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- Publisher Website: 10.1016/0888-7543(89)90128-6
- Scopus: eid_2-s2.0-0024763772
- PMID: 2591968
- WOS: WOS:A1989AZ32800023
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Article: Twenty-five loci form a continuous linkage map of markers for human chromosome 7
Title | Twenty-five loci form a continuous linkage map of markers for human chromosome 7 |
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Authors | |
Issue Date | 1989 |
Publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygeno |
Citation | Genomics, 1989, v. 5 n. 4, p. 866-873 How to Cite? |
Abstract | We have constructed a primary genetic linkage map from DNA markers that define 25 loci on chromosome 7. The markers form a continuous linkage group of 141 cM in males and 340 cM in females; female genetic distances were on average more than twofold higher than those in males throughout the chromosome. The average heterozygosity of the loci was 45%. A subset of the markers can be used for efficient application of this map to studies of human genetic disease. © 1989. |
Persistent Identifier | http://hdl.handle.net/10722/44233 |
ISSN | 2023 Impact Factor: 3.4 2023 SCImago Journal Rankings: 0.850 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lathrop, GM | en_HK |
dc.contributor.author | O'Connell, P | en_HK |
dc.contributor.author | Leppert, M | en_HK |
dc.contributor.author | Nakamura, Y | en_HK |
dc.contributor.author | Farrall, M | en_HK |
dc.contributor.author | Tsui, LC | en_HK |
dc.contributor.author | Lalouel, JM | en_HK |
dc.contributor.author | White, R | en_HK |
dc.date.accessioned | 2007-09-12T03:49:32Z | - |
dc.date.available | 2007-09-12T03:49:32Z | - |
dc.date.issued | 1989 | en_HK |
dc.identifier.citation | Genomics, 1989, v. 5 n. 4, p. 866-873 | en_HK |
dc.identifier.issn | 0888-7543 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/44233 | - |
dc.description.abstract | We have constructed a primary genetic linkage map from DNA markers that define 25 loci on chromosome 7. The markers form a continuous linkage group of 141 cM in males and 340 cM in females; female genetic distances were on average more than twofold higher than those in males throughout the chromosome. The average heterozygosity of the loci was 45%. A subset of the markers can be used for efficient application of this map to studies of human genetic disease. © 1989. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygeno | en_HK |
dc.relation.ispartof | Genomics | en_HK |
dc.subject.mesh | Alleles | en_HK |
dc.subject.mesh | Chromosome mapping | en_HK |
dc.subject.mesh | Chromosomes, human, pair 7 | en_HK |
dc.subject.mesh | Crossing over, genetic | en_HK |
dc.subject.mesh | Genetic markers | en_HK |
dc.title | Twenty-five loci form a continuous linkage map of markers for human chromosome 7 | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Tsui, LC: tsuilc@hkucc.hku.hk | en_HK |
dc.identifier.authority | Tsui, LC=rp00058 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_HK |
dc.identifier.doi | 10.1016/0888-7543(89)90128-6 | en_HK |
dc.identifier.pmid | 2591968 | - |
dc.identifier.scopus | eid_2-s2.0-0024763772 | en_HK |
dc.identifier.volume | 5 | en_HK |
dc.identifier.issue | 4 | en_HK |
dc.identifier.spage | 866 | en_HK |
dc.identifier.epage | 873 | en_HK |
dc.identifier.isi | WOS:A1989AZ32800023 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Lathrop, GM=7102890692 | en_HK |
dc.identifier.scopusauthorid | O'Connell, P=7202733781 | en_HK |
dc.identifier.scopusauthorid | Leppert, M=35351313000 | en_HK |
dc.identifier.scopusauthorid | Nakamura, Y=36013862000 | en_HK |
dc.identifier.scopusauthorid | Farrall, M=7006468255 | en_HK |
dc.identifier.scopusauthorid | Tsui, LC=7102754167 | en_HK |
dc.identifier.scopusauthorid | Lalouel, JM=7102287621 | en_HK |
dc.identifier.scopusauthorid | White, R=7501421957 | en_HK |
dc.identifier.issnl | 0888-7543 | - |