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Article: Cerebral infarcts complicating tuberculous meningitis

TitleCerebral infarcts complicating tuberculous meningitis
Authors
KeywordsCerebral infarction
Corticosteroid
Lacunar infarct
Large artery infarct
Tuberculous meningitis
Issue Date2005
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/CED
Citation
Cerebrovascular Diseases, 2005, v. 19 n. 6, p. 391-395 How to Cite?
AbstractCerebral infarction (CI) is a serious complication of tuberculous meningitis (TBM). It can be asymptomatic or symptomatic, causing stroke. We studied 40 TBM patients. All had initial CT brain scan, CT/MRI brain scan 3 months later and urgent CT brain scan for deterioration. CI was classified into lacunar infarction (LI) or large artery infarction (LAI). Twelve (30%) had CI, in 9 (23%) it was symptomatic and in 3 (8%) silent. Seven (58%) had LAI ± LI. Eight (67%) had multiple CI. Two died from brainstem CI and 6 were dependent at 1 year. Patients with LAI might develop posterior circulation CI more frequently than those with LI only. CI is a common complication of TBM locally, with LAI and multiple CI being common. Two thirds of TBM patients complicated by CI had poor prognosis despite adjunctive dexamethasone treatment. Copyright © 2005 S. Karger AG.
Persistent Identifierhttp://hdl.handle.net/10722/78541
ISSN
2023 Impact Factor: 2.2
2023 SCImago Journal Rankings: 0.700
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, KHen_HK
dc.contributor.authorCheung, RTFen_HK
dc.contributor.authorLee, Ren_HK
dc.contributor.authorMak, Wen_HK
dc.contributor.authorHo, SLen_HK
dc.date.accessioned2010-09-06T07:44:01Z-
dc.date.available2010-09-06T07:44:01Z-
dc.date.issued2005en_HK
dc.identifier.citationCerebrovascular Diseases, 2005, v. 19 n. 6, p. 391-395en_HK
dc.identifier.issn1015-9770en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78541-
dc.description.abstractCerebral infarction (CI) is a serious complication of tuberculous meningitis (TBM). It can be asymptomatic or symptomatic, causing stroke. We studied 40 TBM patients. All had initial CT brain scan, CT/MRI brain scan 3 months later and urgent CT brain scan for deterioration. CI was classified into lacunar infarction (LI) or large artery infarction (LAI). Twelve (30%) had CI, in 9 (23%) it was symptomatic and in 3 (8%) silent. Seven (58%) had LAI ± LI. Eight (67%) had multiple CI. Two died from brainstem CI and 6 were dependent at 1 year. Patients with LAI might develop posterior circulation CI more frequently than those with LI only. CI is a common complication of TBM locally, with LAI and multiple CI being common. Two thirds of TBM patients complicated by CI had poor prognosis despite adjunctive dexamethasone treatment. Copyright © 2005 S. Karger AG.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/CEDen_HK
dc.relation.ispartofCerebrovascular Diseasesen_HK
dc.rightsCerebrovascular Diseases. Copyright © S Karger AG.en_HK
dc.subjectCerebral infarction-
dc.subjectCorticosteroid-
dc.subjectLacunar infarct-
dc.subjectLarge artery infarct-
dc.subjectTuberculous meningitis-
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshAnti-Inflammatory Agents - therapeutic useen_HK
dc.subject.meshCerebral Infarction - etiology - radiographyen_HK
dc.subject.meshDexamethasone - therapeutic useen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMagnetic Resonance Imagingen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPrognosisen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.subject.meshTreatment Outcomeen_HK
dc.subject.meshTuberculosis, Meningeal - complications - drug therapy - radiographyen_HK
dc.titleCerebral infarcts complicating tuberculous meningitisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1015-9770&volume=19&issue=6&spage=391&epage=395&date=2005&atitle=Cerebral+infarcts+complicating+tuberculous+meningitisen_HK
dc.identifier.emailCheung, RTF:rtcheung@hku.hken_HK
dc.identifier.emailHo, SL:slho@hku.hken_HK
dc.identifier.authorityCheung, RTF=rp00434en_HK
dc.identifier.authorityHo, SL=rp00240en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000085568en_HK
dc.identifier.pmid15863982-
dc.identifier.scopuseid_2-s2.0-21344447963en_HK
dc.identifier.hkuros99208en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-21344447963&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume19en_HK
dc.identifier.issue6en_HK
dc.identifier.spage391en_HK
dc.identifier.epage395en_HK
dc.identifier.isiWOS:000230134000006-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridChan, KH=7406034963en_HK
dc.identifier.scopusauthoridCheung, RTF=7202397498en_HK
dc.identifier.scopusauthoridLee, R=7408203830en_HK
dc.identifier.scopusauthoridMak, W=22948344000en_HK
dc.identifier.scopusauthoridHo, SL=25959633500en_HK
dc.identifier.issnl1015-9770-

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