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Article: Smoking, smoking cessation and aortic arch calcification in older Chinese: The Guangzhou Biobank Cohort Study

TitleSmoking, smoking cessation and aortic arch calcification in older Chinese: The Guangzhou Biobank Cohort Study
Authors
KeywordsAortic arch calcification
Chinese
Smoking
Smoking cessation
Issue Date2009
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosis
Citation
Atherosclerosis, 2009, v. 202 n. 2, p. 529-534 How to Cite?
AbstractObjective: To study the association between smoking, smoking cessation and aortic arc calcification (AAC) in an older Chinese population. Methods: A total of 3022 men and 7279 women aged 50-85 years were recruited and received a medical check-up including measurement of fasting plasma vascular risk factors. Two radiologists reviewed the posterior-anterior plain chest X-ray radiographs and assessed AAC together. Information on smoking status, socioeconomic and lifestyle factors was collected. Results: The crude prevalence of AAC in men (38.58%) was lower than that in women (41.37%). The adjusted odds ratios of AAC increased significantly across never, ex- and current smokers in both genders. Dose-response relationships were observed among current smokers for smoking amount (cigarettes/day), smoking duration (years) and cigarette pack-years in both genders (all p < 0.01). The odds ratios decreased significantly (p = 0.018) with longer duration of quitting in light ex-smoking men (<23.5 pack-years) but showed no beneficial effect (p = 0.72) for heavy ex-smokers (≥23.5 pack-years). Conclusion: Smoking increased the risk of AAC in Chinese, while smoking cessation decreased the risk only in male light ex-smokers. Chest X-ray is a cheap and simple method to detect AAC, which should be an important warning signal for immediate smoking cessation. © 2008 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/60305
ISSN
2023 Impact Factor: 4.9
2023 SCImago Journal Rankings: 1.461
ISI Accession Number ID
Funding AgencyGrant Number
The University of Hong Kong Foundation for Educational Development and Research, Hong Kong
the Guangzhou Public Health Bureau
Guangzhou Science and Technology Bureau, Guangzhou, China
The University of Birmingham, UK
Funding Information:

The study is funded by The University of Hong Kong Foundation for Educational Development and Research, Hong Kong; the Guangzhou Public Health Bureau and the Guangzhou Science and Technology Bureau, Guangzhou, China; and The University of Birmingham, UK. We thank Professor Zhang C.H. and Dr. Jiao S.H. for reviewing the chest radiographs. The Guangzhou Biobank Cohort Study investigators include: the Guangzhou No. 12 Hospital: X.Q. Lao, W.S. Zhang, M. Cao, T. Zhu, B. Liu, C.Q. Jiang (CoPI); The University of Hong Kong: G.N. Thomas, C.M. Schooling, S.M. McGhee, R. Fielding, G.M. Leung, T.H. Lam (Co-PI); The University of Birmingham: P. Adab, M. Zeegers, K.K. Cheng (Co-PI).

References

 

DC FieldValueLanguage
dc.contributor.authorJiang, CQen_HK
dc.contributor.authorLao, XQen_HK
dc.contributor.authorYin, Pen_HK
dc.contributor.authorThomas, GNen_HK
dc.contributor.authorZhang, WSen_HK
dc.contributor.authorLiu, Ben_HK
dc.contributor.authorAdab, Pen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorCheng, KKen_HK
dc.date.accessioned2010-05-31T04:07:56Z-
dc.date.available2010-05-31T04:07:56Z-
dc.date.issued2009en_HK
dc.identifier.citationAtherosclerosis, 2009, v. 202 n. 2, p. 529-534en_HK
dc.identifier.issn0021-9150en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60305-
dc.description.abstractObjective: To study the association between smoking, smoking cessation and aortic arc calcification (AAC) in an older Chinese population. Methods: A total of 3022 men and 7279 women aged 50-85 years were recruited and received a medical check-up including measurement of fasting plasma vascular risk factors. Two radiologists reviewed the posterior-anterior plain chest X-ray radiographs and assessed AAC together. Information on smoking status, socioeconomic and lifestyle factors was collected. Results: The crude prevalence of AAC in men (38.58%) was lower than that in women (41.37%). The adjusted odds ratios of AAC increased significantly across never, ex- and current smokers in both genders. Dose-response relationships were observed among current smokers for smoking amount (cigarettes/day), smoking duration (years) and cigarette pack-years in both genders (all p < 0.01). The odds ratios decreased significantly (p = 0.018) with longer duration of quitting in light ex-smoking men (<23.5 pack-years) but showed no beneficial effect (p = 0.72) for heavy ex-smokers (≥23.5 pack-years). Conclusion: Smoking increased the risk of AAC in Chinese, while smoking cessation decreased the risk only in male light ex-smokers. Chest X-ray is a cheap and simple method to detect AAC, which should be an important warning signal for immediate smoking cessation. © 2008 Elsevier Ireland Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosisen_HK
dc.relation.ispartofAtherosclerosisen_HK
dc.rightsAtherosclerosis. Copyright © Elsevier Ireland Ltd.en_HK
dc.subjectAortic arch calcification-
dc.subjectChinese-
dc.subjectSmoking-
dc.subjectSmoking cessation-
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshAgingen_HK
dc.subject.meshAorta, Thoracic - pathologyen_HK
dc.subject.meshAortic Diseases - ethnology - pathologyen_HK
dc.subject.meshAsian Continental Ancestry Group - statistics & numerical dataen_HK
dc.subject.meshCalcinosis - ethnology - pathologyen_HK
dc.subject.meshCohort Studiesen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPrevalenceen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshSmoking - ethnologyen_HK
dc.subject.meshSmoking Cessation - statistics & numerical dataen_HK
dc.titleSmoking, smoking cessation and aortic arch calcification in older Chinese: The Guangzhou Biobank Cohort Studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9150&volume=202&issue=2&spage=529&epage=534&date=2009&atitle=Smoking,+smoking+cessation+and+aortic+arch+calcification+in+older+Chinese:+the+Guangzhou+Biobank+Cohort+Studyen_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.atherosclerosis.2008.03.004en_HK
dc.identifier.pmid18436226-
dc.identifier.scopuseid_2-s2.0-58549118061en_HK
dc.identifier.hkuros154418en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58549118061&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume202en_HK
dc.identifier.issue2en_HK
dc.identifier.spage529en_HK
dc.identifier.epage534en_HK
dc.identifier.isiWOS:000263427300027-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridJiang, CQ=10639500500en_HK
dc.identifier.scopusauthoridLao, XQ=14031637000en_HK
dc.identifier.scopusauthoridYin, P=14623527300en_HK
dc.identifier.scopusauthoridThomas, GN=35465269900en_HK
dc.identifier.scopusauthoridZhang, WS=13410704100en_HK
dc.identifier.scopusauthoridLiu, B=36079151900en_HK
dc.identifier.scopusauthoridAdab, P=6601949045en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridCheng, KK=7402997800en_HK
dc.identifier.issnl0021-9150-

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