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Article: Use of oral valaciclovir in a 12-year-old boy with herpes simplex encephalitis

TitleUse of oral valaciclovir in a 12-year-old boy with herpes simplex encephalitis
Authors
Chan, PKSChow, PCPeiris, JSMMak, AWCHuen, KF
KeywordsAcyclovir/analogs and derivatives
Encephalitis, herpes simplex/drug therapy
Treatment outcome
Issue Date2000
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
Citation
Hong Kong Medical Journal, 2000, v. 6 n. 1, p. 119-121 How to Cite?
AbstractWe report on a 12-year-old boy with herpes simplex encephalitis, in whom a severe localised skin reaction developed following the infusion of intravenous acyclovir. Oral valaciclovir was given as continuation therapy to complete the 3-week course of antiviral treatment and resulted in complete recovery without side effects. This report illustrates the advantage of using the polymerase chain reaction to diagnose herpes simplex encephalitis and the potential use of newer antiviral agents, such as valaciclovir, as continuation therapy in the management of the infection. The higher oral bioavailability of newer antiviral agents allows part of the extended treatment period of patients with herpes simplex encephalitis to be carried out as an ambulatory oral regimen.
Persistent Identifierhttp://hdl.handle.net/10722/53433
ISSN
1024-2708
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 0.261

 

DC FieldValueLanguage
dc.contributor.authorChan, PKSen_HK
dc.contributor.authorChow, PCen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorMak, AWCen_HK
dc.contributor.authorHuen, KFen_HK
dc.date.accessioned2009-04-03T07:19:38Z-
dc.date.available2009-04-03T07:19:38Z-
dc.date.issued2000en_HK
dc.identifier.citationHong Kong Medical Journal, 2000, v. 6 n. 1, p. 119-121en_HK
dc.identifier.issn1024-2708en_HK
dc.identifier.urihttp://hdl.handle.net/10722/53433-
dc.description.abstractWe report on a 12-year-old boy with herpes simplex encephalitis, in whom a severe localised skin reaction developed following the infusion of intravenous acyclovir. Oral valaciclovir was given as continuation therapy to complete the 3-week course of antiviral treatment and resulted in complete recovery without side effects. This report illustrates the advantage of using the polymerase chain reaction to diagnose herpes simplex encephalitis and the potential use of newer antiviral agents, such as valaciclovir, as continuation therapy in the management of the infection. The higher oral bioavailability of newer antiviral agents allows part of the extended treatment period of patients with herpes simplex encephalitis to be carried out as an ambulatory oral regimen.en_HK
dc.languageengen_HK
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.htmlen_HK
dc.relation.ispartofHong Kong Medical Journalen_HK
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Medical Association.en_HK
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAcyclovir/analogs and derivativesen_HK
dc.subjectEncephalitis, herpes simplex/drug therapyen_HK
dc.subjectTreatment outcomeen_HK
dc.subject.meshAcyclovir - analogs & derivatives - therapeutic useen_HK
dc.subject.meshAntiviral Agents - therapeutic useen_HK
dc.subject.meshEncephalitis, Herpes Simplex - diagnosis - drug therapyen_HK
dc.subject.meshValine - analogs & derivatives - therapeutic useen_HK
dc.subject.meshPolymerase Chain Reactionen_HK
dc.titleUse of oral valaciclovir in a 12-year-old boy with herpes simplex encephalitisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1024-2708&volume=6&issue=1&spage=119&epage=121&date=2000&atitle=Use+of+oral+valaciclovir+in+a+12-year-old+boy+with+herpes+simplex+encephalitisen_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid10793414-
dc.identifier.scopuseid_2-s2.0-0034035111en_HK
dc.identifier.hkuros54165-
dc.identifier.volume6en_HK
dc.identifier.issue1en_HK
dc.identifier.spage119en_HK
dc.identifier.epage121en_HK
dc.publisher.placeHong Kongen_HK
dc.identifier.scopusauthoridChan, PKS=7403497792en_HK
dc.identifier.scopusauthoridChow, PC=36917522500en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.scopusauthoridMak, AWC=23568058900en_HK
dc.identifier.scopusauthoridHuen, KF=36942478900en_HK
dc.identifier.issnl1024-2708-

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