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Conference Paper: A prospective multi-center clinical study of photorejuventation in Asian skin using 2,790 nm infrared laser

TitleA prospective multi-center clinical study of photorejuventation in Asian skin using 2,790 nm infrared laser
Authors
KeywordsMedical sciences
Surgery physics
Optics
Issue Date2009
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073
Citation
The 29th Annual Scientific Conference of the American Society for Laser Medicine and Surgery (ASLMS), National Harbor, MD., 3-5 April 2009. In Lasers in Surgery and Medicine, 2009, v. 41 suppl. 21, p. 42, abstract no. 120 How to Cite?
AbstractBACKGROUND: This was a prospective multi-center clinical study to evaluate the safety and efficacy of the 2,790 nm Er:YSGG laser for resurfacing in Asians. STUDY: Forty Asian subjects with Fitzpatrick skin types III–V, and moderate to severe photodamage were recruited in two clinical centers. Two treatments were performed at 4-week intervals. A 2,790 nm mm laser (Pearl1, Cutera, Brisbane, CA) was used with settings of 2.0 J/cm2 fluence, 0.4 ms pulse width and 20% overlap. The whole face, including eyelids and periorbital areas, was treated with one pass. Standardized photographs were taken with the Canfield VISIA CR system at baseline, and then one and three months after the second treatment. Two blinded assessors evaluated the photographs to assess the degree of improvement in fine lines, skin texture, irregular pigmentation, pigment spots, pore size and telangiectasia on a scale of 0 (no improvement) to 4 (excellent improvement). Patient satisfaction scores were also obtained. Cutometry was performed at five standard anatomical points on each visit. RESULTS: All subjects tolerated the procedure well using topical anesthesia. Mean erythema and desquamation times were 3.2 and 6.2 days respectively. Masked observers’ evaluation documented statistically significant improvement in terms of fine lines, irregular pigmentation, pigment spots and telangiectasia (p<0.05, Wilcoxon signed-rank test). A high level of patients’ satisfaction was achieved, with 90.3% of subjects reporting moderate to excellent overall improvement. Cutometry showed statistically significant improvement in skin elasticity at all points. There was one case of mild postinflammatory hyperpigmentation (1.25%), and one case of herpes simplex infection (1.25%). CONCLUSION: The 2,790 nm Er:YSGG laser appears to be safe and effective for photorejuvenation in Asians with limited downtime and minimal adverse sequelae. It may be complimentary to other laser treatments.
DescriptionThis journal suppl. entitled: Supplement: American Society for Laser Medicine and Surgery Twenty-Ninth Annual Conference April 1–5, 2009
Persistent Identifierhttp://hdl.handle.net/10722/63917
ISSN
2023 Impact Factor: 2.2
2023 SCImago Journal Rankings: 0.810

 

DC FieldValueLanguage
dc.contributor.authorYu, CSen_HK
dc.contributor.authorNegishi, Ken_HK
dc.contributor.authorShek, SYNen_HK
dc.contributor.authorChan, Nen_HK
dc.contributor.authorChan, HHL-
dc.date.accessioned2010-07-13T04:35:38Z-
dc.date.available2010-07-13T04:35:38Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 29th Annual Scientific Conference of the American Society for Laser Medicine and Surgery (ASLMS), National Harbor, MD., 3-5 April 2009. In Lasers in Surgery and Medicine, 2009, v. 41 suppl. 21, p. 42, abstract no. 120-
dc.identifier.issn0196-8092-
dc.identifier.urihttp://hdl.handle.net/10722/63917-
dc.descriptionThis journal suppl. entitled: Supplement: American Society for Laser Medicine and Surgery Twenty-Ninth Annual Conference April 1–5, 2009en_HK
dc.description.abstractBACKGROUND: This was a prospective multi-center clinical study to evaluate the safety and efficacy of the 2,790 nm Er:YSGG laser for resurfacing in Asians. STUDY: Forty Asian subjects with Fitzpatrick skin types III–V, and moderate to severe photodamage were recruited in two clinical centers. Two treatments were performed at 4-week intervals. A 2,790 nm mm laser (Pearl1, Cutera, Brisbane, CA) was used with settings of 2.0 J/cm2 fluence, 0.4 ms pulse width and 20% overlap. The whole face, including eyelids and periorbital areas, was treated with one pass. Standardized photographs were taken with the Canfield VISIA CR system at baseline, and then one and three months after the second treatment. Two blinded assessors evaluated the photographs to assess the degree of improvement in fine lines, skin texture, irregular pigmentation, pigment spots, pore size and telangiectasia on a scale of 0 (no improvement) to 4 (excellent improvement). Patient satisfaction scores were also obtained. Cutometry was performed at five standard anatomical points on each visit. RESULTS: All subjects tolerated the procedure well using topical anesthesia. Mean erythema and desquamation times were 3.2 and 6.2 days respectively. Masked observers’ evaluation documented statistically significant improvement in terms of fine lines, irregular pigmentation, pigment spots and telangiectasia (p<0.05, Wilcoxon signed-rank test). A high level of patients’ satisfaction was achieved, with 90.3% of subjects reporting moderate to excellent overall improvement. Cutometry showed statistically significant improvement in skin elasticity at all points. There was one case of mild postinflammatory hyperpigmentation (1.25%), and one case of herpes simplex infection (1.25%). CONCLUSION: The 2,790 nm Er:YSGG laser appears to be safe and effective for photorejuvenation in Asians with limited downtime and minimal adverse sequelae. It may be complimentary to other laser treatments.-
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073-
dc.relation.ispartofLasers in Surgery and Medicine-
dc.rightsLasers in Surgery and Medicine. Copyright © John Wiley & Sons, Inc.-
dc.subjectMedical sciences-
dc.subjectSurgery physics-
dc.subjectOptics-
dc.titleA prospective multi-center clinical study of photorejuventation in Asian skin using 2,790 nm infrared laseren_HK
dc.typeConference_Paperen_HK
dc.identifier.emailYu, CS: carolsyu@hku.hken_HK
dc.identifier.emailShek, SYN: samantha.shek@gmail.comen_HK
dc.identifier.emailChan, HHL: hhlchan@hkucc.hku.hk-
dc.identifier.authorityYu, CS=rp00305en_HK
dc.identifier.doi10.1002/lsm.20783-
dc.identifier.hkuros164700en_HK
dc.identifier.volume41-
dc.identifier.issuesuppl. 21-
dc.identifier.spage42, abstract no. 120-
dc.identifier.epage42, abstract no. 120-
dc.publisher.placeUnited States-
dc.identifier.issnl0196-8092-

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