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Book Chapter: Detection of Cancer-Derived Exosomes Using a Sensitive Colorimetric Aptasensor

TitleDetection of Cancer-Derived Exosomes Using a Sensitive Colorimetric Aptasensor
Authors
KeywordsAptamer
Aptasensor
Biomarker
Biosensor
Cancer detection
Exosomes
Issue Date2022
Citation
Methods in Molecular Biology, 2022, v. 2504, p. 21-30 How to Cite?
AbstractExosomes are a type of extracellular vesicles that contain constituents including proteins, DNAs, and RNAs of the cells that secrete them. Cancerous exosomes are potential biomarkers for cancer diagnosis. Biosensors are useful analytical tools for quantification of biomarkers and targeted molecules. An aptasensor uses the aptamer as the biorecognition element to bind to the target and is one main type of biosensors that is promising for exosomes analysis and clinical cancer detection. The assay described in this chapter allows for reliable, sensitive, and specific detection of cancer-derived exosomes using a colorimetric aptasensor that is promising for point-of-care testing.
Persistent Identifierhttp://hdl.handle.net/10722/349715
ISSN
2023 SCImago Journal Rankings: 0.399

 

DC FieldValueLanguage
dc.contributor.authorXu, Lizhou-
dc.contributor.authorAl-Jamal, Khuloud T.-
dc.date.accessioned2024-10-17T07:00:20Z-
dc.date.available2024-10-17T07:00:20Z-
dc.date.issued2022-
dc.identifier.citationMethods in Molecular Biology, 2022, v. 2504, p. 21-30-
dc.identifier.issn1064-3745-
dc.identifier.urihttp://hdl.handle.net/10722/349715-
dc.description.abstractExosomes are a type of extracellular vesicles that contain constituents including proteins, DNAs, and RNAs of the cells that secrete them. Cancerous exosomes are potential biomarkers for cancer diagnosis. Biosensors are useful analytical tools for quantification of biomarkers and targeted molecules. An aptasensor uses the aptamer as the biorecognition element to bind to the target and is one main type of biosensors that is promising for exosomes analysis and clinical cancer detection. The assay described in this chapter allows for reliable, sensitive, and specific detection of cancer-derived exosomes using a colorimetric aptasensor that is promising for point-of-care testing.-
dc.languageeng-
dc.relation.ispartofMethods in Molecular Biology-
dc.subjectAptamer-
dc.subjectAptasensor-
dc.subjectBiomarker-
dc.subjectBiosensor-
dc.subjectCancer detection-
dc.subjectExosomes-
dc.titleDetection of Cancer-Derived Exosomes Using a Sensitive Colorimetric Aptasensor-
dc.typeBook_Chapter-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/978-1-0716-2341-1_2-
dc.identifier.pmid35467276-
dc.identifier.scopuseid_2-s2.0-85128801968-
dc.identifier.volume2504-
dc.identifier.spage21-
dc.identifier.epage30-
dc.identifier.eissn1940-6029-

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