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Article: Aetiology: Koch's postulates fulfilled for SARS virus

TitleAetiology: Koch's postulates fulfilled for SARS virus
Authors
Fouchier, RAMKuiken, TSchutten, Mvan Amerongen, Gvan Doornum, GJJvan den Hoogen, BGPeiris, MLim, WStohr, KOsterhaus, ADME
Issue Date2003
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nature
Citation
Nature, 2003, v. 423 n. 6937, p. 240 How to Cite?
DOI: http://dx.doi.org/10.1038/423240a
AbstractSevere acute respiratory syndrome (SARS) has recently emerged as a new human disease, resulting globally in 435 deaths from 6,234 probable cases (as of 3 May 2003). Here we provide proof from experimental infection of cynomolgus macaques (Macaca fascicularis) that the newly discovered SARS-associated coronavirus (SCV) is the aetiological agent of this disease. Our understanding of the aetiology of SARS will expedite the development of diagnostic tests, antiviral therapies and vaccines, and may allow a more concise case definition for this emerging disease.
Persistent Identifierhttp://hdl.handle.net/10722/79002
ISSN
0028-0836
2021 Impact Factor: 69.504
2020 SCImago Journal Rankings: 15.993
ISI Accession Number ID
WOS:000182853100032
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorFouchier, RAM-
dc.contributor.authorKuiken, T-
dc.contributor.authorSchutten, M-
dc.contributor.authorvan Amerongen, G-
dc.contributor.authorvan Doornum, GJJ-
dc.contributor.authorvan den Hoogen, BG-
dc.contributor.authorPeiris, M-
dc.contributor.authorLim, W-
dc.contributor.authorStohr, K-
dc.contributor.authorOsterhaus, ADME-
dc.date.accessioned2010-09-06T07:49:24Z-
dc.date.available2010-09-06T07:49:24Z-
dc.date.issued2003-
dc.identifier.citationNature, 2003, v. 423 n. 6937, p. 240-
dc.identifier.issn0028-0836-
dc.identifier.urihttp://hdl.handle.net/10722/79002-
dc.description.abstractSevere acute respiratory syndrome (SARS) has recently emerged as a new human disease, resulting globally in 435 deaths from 6,234 probable cases (as of 3 May 2003). Here we provide proof from experimental infection of cynomolgus macaques (Macaca fascicularis) that the newly discovered SARS-associated coronavirus (SCV) is the aetiological agent of this disease. Our understanding of the aetiology of SARS will expedite the development of diagnostic tests, antiviral therapies and vaccines, and may allow a more concise case definition for this emerging disease.-
dc.languageeng-
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nature-
dc.relation.ispartofNature-
dc.subject.meshDisease Models, Animal-
dc.subject.meshMacaca fascicularis - immunology - virology-
dc.subject.meshPharynx - virology-
dc.subject.meshSARS Virus - immunology - isolation & purification - pathogenicity - physiology-
dc.subject.meshSevere Acute Respiratory Syndrome - complications - immunology - pathology - virology-
dc.titleAetiology: Koch's postulates fulfilled for SARS virus-
dc.typeArticle-
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0028-0836&volume=423&issue=6937&spage=240&epage=&date=2003&atitle=Aetiology:+Koch%27s+postulates+fulfilled+for+SARS+virusen_HK
dc.identifier.emailPeiris, M: malik@hkucc.hku.hk-
dc.identifier.authorityPeiris, M=rp00410-
dc.identifier.doi10.1038/423240a-
dc.identifier.pmid12748632-
dc.identifier.scopuseid_2-s2.0-0038011859-
dc.identifier.hkuros83203-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0038011859&selection=ref&src=s&origin=recordpage-
dc.identifier.volume423-
dc.identifier.issue6937-
dc.identifier.spage240-
dc.identifier.epage240-
dc.identifier.isiWOS:000182853100032-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl0028-0836-

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