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Article: Prevalence and predictors of default from tuberculosis treatment in Hong Kong

TitlePrevalence and predictors of default from tuberculosis treatment in Hong Kong
香港肺結核患者延誤就醫的比率以及具預測性的因素
Authors
KeywordsHong Kong
Treatment refusal
Tuberculosis
Issue Date2003
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org.hk
Citation
Hong Kong Medical Journal, 2003, v. 9 n. 4, p. 263-268 How to Cite?
AbstractOBJECTIVE: To determine the prevalence and risk factors of default from tuberculosis treatment in Hong Kong. DESIGN: Retrospective study. SETTING: Data were obtained from programme forms completed by physicians in the Hong Kong Government Tuberculosis and Chest Service and from medical records from Hong Kong chest clinics. PATIENTS: In all, 5917 patients registered for antituberculous drug therapy in 1996; medical records of 5757 patients were reviewed. MAIN OUTCOME MEASURES: Patients who defaulted treatment were defined as those who had failed to collect medication for more than 2 consecutive months after the date of the last attendance during the course of treatment. Demographic and clinical characteristics, including history, treatment, and outcome, were compared between defaulters and non-defaulters, both among the whole group and among those with pulmonary disease. RESULTS: There were 442 (8%) patients who defaulted from treatment. Forty-five percent of those who defaulted did so in the first 2 months of treatment. Key risk factors associated with non-compliance were a history of default, male sex, and a history of concomitant liver disease or lung cancer. Among patients with pulmonary tuberculosis (381 defaulters and 1537 non-defaulters), multiple drug resistance was also associated with default from treatment. Among defaulters with pulmonary disease, 39% were still bacteriologically positive at the time of default. CONCLUSION: Default from treatment may be partially responsible for the persistent high rates of tuberculosis in Hong Kong in the past decade. Health professionals should ensure that all barriers to treatment be removed and that incentives be used to encourage treatment compliance.
Persistent Identifierhttp://hdl.handle.net/10722/45132
ISSN
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 0.261

 

DC FieldValueLanguage
dc.contributor.authorChan-Yeung, MMWen_HK
dc.contributor.authorNoertjojo, Ken_HK
dc.contributor.authorLeung, CCen_HK
dc.contributor.authorChan, SLen_HK
dc.contributor.authorTam, CMen_HK
dc.date.accessioned2007-10-30T06:18:03Z-
dc.date.available2007-10-30T06:18:03Z-
dc.date.issued2003en_HK
dc.identifier.citationHong Kong Medical Journal, 2003, v. 9 n. 4, p. 263-268en_HK
dc.identifier.issn1024-2708en_HK
dc.identifier.urihttp://hdl.handle.net/10722/45132-
dc.description.abstractOBJECTIVE: To determine the prevalence and risk factors of default from tuberculosis treatment in Hong Kong. DESIGN: Retrospective study. SETTING: Data were obtained from programme forms completed by physicians in the Hong Kong Government Tuberculosis and Chest Service and from medical records from Hong Kong chest clinics. PATIENTS: In all, 5917 patients registered for antituberculous drug therapy in 1996; medical records of 5757 patients were reviewed. MAIN OUTCOME MEASURES: Patients who defaulted treatment were defined as those who had failed to collect medication for more than 2 consecutive months after the date of the last attendance during the course of treatment. Demographic and clinical characteristics, including history, treatment, and outcome, were compared between defaulters and non-defaulters, both among the whole group and among those with pulmonary disease. RESULTS: There were 442 (8%) patients who defaulted from treatment. Forty-five percent of those who defaulted did so in the first 2 months of treatment. Key risk factors associated with non-compliance were a history of default, male sex, and a history of concomitant liver disease or lung cancer. Among patients with pulmonary tuberculosis (381 defaulters and 1537 non-defaulters), multiple drug resistance was also associated with default from treatment. Among defaulters with pulmonary disease, 39% were still bacteriologically positive at the time of default. CONCLUSION: Default from treatment may be partially responsible for the persistent high rates of tuberculosis in Hong Kong in the past decade. Health professionals should ensure that all barriers to treatment be removed and that incentives be used to encourage treatment compliance.en_HK
dc.format.extent339300 bytes-
dc.format.extent5292 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org.hken_HK
dc.subjectHong Kong-
dc.subjectTreatment refusal-
dc.subjectTuberculosis-
dc.subject.meshAntitubercular Agents - therapeutic useen_HK
dc.subject.meshTuberculosis, Pulmonary - drug therapy - epidemiologyen_HK
dc.subject.meshLiver Diseases - epidemiologyen_HK
dc.subject.meshPatient Dropouts - statistics & numerical dataen_HK
dc.subject.meshTuberculosis, Multidrug-Resistant - epidemiologyen_HK
dc.titlePrevalence and predictors of default from tuberculosis treatment in Hong Kongen_HK
dc.title香港肺結核患者延誤就醫的比率以及具預測性的因素zh_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1024-2708&volume=9&issue=4&spage=263&epage=268&date=2003&atitle=Prevalence+and+predictors+of+default+from+tuberculosis+treatment+in+Hong+Kongen_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid12904614-
dc.identifier.scopuseid_2-s2.0-0041662148-
dc.identifier.hkuros81380-
dc.identifier.issnl1024-2708-

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