In vitro fluoride release from aesthetic restorative materials following recharging with APF gel

Abstract

In this in vitro study, the fluoride ion release from three more-viscous conventional glass ionomer cements (GICs) - ChemFlex, Fuji IX GP, Ionofil Molar - four polyacid-modified resin composites (compomers) - Dyract AP, Compoglass F, Freedom, F2000 - and a hybrid resin composite - Ariston pHc - were compared. The amounts of fluoride release from 3x2.7mm specimens were measured over six weeks using a fluoride ion-selective electrode. After six weeks, the specimens were recharged with 2ml of 1.23 per cent acidulated phosphate fluoride (APF) gel for four minutes. The recharged specimens were then assessed for the amounts of fluoride release over another six weeks. Statistical analyses were performed using one-way and repeated measures ANOVA. The GICs and Compoglass F showed significantly higher initial fluoride release rates during the first two days (p<0.05). After the first two days, fluoride release rates from all materials dropped quickly and became essentially stabilized within three-five weeks, in an exponential mode. The recharging of the specimens with APF gel caused a brief, but significant, increase in fluoride release for all materials (p<0.05), before decreasing to previous comparable rates. Compoglass F released relatively more fluoride, and Ariston pHc relatively less, after APF gel application than before. The lowest total amounts over the study were released by Dyract AP and Freedom. The newer compomers, as well as the newer more-viscous GICs, appear to act as fluoride reservoirs to varying extents.