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Book Chapter: Nonenzymatic Oxidized Polyunsaturated Fatty Acid Products in Human Plasma and Urine Samples by LC-QTOF-MS/MS

TitleNonenzymatic Oxidized Polyunsaturated Fatty Acid Products in Human Plasma and Urine Samples by LC-QTOF-MS/MS
Authors
Issue Date2-Oct-2024
PublisherSpringer Nature
Abstract

Oxidative stress induces autooxidation of polyunsaturated fatty acids, producing numerous isoprostanoids and isofuranoids. These oxidized products are measurable in human plasma and urine and serve as oxidative stress biomarkers for chronic diseases. This chapter details the preparation and measurement of α-linolenic acid-derived phytoprostanes and phytofurans in human samples using liquid chromatography–quadrupole time-of-flight tandem mass spectrometry (LC-QToF-MS/MS).


Persistent Identifierhttp://hdl.handle.net/10722/359227
ISBN
ISSN
2023 SCImago Journal Rankings: 0.399

 

DC FieldValueLanguage
dc.contributor.authorLeung, Kin Sum-
dc.contributor.authorLee, Jetty Chung-Yung-
dc.date.accessioned2025-08-26T00:30:16Z-
dc.date.available2025-08-26T00:30:16Z-
dc.date.issued2024-10-02-
dc.identifier.isbn9781071641156-
dc.identifier.issn1064-3745-
dc.identifier.urihttp://hdl.handle.net/10722/359227-
dc.description.abstract<p>Oxidative stress induces autooxidation of polyunsaturated fatty acids, producing numerous isoprostanoids and isofuranoids. These oxidized products are measurable in human plasma and urine and serve as oxidative stress biomarkers for chronic diseases. This chapter details the preparation and measurement of α-linolenic acid-derived phytoprostanes and phytofurans in human samples using liquid chromatography–quadrupole time-of-flight tandem mass spectrometry (LC-QToF-MS/MS).<br></p>-
dc.languageeng-
dc.publisherSpringer Nature-
dc.relation.ispartofMethods in molecular biology-
dc.titleNonenzymatic Oxidized Polyunsaturated Fatty Acid Products in Human Plasma and Urine Samples by LC-QTOF-MS/MS-
dc.typeBook_Chapter-
dc.identifier.doi10.1007/978-1-0716-4116-3_11-
dc.identifier.eissn1940-6029-
dc.identifier.eisbn9781071641163-
dc.identifier.issnl1064-3745-

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