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Article: Detection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024

TitleDetection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024
Authors
Sun, WanyingChoy, Ka TimCheng, Ka ManBrackman, Christopher J.Cheng, Samuel M.S.Sit, Thomas H.C.Tse, Anne C.N.Sims, Leslie D.Gu, HaogaoTang, Amy W.Y.Wong, Andrew N.C.Tsang, Andrew T.L.Koo, Joe C.T.Luk, Leo L.H.Yen, Hui LingPeris, MalikPoon, Leo L.M.
Issue Date9-Jan-2025
PublisherEuropean Centre for Disease Prevention and Control
Citation
Eurosurveillance: Europe's journal on infectious disease surveillance, epidemiology, prevention and control, 2025, v. 30, n. 1 How to Cite?
DOI: http://dx.doi.org/10.2807/1560-7917.ES.2025.30.1.2400839
AbstractWe isolated three genotypes of highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b from wild birds infected with H5N1 (n=12) and H5N8 (n=1) in Hong Kong SAR, 2021–2024. Viruses from two spoonbills from late 2022 were genetically related to a virus from a human in China. Four tested viruses exhibited variable virulence in mice but were susceptible to approved antivirals. No neutralising antibody was detected in 63 age-stratified human sera, suggesting potential risk should the virus adapt to humans.
Persistent Identifierhttp://hdl.handle.net/10722/356810
ISSN
1560-7917
2023 Impact Factor: 9.9
2023 SCImago Journal Rankings: 2.881
ISI Accession Number ID
WOS:001398303700001

 

DC FieldValueLanguage
dc.contributor.authorSun, Wanying-
dc.contributor.authorChoy, Ka Tim-
dc.contributor.authorCheng, Ka Man-
dc.contributor.authorBrackman, Christopher J.-
dc.contributor.authorCheng, Samuel M.S.-
dc.contributor.authorSit, Thomas H.C.-
dc.contributor.authorTse, Anne C.N.-
dc.contributor.authorSims, Leslie D.-
dc.contributor.authorGu, Haogao-
dc.contributor.authorTang, Amy W.Y.-
dc.contributor.authorWong, Andrew N.C.-
dc.contributor.authorTsang, Andrew T.L.-
dc.contributor.authorKoo, Joe C.T.-
dc.contributor.authorLuk, Leo L.H.-
dc.contributor.authorYen, Hui Ling-
dc.contributor.authorPeris, Malik-
dc.contributor.authorPoon, Leo L.M.-
dc.date.accessioned2025-06-19T00:35:11Z-
dc.date.available2025-06-19T00:35:11Z-
dc.date.issued2025-01-09-
dc.identifier.citationEurosurveillance: Europe's journal on infectious disease surveillance, epidemiology, prevention and control, 2025, v. 30, n. 1-
dc.identifier.issn1560-7917-
dc.identifier.urihttp://hdl.handle.net/10722/356810-
dc.description.abstractWe isolated three genotypes of highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b from wild birds infected with H5N1 (n=12) and H5N8 (n=1) in Hong Kong SAR, 2021–2024. Viruses from two spoonbills from late 2022 were genetically related to a virus from a human in China. Four tested viruses exhibited variable virulence in mice but were susceptible to approved antivirals. No neutralising antibody was detected in 63 age-stratified human sera, suggesting potential risk should the virus adapt to humans.-
dc.languageeng-
dc.publisherEuropean Centre for Disease Prevention and Control-
dc.relation.ispartofEurosurveillance: Europe's journal on infectious disease surveillance, epidemiology, prevention and control-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleDetection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024-
dc.typeArticle-
dc.identifier.doi10.2807/1560-7917.ES.2025.30.1.2400839-
dc.identifier.pmid39790075-
dc.identifier.scopuseid_2-s2.0-85214929387-
dc.identifier.volume30-
dc.identifier.issue1-
dc.identifier.eissn1025-496X-
dc.identifier.isiWOS:001398303700001-
dc.identifier.issnl1025-496X-

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