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Article: Age-related differences in response regulation as revealed by functional MRI

TitleAge-related differences in response regulation as revealed by functional MRI
Authors
KeywordsAgeing
Functional magnetic resonance imaging
Habitual response
Inhibition
Response regulation
Issue Date2006
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainres
Citation
Brain Research, 2006, v. 1076 n. 1, p. 171-176 How to Cite?
AbstractThis fMRI study studied age-related differences in neural activities during response regulation. Twenty-one male participants from two age groups, a younger group and an older group (mean ages: 29.9 and 65.2 years, respectively), were scanned while performing a task with response compatibility manipulation. They were presented with a sequence of arrowheads that pointed either upward or downward. In the "Response Compatible" condition, they were required to press an up or a down button consistent with the direction of the arrowhead. In the "Response Incompatible" condition, they were required to press the button opposite to the arrowhead direction so that an upward arrow should elicit a down response, and vice versa. Findings showed age-related differences in response regulation in several brain regions, including the right frontal, the right cingulate, and the left inferior parietal cortexes. The findings suggested a higher level of neural activity in the right prefrontal and left inferior parietal regions during response regulation for the older adults than for the younger adults. © 2006 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/76701
ISSN
2023 Impact Factor: 2.7
2023 SCImago Journal Rankings: 0.832
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLee, TMCen_HK
dc.contributor.authorZhang, JXen_HK
dc.contributor.authorChan, CCHen_HK
dc.contributor.authorYuen, KSLen_HK
dc.contributor.authorChu, LWen_HK
dc.contributor.authorCheung, RTFen_HK
dc.contributor.authorChan, YSen_HK
dc.contributor.authorFox, PTen_HK
dc.contributor.authorGao, JHen_HK
dc.date.accessioned2010-09-06T07:24:01Z-
dc.date.available2010-09-06T07:24:01Z-
dc.date.issued2006en_HK
dc.identifier.citationBrain Research, 2006, v. 1076 n. 1, p. 171-176en_HK
dc.identifier.issn0006-8993en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76701-
dc.description.abstractThis fMRI study studied age-related differences in neural activities during response regulation. Twenty-one male participants from two age groups, a younger group and an older group (mean ages: 29.9 and 65.2 years, respectively), were scanned while performing a task with response compatibility manipulation. They were presented with a sequence of arrowheads that pointed either upward or downward. In the "Response Compatible" condition, they were required to press an up or a down button consistent with the direction of the arrowhead. In the "Response Incompatible" condition, they were required to press the button opposite to the arrowhead direction so that an upward arrow should elicit a down response, and vice versa. Findings showed age-related differences in response regulation in several brain regions, including the right frontal, the right cingulate, and the left inferior parietal cortexes. The findings suggested a higher level of neural activity in the right prefrontal and left inferior parietal regions during response regulation for the older adults than for the younger adults. © 2006 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainresen_HK
dc.relation.ispartofBrain Researchen_HK
dc.rightsBrain Research. Copyright © Elsevier BV.en_HK
dc.subjectAgeingen_HK
dc.subjectFunctional magnetic resonance imagingen_HK
dc.subjectHabitual responseen_HK
dc.subjectInhibitionen_HK
dc.subjectResponse regulationen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAging - physiologyen_HK
dc.subject.meshAnalysis of Varianceen_HK
dc.subject.meshBrain - blood supply - physiologyen_HK
dc.subject.meshBrain Mappingen_HK
dc.subject.meshHumansen_HK
dc.subject.meshImage Processing, Computer-Assisted - methodsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNeuropsychological Tests - statistics & numerical dataen_HK
dc.subject.meshOxygen - blooden_HK
dc.subject.meshPsychomotor Performance - physiologyen_HK
dc.subject.meshReaction Time - physiologyen_HK
dc.titleAge-related differences in response regulation as revealed by functional MRIen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0006-8993&volume=1076&issue=1&spage=171&epage=176&date=2006&atitle=Age-related+differences+in+response+regulation+as+revealed+by+functional+MRIen_HK
dc.identifier.emailLee, TMC: tmclee@hku.hken_HK
dc.identifier.emailCheung, RTF: rtcheung@hku.hken_HK
dc.identifier.emailChan, YS: yschan@hkucc.hku.hken_HK
dc.identifier.authorityLee, TMC=rp00564en_HK
dc.identifier.authorityCheung, RTF=rp00434en_HK
dc.identifier.authorityChan, YS=rp00318en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.brainres.2005.12.124en_HK
dc.identifier.pmid16476418-
dc.identifier.scopuseid_2-s2.0-33644851853en_HK
dc.identifier.hkuros115107en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33644851853&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume1076en_HK
dc.identifier.issue1en_HK
dc.identifier.spage171en_HK
dc.identifier.epage176en_HK
dc.identifier.isiWOS:000236692500019-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridLee, TMC=7501437381en_HK
dc.identifier.scopusauthoridZhang, JX=55041308500en_HK
dc.identifier.scopusauthoridChan, CCH=16244174500en_HK
dc.identifier.scopusauthoridYuen, KSL=7202333396en_HK
dc.identifier.scopusauthoridChu, LW=7202236665en_HK
dc.identifier.scopusauthoridCheung, RTF=7202397498en_HK
dc.identifier.scopusauthoridChan, YS=7403676627en_HK
dc.identifier.scopusauthoridFox, PT=7402680249en_HK
dc.identifier.scopusauthoridGao, JH=7404475674en_HK
dc.identifier.issnl0006-8993-

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