number ID
WOS:000223740200005
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorHung, IFNen_HK
dc.contributor.authorCheng, VCCen_HK
dc.contributor.authorWu, AKLen_HK
dc.contributor.authorTang, BSFen_HK
dc.contributor.authorChan, KHen_HK
dc.contributor.authorChu, CMen_HK
dc.contributor.authorWong, MMLen_HK
dc.contributor.authorHui, WTen_HK
dc.contributor.authorPoon, LLMen_HK
dc.contributor.authorTse, DMWen_HK
dc.contributor.authorChan, KSen_HK
dc.contributor.authorWoo, PCYen_HK
dc.contributor.authorLau, SKPen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorYuen, KYen_HK
dc.date.accessioned2010-09-06T07:51:28Z-
dc.date.available2010-09-06T07:51:28Z-
dc.date.issued2004en_HK
dc.identifier.citationEmerging Infectious Diseases, 2004, v. 10 n. 9, p. 1550-1557en_HK
dc.identifier.issn1080-6040en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79173-
dc.description.abstractA retrospective viral load study was performed on clinical specimens from 154 patients with laboratory-confirmed severe acute respiratory syndrome (SARS); the specimens were prospectively collected during patients' illness, Viral load in nasopharyngeal aspirates (n = 142) from day 10 to day 15 after onset of symptoms was associated with oxygen desaturation, mechanical ventilation, diarrhea, hepatic dysfunction, and death. Serum viral load (n = 53) was associated with oxygen desaturation, mechanical ventilation, and death. Stool viral load (n = 94) was associated with diarrhea, and urine viral load (n = 111) was associated with 'abnormal urinalysis results. Viral replications at different sites are important in the pathogenesis of clinical and laboratory abnormalities of SARS.en_HK
dc.languageengen_HK
dc.publisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htmen_HK
dc.relation.ispartofEmerging Infectious Diseasesen_HK
dc.subject.meshSARS Virus - isolation and purification-
dc.subject.meshSevere Acute Respiratory Syndrome - blood - physiopathology - urine - virology-
dc.subject.meshViral Load-
dc.subject.meshNasopharynx/virology-
dc.subject.meshDisease Outbreaks-
dc.titleViral loads in clinical specimens and SARS manifestationsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1080-6040&volume=10&issue=9&spage=1550&epage=1557&date=2004&atitle=Viral+loads+in+clinical+specimens+and+SARS+manifestationsen_HK
dc.identifier.emailHung, IFN: ivanhung@hkucc.hku.hken_HK
dc.identifier.emailPoon, LLM: llmpoon@hkucc.hku.hken_HK
dc.identifier.emailWoo, PCY: pcywoo@hkucc.hku.hken_HK
dc.identifier.emailLau, SKP: skplau@hkucc.hku.hken_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.emailYuen, KY: kyyuen@hkucc.hku.hken_HK
dc.identifier.authorityHung, IFN=rp00508en_HK
dc.identifier.authorityPoon, LLM=rp00484en_HK
dc.identifier.authorityWoo, PCY=rp00430en_HK
dc.identifier.authorityLau, SKP=rp00486en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3201/eid1009.040058-
dc.identifier.pmid15498155-
dc.identifier.pmcidPMC3320271-
dc.identifier.scopuseid_2-s2.0-4444220095en_HK
dc.identifier.hkuros161496en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-4444220095&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume10en_HK
dc.identifier.issue9en_HK
dc.identifier.spage1550en_HK
dc.identifier.epage1557en_HK
dc.identifier.isiWOS:000223740200005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHung, IFN=7006103457en_HK
dc.identifier.scopusauthoridCheng, VCC=23670479400en_HK
dc.identifier.scopusauthoridWu, AKL=7402998681en_HK
dc.identifier.scopusauthoridTang, BSF=8908243000en_HK
dc.identifier.scopusauthoridChan, KH=7406034307en_HK
dc.identifier.scopusauthoridChu, CM=7404345558en_HK
dc.identifier.scopusauthoridWong, MML=9278575000en_HK
dc.identifier.scopusauthoridHui, WT=7103196480en_HK
dc.identifier.scopusauthoridPoon, LLM=7005441747en_HK
dc.identifier.scopusauthoridTse, DMW=7101916534en_HK
dc.identifier.scopusauthoridChan, KS=7406031627en_HK
dc.identifier.scopusauthoridWoo, PCY=7201801340en_HK
dc.identifier.scopusauthoridLau, SKP=7401596211en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK
dc.identifier.issnl1080-6040-

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