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Article: Craniofacial profile in Asian and white subjects with obstructive sleep apnoea

TitleCraniofacial profile in Asian and white subjects with obstructive sleep apnoea
Authors
Issue Date2005
PublisherB M J Publishing Group. The Journal's web site is located at http://thorax.bmjjournals.com/
Citation
Thorax, 2005, v. 60 n. 6, p. 504-510 How to Cite?
AbstractBackground: Clinical detection of structural narrowing of the upper airway may facilitate early recognition of obstructive sleep apnoea (OSA). To determine whether the craniofacial profile predicts the presence of OSA, the upper airway and craniofacial structure of 239 consecutive patients (164 Asian and 75 white subjects) referred to two sleep centres (Hong Kong and Vancouver) were prospectively examined for suspected sleep disordered breathing. Methods: All subjects underwent a history and physical examination with measurements of anthropometric parameters and craniofacial structure including neck circumference, thyromental distance, thyromental angle, and Mallampati oropharyngeal score. OSA was defined as an apnoea-hypopnoea index (AHI) of ≥5/hour on full overnight polysomnography. Results: Discriminant function analysis indicated that the Mallampati score (F = 0.70), thyromental angle (F = 0.60), neck circumference (F = 0.54), body mass index (F = 0.53), and age (F = 0.53) were the best predictors of OSA. After controlling for ethnicity, body mass index and neck circumference, patients with OSA were older, had larger thyromental angles, and higher Mallampati scores than non-apnoeic subjects. These variables remained significantly different between OSA patients and controls across a range of cut-off values of AHI from 5 to 30/hour. Conclusions: A crowded posterior oropharynx and a steep thyromental plane predict OSA across two different ethnic groups and varying degrees of obesity.
Persistent Identifierhttp://hdl.handle.net/10722/42159
ISSN
2023 Impact Factor: 9.0
2023 SCImago Journal Rankings: 3.001
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, Ben_HK
dc.contributor.authorIp, MSMen_HK
dc.contributor.authorTench, Een_HK
dc.contributor.authorRyan, CFen_HK
dc.date.accessioned2007-01-08T02:30:30Z-
dc.date.available2007-01-08T02:30:30Z-
dc.date.issued2005en_HK
dc.identifier.citationThorax, 2005, v. 60 n. 6, p. 504-510en_HK
dc.identifier.issn0040-6376en_HK
dc.identifier.urihttp://hdl.handle.net/10722/42159-
dc.description.abstractBackground: Clinical detection of structural narrowing of the upper airway may facilitate early recognition of obstructive sleep apnoea (OSA). To determine whether the craniofacial profile predicts the presence of OSA, the upper airway and craniofacial structure of 239 consecutive patients (164 Asian and 75 white subjects) referred to two sleep centres (Hong Kong and Vancouver) were prospectively examined for suspected sleep disordered breathing. Methods: All subjects underwent a history and physical examination with measurements of anthropometric parameters and craniofacial structure including neck circumference, thyromental distance, thyromental angle, and Mallampati oropharyngeal score. OSA was defined as an apnoea-hypopnoea index (AHI) of ≥5/hour on full overnight polysomnography. Results: Discriminant function analysis indicated that the Mallampati score (F = 0.70), thyromental angle (F = 0.60), neck circumference (F = 0.54), body mass index (F = 0.53), and age (F = 0.53) were the best predictors of OSA. After controlling for ethnicity, body mass index and neck circumference, patients with OSA were older, had larger thyromental angles, and higher Mallampati scores than non-apnoeic subjects. These variables remained significantly different between OSA patients and controls across a range of cut-off values of AHI from 5 to 30/hour. Conclusions: A crowded posterior oropharynx and a steep thyromental plane predict OSA across two different ethnic groups and varying degrees of obesity.en_HK
dc.format.extent179092 bytes-
dc.format.extent98763 bytes-
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dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://thorax.bmjjournals.com/en_HK
dc.relation.ispartofThoraxen_HK
dc.rightsThorax. Copyright © B M J Publishing Group.en_HK
dc.subject.meshAsian continental ancestry group - ethnologyen_HK
dc.subject.meshEuropean continental ancestry group - ethnologyen_HK
dc.subject.meshFace - pathologyen_HK
dc.subject.meshSkull - pathologyen_HK
dc.subject.meshSleep apnea, obstructive - ethnology - pathologyen_HK
dc.titleCraniofacial profile in Asian and white subjects with obstructive sleep apnoeaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0040-6376&volume=60&issue=6&spage=504&epage=510&date=2005&atitle=Craniofacial+profile+in+Asian+and+white+subjects+with+obstructive+sleep+apnoeaen_HK
dc.identifier.emailIp, MSM:msmip@hku.hken_HK
dc.identifier.authorityIp, MSM=rp00347en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1136/thx.2004.031591en_HK
dc.identifier.pmid15923252-
dc.identifier.pmcidPMC1747424-
dc.identifier.scopuseid_2-s2.0-20444468577en_HK
dc.identifier.hkuros98334-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-20444468577&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume60en_HK
dc.identifier.issue6en_HK
dc.identifier.spage504en_HK
dc.identifier.epage510en_HK
dc.identifier.isiWOS:000229433900013-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLam, B=9246012800en_HK
dc.identifier.scopusauthoridIp, MSM=7102423259en_HK
dc.identifier.scopusauthoridTench, E=6506687260en_HK
dc.identifier.scopusauthoridRyan, CF=35556191600en_HK
dc.identifier.issnl0040-6376-

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