File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1203/pdr.0b013e3180457635
- Scopus: eid_2-s2.0-34247469843
- PMID: 17413844
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Epigenetic regulation of neural gene expression and neuronal function
| Title | Epigenetic regulation of neural gene expression and neuronal function |
|---|---|
| Authors | |
| Issue Date | 2007 |
| Citation | Pediatric Research, 2007, v. 61, n. 5 PART 2 SUPPL. How to Cite? |
| Abstract | The development and function of the CNS requires accurate gene transcription control in response to proper environmental signals. Epigenetic mechanisms, including DNA methylation, histone modifications, and other chromatin-remodeling events, are critically important in mediating precise neural gene regulation. This review focuses on discussing the role of DNA methylation and histone modifications in neural lineage differentiation, synaptic plasticity and neural behavior. We postulate that DNA methylation- and histone modification-mediated gene regulation is not only important for neural cell differentiation but also crucial for high-order cognitive functions such as learning and memory. © International Pediatrics Research Foundation, Inc. 2007. All Rights Reserved. |
| Persistent Identifier | http://hdl.handle.net/10722/365673 |
| ISSN | 2023 Impact Factor: 3.1 2023 SCImago Journal Rankings: 1.184 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Feng, Jian | - |
| dc.contributor.author | Fouse, Shaun | - |
| dc.contributor.author | Fan, Guoping | - |
| dc.date.accessioned | 2025-11-05T09:46:46Z | - |
| dc.date.available | 2025-11-05T09:46:46Z | - |
| dc.date.issued | 2007 | - |
| dc.identifier.citation | Pediatric Research, 2007, v. 61, n. 5 PART 2 SUPPL. | - |
| dc.identifier.issn | 0031-3998 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/365673 | - |
| dc.description.abstract | The development and function of the CNS requires accurate gene transcription control in response to proper environmental signals. Epigenetic mechanisms, including DNA methylation, histone modifications, and other chromatin-remodeling events, are critically important in mediating precise neural gene regulation. This review focuses on discussing the role of DNA methylation and histone modifications in neural lineage differentiation, synaptic plasticity and neural behavior. We postulate that DNA methylation- and histone modification-mediated gene regulation is not only important for neural cell differentiation but also crucial for high-order cognitive functions such as learning and memory. © International Pediatrics Research Foundation, Inc. 2007. All Rights Reserved. | - |
| dc.language | eng | - |
| dc.relation.ispartof | Pediatric Research | - |
| dc.title | Epigenetic regulation of neural gene expression and neuronal function | - |
| dc.type | Article | - |
| dc.description.nature | link_to_subscribed_fulltext | - |
| dc.identifier.doi | 10.1203/pdr.0b013e3180457635 | - |
| dc.identifier.pmid | 17413844 | - |
| dc.identifier.scopus | eid_2-s2.0-34247469843 | - |
| dc.identifier.volume | 61 | - |
| dc.identifier.issue | 5 PART 2 SUPPL. | - |