Fractional carbon dioxide laser resurfacing for skin rejuvenation, acne scar and facial scar in Asians

Abstract

BACKGROUND: Ablative fractional resurfacing (AFR) is a new modality for photorejuvenation and acne scars which combines carbon dioxide (CO2) laser ablation with fractional photothermolysis. The objective is to evaluate the efficacy and side effects of a new fractional CO2 ablative device (Fraxel Re:pair) for skin rejuvenation, acne scars and facial scars in Asians. STUDY: Each patient underwent one full-face treatment. The energy level ranged from 5–70 mJ (one case with pre-existing melasma was treated with 5 mJ; remaining cases with 10–70 mJ). Treatment levels ranged from 7–13. Improvement in skin texture, laxity, wrinkles, enlarged pores, pigmentation irregularity, and adverse effects were assessed up to 6 months post treatment. Standardized photographs using the Canfield Visia CR system1 were assessed by an independent observer. Subjective improvements were assessed by patient questionnaires. RESULTS: Twelve Chinese patients (skin type III–V, mean age 49) were included. Significant improvements were seen for skin texture (p¼0.020), laxity (p¼0.023), wrinkles (p¼0.026) and enlarged pores (p¼0.024) in the skin rejuvenation group. For the acne and facial scars group, significant improvements were seen for skin laxity (p¼0.046) and scar (p¼0.038). Mild postinflammatory hyperpigmentation and erythema were seen in 58.3% and 41.7% of patients respectively. 87.5% of patients were satisfied with outcome. CONCLUSION: Ablative fractional CO2 resurfacing laser is effective for skin rejuvenation, acne scars and facial scars in Asians. Suitable candidates include elderly males and females with photoaging, as well as males with acne scars.