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Article: Estimation of the serial interval of influenza

TitleEstimation of the serial interval of influenza
Authors
Cowling, BJFang, VJRiley, SMalik Peiris, JSLeung, GM
Issue Date2009
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.epidem.com
Citation
Epidemiology, 2009, v. 20 n. 3, p. 344-347 How to Cite?
DOI: http://dx.doi.org/10.1097/EDE.0b013e31819d1092
AbstractBACKGROUND: Estimates of the clinical-onset serial interval of human influenza infection (time between onset of symptoms in an index case and a secondary case) are used to inform public health policy and to construct mathematical models of influenza transmission. We estimate the serial interval of laboratory-confirmed influenza transmission in households. METHODS: Index cases were recruited after reporting to a primary healthcare center with symptoms. Members of their households were followed-up with repeated home visits. RESULTS: Assuming a Weibull model and accounting for selection bias inherent in our field study design, we used symptom-onset times from 14 pairs of infector/infectee to estimate a mean serial interval of 3.6 days (95% confidence interval = 2.9-4.3 days), with standard deviation 1.6 days. CONCLUSION: The household serial interval of influenza may be longer than previously estimated. Studies of the complete serial interval, based on transmission in all community contexts, are a priority. © 2009 Lippincott Williams & Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/60330
ISSN
1044-3983
2023 Impact Factor: 4.7
2023 SCImago Journal Rankings: 0.655
PubMed Central ID
PMC3057478
ISI Accession Number ID
WOS:000265199800007
Funding AgencyGrant Number
US Centers for Disease Control and Prevention1 U01 C1000439-01
Control of Infectious Disease, Food and Health Bureau, Government of the Hong Kong SARHKU-AA-23
US National Institutes of Health5 U01 GM076497
Hong Kong University Grants CommitteeAoE/M-12/06
Funding Information:

Supported by the US Centers for Disease Control and Prevention (Grant no: 1 U01 C1000439-01), the Research Fund for the Control of Infectious Disease, Food and Health Bureau, Government of the Hong Kong SAR (Grant no: HKU-AA-23), US National Institutes of Health cooperative agreement 5 U01 GM076497 (Models of Infectious Disease Agent Study, ML), and the Area of Excellence Scheme of the Hong Kong University Grants Committee (Grant no: AoE/M-12/06).

References
References in Scopus
Grants
Control of Pandemic and Inter-pandemic Influenza

 

DC FieldValueLanguage
dc.contributor.authorCowling, BJen_HK
dc.contributor.authorFang, VJen_HK
dc.contributor.authorRiley, Sen_HK
dc.contributor.authorMalik Peiris, JSen_HK
dc.contributor.authorLeung, GMen_HK
dc.date.accessioned2010-05-31T04:08:24Z-
dc.date.available2010-05-31T04:08:24Z-
dc.date.issued2009en_HK
dc.identifier.citationEpidemiology, 2009, v. 20 n. 3, p. 344-347en_HK
dc.identifier.issn1044-3983en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60330-
dc.description.abstractBACKGROUND: Estimates of the clinical-onset serial interval of human influenza infection (time between onset of symptoms in an index case and a secondary case) are used to inform public health policy and to construct mathematical models of influenza transmission. We estimate the serial interval of laboratory-confirmed influenza transmission in households. METHODS: Index cases were recruited after reporting to a primary healthcare center with symptoms. Members of their households were followed-up with repeated home visits. RESULTS: Assuming a Weibull model and accounting for selection bias inherent in our field study design, we used symptom-onset times from 14 pairs of infector/infectee to estimate a mean serial interval of 3.6 days (95% confidence interval = 2.9-4.3 days), with standard deviation 1.6 days. CONCLUSION: The household serial interval of influenza may be longer than previously estimated. Studies of the complete serial interval, based on transmission in all community contexts, are a priority. © 2009 Lippincott Williams & Wilkins, Inc.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.epidem.comen_HK
dc.relation.ispartofEpidemiologyen_HK
dc.rightsEpidemiology. Copyright © Lippincott Williams & Wilkins.en_HK
dc.titleEstimation of the serial interval of influenzaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1044-3983&volume=20&issue=3&spage=344&epage=347&date=2009&atitle=Estimation+of+the+serial+interval+of+influenzaen_HK
dc.identifier.emailCowling, BJ: bcowling@hku.hken_HK
dc.identifier.emailRiley, S: steven.riley@hku.hken_HK
dc.identifier.emailMalik Peiris, JS: malik@hkucc.hku.hken_HK
dc.identifier.emailLeung, GM: gmleung@hku.hken_HK
dc.identifier.authorityCowling, BJ=rp01326en_HK
dc.identifier.authorityRiley, S=rp00511en_HK
dc.identifier.authorityMalik Peiris, JS=rp00410en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/EDE.0b013e31819d1092en_HK
dc.identifier.pmid19279492en_HK
dc.identifier.pmcidPMC3057478-
dc.identifier.scopuseid_2-s2.0-67651083503en_HK
dc.identifier.hkuros155221en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67651083503&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume20en_HK
dc.identifier.issue3en_HK
dc.identifier.spage344en_HK
dc.identifier.epage347en_HK
dc.identifier.isiWOS:000265199800007-
dc.publisher.placeUnited Statesen_HK
dc.relation.projectControl of Pandemic and Inter-pandemic Influenza-
dc.identifier.scopusauthoridCowling, BJ=8644765500en_HK
dc.identifier.scopusauthoridFang, VJ=24474130400en_HK
dc.identifier.scopusauthoridRiley, S=7102619416en_HK
dc.identifier.scopusauthoridMalik Peiris, JS=7005486823en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.issnl1044-3983-

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