Patients’ perception regarding clinical trial with lipo-filling for breast cancer management a pilot questionnaire analysis (Poster presentation)

Abstract

<p>Background: Breast cancer treatment has evolved significantly, with lipo-filling emerging as a promising option. However, patient perceptions and willingness to participate in clinical trials involving novel treatments remain underexplored.</p><p>Methods: A cross-sectional survey was conducted involving 200 breast cancer patients from August to December 2023. The questionnaire covered demographic information, clinical history, and detailed queries on their willingness to participate in clinical trials, with a focus on randomized trials and lipo-filling procedures. Statistical analysis was performed to identify correlations between demographics, clinical backgrounds, and their willingness to participate in trials.</p><p>Result: The average age of participants was 52.6 ± 12.9, predominantly with secondary education (55.5%) and a modest income ( < 1250 USG/month). A notable proportion of respondents were under breast cancer surveillance (31.5%), and had undergone lumpectomy (19.5%) and mastectomy (19.0%). The participants’ willingness to participate in a clinical trial with lipofilling surgery was hypothetically asked. 57.5% (114/200) of participants were willing to participate in the trial. However, when it asked about their willingness to participate in a randomized control trial setting, only 43.0% (75/200) participants expressed their desire to participate (p< 0.05). Further analysis was performed to stratify the different levels of willingness among the participants. We found that education levels (below secondary school level vs above), and salary (below 15k USG annual salary vs above) were associated with an increased willingness to participate in lipofilling surgery in a clinical trial setting (P < 0.05). Personal history of cancer and personal history of surgery showed no significant correlation with the willingness to participate in lipofilling surgery.</p><p>Conclusions: This study reveals a encouraging level of interest among breast patients in participating in clinical trials involving lipo-filling. The educational level and income play a significant role in this willingness and help provide further insight to help improve the trial planning and execution.</p>