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Browsing "Medicine: Journal/Magazine Articles" by Author tomaselli, gf
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Showing results 1 to 16 of 16
Title
Author(s)
Issue Date
Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model
Journal:
Circulation
Tse, HF
Xue, T
Lau, CP
Siu, CW
Wang, K
Zhang, QY
Tomaselli, GF
Akar, FG
Li, RA
2006
Charge conversion enables quantification of the proximity between a normally-neutral μ-conotoxin (GIIIA) site and the Na+ channel pore
Journal:
FEBS Letters
Li, RA
Sato, K
Kodama, K
Kohno, T
Xue, T
Tomaselli, GF
Marbán, E
2002
Charged residues between the selectivity filter and S6 segments contribute to the permeation phenotype of the sodium channel
Journal:
Journal of General Physiology
Li, RA
Vélez, P
Chiamvimonvat, N
Tomaselli, GF
Marbán, E
2000
Clockwise Domain Arrangement of the Sodium Channel Revealed by μ-Conotoxin (GIIIA) Docking Orientation
Journal:
Journal of Biological Chemistry
Li, RA
Ennis, IL
French, RJ
Dudley Jr, SC
Tomaselli, GF
Marbán, E
2001
A conserved ring of charge in mammalian Na + channels: A molecular regulator of the outer pore conformation during slow inactivation
Journal:
Journal of Physiology
Xiong, W
Farukhi, YZ
Tian, Y
Disilvestre, D
Li, RA
Tomaselli, GF
2006
Dependence of μ-conotoxin block of sodium channels on ionic strength but not on the permeating [Na+]. Implications for the distinctive mechanistic interactions between Na+ and K+ channel pore-blocking toxins and their molecular targets
Journal:
Journal of Biological Chemistry
Li, RA
Hui, K
French, RJ
Sato, K
Henrikson, CA
Tomaselli, GF
Marbán, E
2003
Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell-based pacemakers
Journal:
Circulation
Xue, T
Cho, HC
Akar, FG
Tsang, SY
Jones, SP
Marbán, E
Tomaselli, GF
Li, RA
2005
Latent specificity of molecular recognition in sodium channels engineered to discriminate between two "indistinguishable" μ-Conotoxins
Journal:
Biochemistry
Li, RA
Ennis, IL
Tomaselli, GF
French, RJ
Marbán, E
2001
Molecular architecture of the voltage-dependent Na channel: Functional evidence for α helices in the pore
Journal:
Journal of General Physiology
Yamagishi, T
Li, RA
Hsu, K
Marbán, E
Tomaselli, GF
2001
Molecular basis of isoform-specific μ-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels
Journal:
Journal of Biological Chemistry
Li, RA
Ennis, IL
Xue, T
Nguyen, HM
Tomaselli, GF
Goldin, AL
Marbán, E
2003
Molecular motions of the outer ring of charge of the sodium channel: Do they couple to slow inactivation?
Journal:
Journal of General Physiology
Xiong, W
Li, RA
Tian, Y
Tomaselli, GF
2003
A multifunctional aromatic residue in the external pore vestibule of Na+ channels contributes to the local anesthetic receptor
Journal:
Molecular Pharmacology
Suk, YT
Tsushima, RG
Tomaselli, GF
Li, RA
Backx, PH
2005
Non-equilibrium behavior of HCN channels: Insights into the role of HCN channels in native and engineered pacemakers
Journal:
Cardiovascular Research
Azene, EM
Xue, T
Marbán, E
Tomaselli, GF
Li, RA
2005
Novel structural determinants of μ-conotoxin (GIIIB) block in rat skeletal muscle (μ1) Na+ channels
Journal:
Journal of Biological Chemistry
Li, RA
Ennis, IL
Vélez, P
Tomaselli, GF
Marbán, E
2000
Structural basis of differences in isoform-specific gating and lidocaine block between cardiac and skeletal muscle sodium channels
Journal:
Molecular Pharmacology
Li, RA
Ennis, IL
Tomaselli, GF
Marbán, E
2002
Using the deadly μ-conotoxins as probes of voltage-gated sodium channels
Journal:
Toxicon
Li, RA
Tomaselli, GF
2004